diff --git a/plugins/node/opentelemetry-instrumentation-redis-4/src/instrumentation.ts b/plugins/node/opentelemetry-instrumentation-redis-4/src/instrumentation.ts
index aa30a98822..3ac531847f 100644
--- a/plugins/node/opentelemetry-instrumentation-redis-4/src/instrumentation.ts
+++ b/plugins/node/opentelemetry-instrumentation-redis-4/src/instrumentation.ts
@@ -286,41 +286,61 @@ export class RedisInstrumentation extends InstrumentationBase<any> {
           return execRes;
         }
 
-        execRes.then((redisRes: unknown[]) => {
-          const openSpans = this[OTEL_OPEN_SPANS];
-          if (!openSpans) {
-            return plugin._diag.error(
-              'cannot find open spans to end for redis multi command'
-            );
-          }
-          if (redisRes.length !== openSpans.length) {
-            return plugin._diag.error(
-              'number of multi command spans does not match response from redis'
-            );
-          }
-          for (let i = 0; i < openSpans.length; i++) {
-            const { span, commandName, commandArgs } = openSpans[i];
-            const currCommandRes = redisRes[i];
-            if (currCommandRes instanceof Error) {
-              plugin._endSpanWithResponse(
-                span,
-                commandName,
-                commandArgs,
-                null,
-                currCommandRes
+        return execRes
+          .then((redisRes: unknown[]) => {
+            const openSpans = this[OTEL_OPEN_SPANS];
+            if (!openSpans) {
+              return plugin._diag.error(
+                'cannot find open spans to end for redis multi command'
+              );
+            }
+            if (redisRes.length !== openSpans.length) {
+              return plugin._diag.error(
+                'number of multi command spans does not match response from redis'
               );
-            } else {
+            }
+            for (let i = 0; i < openSpans.length; i++) {
+              const { span, commandName, commandArgs } = openSpans[i];
+              const currCommandRes = redisRes[i];
+              if (currCommandRes instanceof Error) {
+                plugin._endSpanWithResponse(
+                  span,
+                  commandName,
+                  commandArgs,
+                  null,
+                  currCommandRes
+                );
+              } else {
+                plugin._endSpanWithResponse(
+                  span,
+                  commandName,
+                  commandArgs,
+                  currCommandRes,
+                  undefined
+                );
+              }
+            }
+            return redisRes;
+          })
+          .catch((err: Error) => {
+            const openSpans = this[OTEL_OPEN_SPANS];
+            if (!openSpans) {
+              return plugin._diag.error(
+                'cannot find open spans to end for redis multi command'
+              );
+            }
+            for (let i = 0; i < openSpans.length; i++) {
+              const { span, commandName, commandArgs } = openSpans[i];
               plugin._endSpanWithResponse(
                 span,
                 commandName,
                 commandArgs,
-                currCommandRes,
-                undefined
+                null,
+                err
               );
             }
-          }
-        });
-        return execRes;
+            return Promise.reject(err);
+          });
       };
     };
   }
diff --git a/plugins/node/opentelemetry-instrumentation-redis-4/test/redis.test.ts b/plugins/node/opentelemetry-instrumentation-redis-4/test/redis.test.ts
index ac5abf5bce..74fa7b699c 100644
--- a/plugins/node/opentelemetry-instrumentation-redis-4/test/redis.test.ts
+++ b/plugins/node/opentelemetry-instrumentation-redis-4/test/redis.test.ts
@@ -32,7 +32,7 @@ const instrumentation = registerInstrumentationTesting(
   new RedisInstrumentation()
 );
 
-import { createClient } from 'redis';
+import { createClient, WatchError } from 'redis';
 import {
   Span,
   SpanKind,
@@ -398,6 +398,26 @@ describe('redis@^4.0.0', () => {
       );
     });
 
+    it('multi command that rejects', async () => {
+      const watchedKey = 'watched-key';
+      await client.watch(watchedKey);
+      await client.set(watchedKey, 'a different value');
+      try {
+        await client.multi().get(watchedKey).exec();
+        assert.fail('expected WatchError to be thrown and caught in try/catch');
+      } catch (error) {
+        assert.ok(error instanceof WatchError);
+      }
+
+      // All the multi spans' status are set to ERROR.
+      const [_watchSpan, _setSpan, multiGetSpan] = getTestSpans();
+      assert.strictEqual(multiGetSpan?.status.code, SpanStatusCode.ERROR);
+      assert.strictEqual(
+        multiGetSpan?.status.message,
+        'One (or more) of the watched keys has been changed'
+      );
+    });
+
     it('duration covers create until server response', async () => {
       await client.set('another-key', 'another-value');
       const multiClient = client.multi();