new variant caller: MuSE

[famosab]

Description of feature

MuSE is a somatic point mutation caller which works with whole-genome sequencing (WGS) and whole-exome sequencing (WES) data.

This tool is unique in accounting for tumor heterogeneity using a sample-specific error model that improves sensitivity and specificity in mutation calling from sequencing data.

MuSE was used in the TCGA PanCanAtlas project2 and the ICGC Pan-Cancer Analysis of Whole Genomes (PCAWG) initiative. I would like to use it with sarek to do some follow-up analysis comparison of TCGA processed data and raw data.

The modules are already created and ready in nf-core/modules. I would try and do the integration myself.