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Copy file name to clipboardexpand all lines: docs/damid.rst
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DamID principle
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DamID is a method that identifies genomic binding sites of a protein of interest (POI). In contrast to ChIP-seq, no antibodies again the POI are required.
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DamID is a method that identifies genomic binding sites of a protein of interest (POI). In contrast to ChIP-seq, no antibodies against the POI are required.
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The method is based on fusing the POI to a DNA adenine methyltransferase (Dam) from *E. coli*. Dam methylates adenine bases in GATC motifs, which are not present in the eukaryotic genome.
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