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FigS6_SyntheticMorphologies

Fig S6

This data was generated from multiple resources:

  1. GRNs: Generated using Cx3D's GenerateGRNs
  2. Generation of morphologies: run_simulations_simple.py . The script assumes sciview and Cx3D to be available locally (instructions), since morphologies are actually generated in Cx3D using GRNBranchingSWC
  3. Extraction of metrics: ExtractMetrics.groovy
  4. Statistical analysis: analysis.py
  5. Density maps: Generated using DensityPlot2DTest. Montage of projections generated using RenderMaps
  6. Exemplars: Generated using render_exemplars

NB:

  • Some of the code above uses hardwired paths. Please change them accordingly
  • GRNs used in the manuscript are made available in grn/. These can be inspected using grneat
  • Retrieved metrics are included in csv/
  • The 5,000 morphologies account for more than 300MB of data and were not included in this repository, but exemplars are included in swc/

Below some of the outputs of analysis.py:

Metrics matrix for all GRNs:

Distributions of metrics across all GRNs: