diff --git a/course_discovery/apps/api/tests/test_mixins.py b/course_discovery/apps/api/tests/test_mixins.py
index ec65daf897..50f71021ba 100644
--- a/course_discovery/apps/api/tests/test_mixins.py
+++ b/course_discovery/apps/api/tests/test_mixins.py
@@ -1,3 +1,5 @@
+import pytest
+
 from django.test.utils import override_settings
 from django.urls import path, reverse
 from mock import patch
@@ -68,6 +70,7 @@ def test_throttle_authenticated_user(self):
         assert response.data == "Hello, World"
         self.client.logout()
 
+    @pytest.mark.skip(reason="https://github.com/openedx/course-discovery/issues/4431")
     def test_throttle_limit__authentication_classes(self):
         """
         Verify that endpoint is throttled against unauthenticated users when requests are greater than limit.
diff --git a/course_discovery/apps/api/v1/tests/test_views/test_course_runs.py b/course_discovery/apps/api/v1/tests/test_views/test_course_runs.py
index 986cc19855..f9a07de3a3 100644
--- a/course_discovery/apps/api/v1/tests/test_views/test_course_runs.py
+++ b/course_discovery/apps/api/v1/tests/test_views/test_course_runs.py
@@ -1239,7 +1239,11 @@ def test_list_include_restricted(self, include_restriction_param):
         else:
             assert restricted_run.key not in retrieved_keys
 
-    @ddt.data([True, 4], [False, 3])
+    @ddt.data(
+        [True, 4],
+        # Skipping this because it's flaky: https://github.com/openedx/course-discovery/issues/4431
+        # [False, 3]
+    )
     @ddt.unpack
     def test_list_query_include_restricted(self, include_restriction_param, expected_result_count):
         CourseRunFactory.create_batch(3, title='Some cool title', course__partner=self.partner)
diff --git a/course_discovery/apps/api/v1/tests/test_views/test_courses.py b/course_discovery/apps/api/v1/tests/test_views/test_courses.py
index 4349d7fea9..885a3d841d 100644
--- a/course_discovery/apps/api/v1/tests/test_views/test_courses.py
+++ b/course_discovery/apps/api/v1/tests/test_views/test_courses.py
@@ -352,6 +352,7 @@ def test_list(self):
             self.serialize_course(Course.objects.all(), many=True)
         )
 
+    @pytest.mark.skip(reason="https://github.com/openedx/course-discovery/issues/4431")
     @responses.activate
     def test_list_query(self):
         """ Verify the endpoint returns a filtered list of courses """
@@ -366,6 +367,7 @@ def test_list_query(self):
             response = self.client.get(url)
         self.assertListEqual(response.data['results'], self.serialize_course(courses, many=True))
 
+    @pytest.mark.skip(reason="https://github.com/openedx/course-discovery/issues/4431")
     def test_list_key_filter(self):
         """ Verify the endpoint returns a list of courses filtered by the specified keys. """
         courses = CourseFactory.create_batch(3, partner=self.partner)