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rewrite site in jekyll/bootstrap by forking allan lab site
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_config.yml

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permalink: pretty
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# Setup
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title: Simpson Lab Blog
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tagline: 'SimpsonLab blog'
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description: 'A blog for the Simpson Lab at the Ontario Institute for Cancer Research'
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url: simpsonlab.github.io
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baseurl: /
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title: Simpson Lab Webpage
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tagline: 'SimpsonLab Webpage'
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description: 'Simpson Lab at the Ontario Institute for Cancer Research'
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baseurl: ""
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url: ""
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include:
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- .htaccess
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- _pages
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sass:
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sass_dir: _sass
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author:
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name: 'Jared Simpson'
@@ -22,10 +29,6 @@ paginate: 5
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version: 1.0
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markdown: kramdown
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pages_list:
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About: '/about'
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Archive: '/archive'
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authors:
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jared:
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display_name: Jared Simpson

_data/courselist.yml

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- title: "Algorithms for Genome Sequence Analysis"
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term: 2016 Fall
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type: course
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link:
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url: https://jts.github.io/csc2417/
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display: "CSC 2417"
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- title: "Informatics on High-throughput Sequencing Data"
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term: 2014-2017
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type: cbw
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link:
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url: https://bioinformatics.ca/workshops
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display: "CBW"
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- title: "Bioinformatics for Cancer Genomics"
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term: 2013-2017
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type: cbw
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link:
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url: https://bioinformatics.ca/workshops
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display: "CBW"
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_data/pub_links.tsv

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"Epidemic establishment and cryptic transmission of Zika virus in Brazil and the Americas" http://biorxiv.org/content/early/2017/02/02/105171
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"De novo genome and transcriptome assembly of the Canadian beaver (Castor canadensis)" http://www.g3journal.org/content/early/2017/01/13/g3.116.038208.1
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"Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples" http://biorxiv.org/content/early/2017/01/09/098913
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"A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns" http://www.nature.com/nature/journal/v538/n7625/full/nature19823.html
5+
"Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly" http://biorxiv.org/content/early/2016/08/30/072116
6+
"Using reference-free compressed data structures to analyse sequencing reads from thousands of human genomes" http://genome.cshlp.org/content/27/2/300.abstract
7+
"A global reference for human genetic variation" http://www.nature.com/nature/journal/v526/n7571/full/nature15393.html
8+
"trio-sga: facilitating de novo assembly of highly heterozygous genomes with parent-child trios" http://biorxiv.org/content/early/2016/05/03/051516
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"Detecting DNA Methylation using the Oxford Nanopore Technologies MinION sequencer" http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.4184.html
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"Nanocall: an open source basecaller for Oxford Nanopore sequencing data" https://academic.oup.com/bioinformatics/article/33/1/49/2525680/Nanocall-an-open-source-basecaller-for-Oxford
11+
"Real-time, portable genome sequencing for Ebola surveillance" http://www.nature.com/nature/journal/v530/n7589/full/nature16996.html
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"A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing" http://www.nature.com/articles/ncomms10001
13+
"MinION Analysis and Reference Consortium: Phase 1 data release and analysis" https://f1000research.com/articles/4-1075/v1
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"The khmer software package: enabling efficient nucleotide sequence analysis" https://f1000research.com/articles/4-900/v1
15+
"A complete bacterial genome assembled de novo using only nanopore sequencing data" http://www.nature.com/nmeth/journal/v12/n8/full/nmeth.3444.html
16+
"The genomic and phenotypic diversity of Schizosaccharomyces pombe" http://www.nature.com/ng/journal/v47/n3/full/ng.3215.html
17+
"The theory and practice of genome sequence assembly" http://www.annualreviews.org/doi/abs/10.1146/annurev-genom-090314-050032?journalCode=genom
18+
"A high-definition view of functional genetic variation from natural yeast genomes" https://academic.oup.com/mbe/article/31/4/872/1103434/A-High-Definition-View-of-Functional-Genetic
19+
"Exploring genome characteristics and sequence quality without a reference" https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btu023
20+
"Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species" https://gigascience.biomedcentral.com/articles/10.1186/2047-217X-2-10
21+
"Insights into hominid evolution from the gorilla genome sequence" http://www.nature.com/nature/journal/v483/n7388/full/nature10842.html
22+
"Efficient de novo assembly of large genomes using compressed data structures" http://genome.cshlp.org/content/early/2011/12/07/gr.126953.111
23+
"Assemblathon 1: a competitive assessment of de novo short read assembly methods" http://genome.cshlp.org/content/early/2011/09/16/gr.126599.111.abstract
24+
"Trait variation in yeast is defined by population history" http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002111
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"Copy number variant detection in inbred strains from short read sequence data" https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btp693
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"Revealing the genetic structure of a trait by sequencing a population under selection" http://genome.cshlp.org/content/21/7/1131.full
27+
"Efficient construction of an assembly string graph using the FM-index" https://academic.oup.com/bioinformatics/article/26/12/i367/286190/Efficient-construction-of-an-assembly-string-graph
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"Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels" https://genomebiology.biomedcentral.com/articles/10.1186/gb-2009-10-10-r112
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"Complex landscapes of somatic rearrangement in human breast cancer genomes" http://www.nature.com/nature/journal/v462/n7276/full/nature08645.html
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"ABySS: a parallel assembler for short read sequence data" http://genome.cshlp.org/content/19/6/1117

_data/publist.yml

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- title: "Detecting DNA Methylation using the Oxford Nanopore Technologies MinION sequencer"
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authors: Jared T Simpson, Rachael Workman, Philip C Zuzarte, Matei David, Lewis Jonathan Dursi, Winston Timp
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year: 2017
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preprint: 0
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link:
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url: http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.4184.html
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display: "Nature Methods"
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- title: "Epidemic establishment and cryptic transmission of Zika virus in Brazil and the Americas"
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authors: Nuno R Faria, Josh Quick, Ingra Morales, Julien Theze, Jacqueline G de Jesus, Marta Giovanetti, Moritz UG Kraemer, Sarah C Hill et al.
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year: 2017
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preprint: 1
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link:
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url: http://biorxiv.org/content/early/2017/02/02/105171
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display: "bioRxiv"
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- title: "De novo genome and transcriptome assembly of the Canadian beaver (Castor canadensis)"
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authors: Si Lok, Tara A Paton, Zhuozhi Wang, Gaganjot Kaur, Susan Walker, Ryan KC Yuen, Wilson WL Sung, Joseph Whitney et al.
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year: 2017
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preprint: 0
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link:
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url: http://www.g3journal.org/content/early/2017/01/13/g3.116.038208.1
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display: "G3: Genes, Genomes, Genetics"
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- title: "Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples"
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authors: Joshua Quick, Nathan D Grubaugh, Steven T Pullan, Ingra M Claro, Andrew D Smith, Karthik Gangavarapu, Glenn Oliveira, Refugio Robles-Sikisaka et al.
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year: 2017
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preprint: 1
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link:
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url: http://biorxiv.org/content/early/2017/01/09/098913
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display: "bioRxiv"
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- title: "A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns"
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authors: Faiyaz Notta, Michelle Chan-Seng-Yue, Mathieu Lemire, Yilong Li, Gavin W Wilson, Ashton A Connor, Robert E Denroche, Sheng-Ben Liang et al.
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year: 2016
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preprint: 0
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link:
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url: http://www.nature.com/nature/journal/v538/n7625/full/nature19823.html
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display: "Nature"
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- title: "Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly"
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authors: Valerie A Schneider, Tina Graves Lindsay, Kerstin Howe, Nathan Bouk, Hsiu-Chuan Chen, Paul A Kitts, Terence D Murphy, Kim D Pruitt et al.
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year: 2016
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preprint: 1
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link:
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url: http://biorxiv.org/content/early/2016/08/30/072116
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display: "bioRxiv"
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- title: "Using reference-free compressed data structures to analyse sequencing reads from thousands of human genomes"
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authors: Dirk-Dominic Dolle, Zhicheng Liu, Matthew L Cotten, Jared T Simpson, Zamin Iqbal, Richard Durbin, Shane A McCarthy, Thomas M Keane
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year: 2016
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preprint: 0
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link:
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url: http://genome.cshlp.org/content/27/2/300.abstract
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display: "Genome Research"
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- title: "A global reference for human genetic variation"
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authors: 1000 Genomes Project Consortium et al.
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year: 2015
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preprint: 0
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link:
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url: http://www.nature.com/nature/journal/v526/n7571/full/nature15393.html
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display: "Nature"
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- title: "trio-sga: facilitating de novo assembly of highly heterozygous genomes with parent-child trios"
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authors: Milan Malinsky, Jared T Simpson, Richard Durbin
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year: 2016
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preprint: 1
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link:
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url: http://biorxiv.org/content/early/2016/05/03/051516
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display: "bioRxiv"
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- title: "Nanocall: an open source basecaller for Oxford Nanopore sequencing data"
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authors: Matei David, Lewis Jonathan Dursi, Delia Yao, Paul C Boutros, Jared T Simpson
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year: 2016
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preprint: 0
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link:
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url: https://academic.oup.com/bioinformatics/article/33/1/49/2525680/Nanocall-an-open-source-basecaller-for-Oxford
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display: "Bioinformatics"
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- title: "Real-time, portable genome sequencing for Ebola surveillance"
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authors: Joshua Quick, Nicholas J Loman, Sophie Duraffour, Jared T Simpson, Ettore Severi, Lauren Cowley, Joseph Akoi Bore, Raymond Koundouno et al.
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year: 2016
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preprint: 0
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link:
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url: http://www.nature.com/nature/journal/v530/n7589/full/nature16996.html
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display: "Nature"
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- title: "A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing"
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authors: Tyler S Alioto, Ivo Buchhalter, Sophia Derdak, Barbara Hutter, Matthew D Eldridge, Eivind Hovig, Lawrence E Heisler, Timothy A Beck et al.
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year: 2015
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preprint: 0
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link:
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url: http://www.nature.com/articles/ncomms10001
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display: "Nature communications"
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- title: "MinION Analysis and Reference Consortium: Phase 1 data release and analysis"
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authors: Camilla LC Ip, Matthew Loose, John R Tyson, Mariateresa de Cesare, Bonnie L Brown, Miten Jain, Richard M Leggett, David A Eccles et al.
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year: 2015
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preprint: 0
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link:
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url: https://f1000research.com/articles/4-1075/v1
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display: "F1000Research"
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- title: "The khmer software package: enabling efficient nucleotide sequence analysis"
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authors: Michael R Crusoe, Hussien F Alameldin, Sherine Awad, Elmar Boucher, Adam Caldwell, Reed Cartwright, Amanda Charbonneau, Bede Constantinides et al.
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year: 2015
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preprint: 0
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link:
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url: https://f1000research.com/articles/4-900/v1
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display: "F1000Research"
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- title: "A complete bacterial genome assembled de novo using only nanopore sequencing data"
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authors: Nicholas J Loman, Joshua Quick, Jared T Simpson
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year: 2015
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preprint: 0
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link:
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url: http://www.nature.com/nmeth/journal/v12/n8/full/nmeth.3444.html
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display: "Nature methods"
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- title: "The genomic and phenotypic diversity of Schizosaccharomyces pombe"
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authors: Daniel C Jeffares, Charalampos Rallis, Adrien Rieux, Doug Speed, Martin P{ř}evorovsk{ỳ}, Tobias Mourier, Francesc X Marsellach, Zamin Iqbal et al.
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year: 2015
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preprint: 0
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link:
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url: http://www.nature.com/ng/journal/v47/n3/full/ng.3215.html
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display: "Nature genetics"
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- title: "The theory and practice of genome sequence assembly"
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authors: Jared T Simpson, Mihai Pop
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year: 2015
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preprint: 0
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link:
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url: http://www.annualreviews.org/doi/abs/10.1146/annurev-genom-090314-050032?journalCode=genom
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display: "Annual review of genomics and human genetics"
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- title: "A high-definition view of functional genetic variation from natural yeast genomes"
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authors: Anders Bergström, Jared T Simpson, Francisco Salinas, Benjamin Barré, Leopold Parts, Amin Zia, Alex N Nguyen Ba, Alan M Moses et al.
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year: 2014
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preprint: 0
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link:
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url: https://academic.oup.com/mbe/article/31/4/872/1103434/A-High-Definition-View-of-Functional-Genetic
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display: "Molecular biology and evolution"
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- title: "Exploring genome characteristics and sequence quality without a reference"
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authors: Jared T Simpson
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year: 2014
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preprint: 0
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link:
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url: https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btu023
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display: "Bioinformatics"
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- title: "Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species"
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authors: Keith R Bradnam, Joseph N Fass, Anton Alexandrov, Paul Baranay, Michael Bechner, Inan{ç} Birol, Sébastien Boisvert, Jarrod A Chapman et al.
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year: 2013
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preprint: 0
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link:
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url: https://gigascience.biomedcentral.com/articles/10.1186/2047-217X-2-10
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display: "GigaScience"
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- title: "Insights into hominid evolution from the gorilla genome sequence"
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authors: Aylwyn Scally, Julien Y Dutheil, LaDeana W Hillier, Gregory E Jordan, Ian Goodhead, Javier Herrero, Asger Hobolth, Tuuli Lappalainen et al.
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year: 2012
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preprint: 0
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link:
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url: http://www.nature.com/nature/journal/v483/n7388/full/nature10842.html
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display: "Nature"
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- title: "Efficient de novo assembly of large genomes using compressed data structures"
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authors: Jared T Simpson, Richard Durbin
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year: 2012
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preprint: 0
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link:
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url: http://genome.cshlp.org/content/early/2011/12/07/gr.126953.111
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display: "Genome research"
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- title: "Assemblathon 1: a competitive assessment of de novo short read assembly methods"
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authors: Dent Earl, Keith Bradnam, John St John, Aaron Darling, Dawei Lin, Joseph Fass, Hung On Ken Yu, Vince Buffalo et al.
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year: 2011
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preprint: 0
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link:
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url: http://genome.cshlp.org/content/early/2011/09/16/gr.126599.111.abstract
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display: "Genome research"
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- title: "Trait variation in yeast is defined by population history"
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authors: Jonas Warringer, Enikö Zörgö, Francisco A Cubillos, Amin Zia, Arne Gjuvsland, Jared T Simpson, Annabelle Forsmark, Richard Durbin et al.
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year: 2011
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preprint: 0
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link:
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url: http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002111
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display: "PLoS Genet"
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- title: "Copy number variant detection in inbred strains from short read sequence data"
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authors: Jared T Simpson, Rebecca E McIntyre, David J Adams, Richard Durbin
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year: 2010
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preprint: 0
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link:
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url: https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btp693
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display: "Bioinformatics"
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- title: "Revealing the genetic structure of a trait by sequencing a population under selection"
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authors: Leopold Parts, Francisco A Cubillos, Jonas Warringer, Kanika Jain, Francisco Salinas, Suzannah J Bumpstead, Mikael Molin, Amin Zia et al.
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year: 2011
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preprint: 0
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link:
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url: http://genome.cshlp.org/content/21/7/1131.full
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display: "Genome research"
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- title: "Efficient construction of an assembly string graph using the FM-index"
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authors: Jared T Simpson, Richard Durbin
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year: 2010
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preprint: 0
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link:
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url: https://academic.oup.com/bioinformatics/article/26/12/i367/286190/Efficient-construction-of-an-assembly-string-graph
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display: "Bioinformatics"
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- title: "Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels"
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authors: Ian Sudbery, Jim Stalker, Jared T Simpson, Thomas Keane, Alistair G Rust, Matthew E Hurles, Klaudia Walter, Dee Lynch et al.
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year: 2009
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preprint: 0
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link:
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url: https://genomebiology.biomedcentral.com/articles/10.1186/gb-2009-10-10-r112
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display: "Genome biology"
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- title: "Complex landscapes of somatic rearrangement in human breast cancer genomes"
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authors: Philip J Stephens, David J McBride, Meng-Lay Lin, Ignacio Varela, Erin D Pleasance, Jared T Simpson, Lucy A Stebbings, Catherine Leroy et al.
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year: 2009
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preprint: 0
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link:
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url: http://www.nature.com/nature/journal/v462/n7276/full/nature08645.html
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display: "Nature"
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- title: "ABySS: a parallel assembler for short read sequence data"
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authors: Jared T Simpson, Kim Wong, Shaun D Jackman, Jacqueline E Schein, Steven JM Jones, Inan{ç} Birol
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year: 2009
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preprint: 0
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link:
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url: http://genome.cshlp.org/content/19/6/1117
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display: "Genome research"
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_data/team_members.yml

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- name: Jared Simpson
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photo: jared.png
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info: Principal Investigator, started 2013
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github: https://github.com/jts
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twitter: https://twitter.com/jaredtsimpson
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number_educ: 2
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education1: PhD, University of Cambridge
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education2: BSc, University of British Columbia
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- name: Matei David
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photo: matei.jpg
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info: Research Software Developer, started 2013
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github: github.com/mateidavid
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twitter: https://twitter.com/mateidvd
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number_educ: 2
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education1: PhD, University of Toronto
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education2: BSc, University of Toronto
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- name: Heather Gibling
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photo: heather.jpg
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info: Graduate Student, started 2016
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github: github.com/hgibling
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twitter: https://twitter.com/hgibling
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number_educ: 2
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education1: MBinf, University of Guelph
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education2: BSc, University of Calgary
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- name: Paul Tang
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photo: paul.jpg
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info: Computational Biologist, started 2016
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github: paulswtang
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twitter: 0
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number_educ: 1
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education1: BSc, McGill University

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