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drug2.txt
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drug2.txt
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Drug Name Drug Synonyms Targets PubCHEM ID
17-AAG 17-AAG HSP90 6505803
681640 681640 WEE1,CHK1 10384072
A-443654 KIN001-139 AKT1/2/3 10172943
A-769662 AMPKagonist 11360391
A-770041 A770041,KIN001-111 SRCfamily 9549184
ABT-263 BCL2,BCL-XL,BCL-W 24978538
ABT-888 ABT-888 PARP1/2 11960529
AG-014699 PF-01367338 PARP1,PARP2 9931953
AICAR N1-(b-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide AMPKagonist 65110
AKTinhibitorVIII AKT1/2 16218954
AMG-706 AMG-706 VEGFR,RET,c-KIT,PDGFR 11667893
AP-24534 AP24534(KIN001-192) ABL 24826799
AS601245 AS601245 JNK 11422035
ATRA Tretinoin RetinoicacidandretinoidXreceptoragonist 444795
AUY922 VER-52296,NVP-AUY922 HSP90 10096043
Axitinib AG-013736 PDGFR,KIT,VEGFR 6450551
AZ628 BRAF 11676786
AZD-0530 Saracatinib,KIN001-045 SRC,ABL1 10302451
AZD-2281 KU-0059436,Olaparib PARP1/2 23725625
AZD6244 MEK1/2 10127622
AZD6482 AZD6482(KIN001-193) PI3Kb(P3C2B) 44137675
AZD7762 AZD7762 CHK1/2
AZD8055 AZD8055 mTORC1/2
BAY61-3606 SYK 16760671
Bexarotene LG-100069,LGD-1069 RetinioicacidXfamilyagonist 82146
BI-2536 KIN001-124 PLK1/2/3 11364421
BI-D1870 BI-D1870 RSK1/2/3/5,PLK1,AURKB 25023738
BIBW2992 Tovok,Afatinib EGFR,ERBB2 10184653
Bicalutamide ICI-176334 Androgenreceptor(ANDR) 2375
BIRB0796 p38,JNK2 156422
Bleomycin DNAdamage 5460769
BMS-509744 KIN001-127 ITK 20635522
BMS-536924 KIN001-126 IGF1R 10390396
BMS-708163 Avagacestat gamma-secretase 46883536
BMS-754807 IGF1R 24785538
Bortezomib LDP-341,PS-341 Proteasome 387447
Bosutinib SKI-606 SRC,ABL,TEC 5328940
Bryostatin1 Bryostatin1 PRKC 5280757
BX-795 BX795 TBK1,PDK1,IKK,AURKB/C 10077147
Camptothecin 7-Ethyl-10-Hydroxy-Camptothecin,SN-38 TOP1 104842
CCT007093 PPM1D
CCT018159 HSP90
CEP-701 CEP-701 FLT3,JAK2,NTRK1,RET 126565
CGP-082996 CINK4,KIN001-021 CDK4 24825971
CGP-60474 KIN001-019 CDK1/2/5/7/9 644215
CHIR-99021 CT99021 GSK3B 9956119
CI-1040 PD-18435,PD-184352 MEK1/2 6918454
Cisplatin cis-Diammineplatinum(II)dichloride DNAcrosslinker 84691
CMK KIN001-128 RSK NOMATCH
Cyclopamine 11-deoxojervine SMO 442972
Cytarabine Ara-Cytidine,ArabinosylCytosine,U-19920 DNAsynthesis 6253
Dasatinib KIN001-005 ABL,SRC,KIT,PDGFR 3062316
DMOG Dimethyloxalylglcine Prolyl-4-Hydroxylase 560326
Docetaxel RP-56976 Microtubules 148124
Doxorubicin Doxil,Rubex DNAintercalating 31703
EHT1864 RacGTPases
Elesclomol HSP70
Embelin XIAP 3218
EpothiloneB GNF-PF-193 Microtubules 448013
Erlotinib EGFR 176870
Etoposide TOP2 36462
FH535 FH535 unknown 3463933
FTI-277 Farnesyltransferase(FNTA) 3005532
GDC-0449 SMO 24776445
GDC0941 PI3K(class1) 17755052
Gefitinib ZD-1839 EGFR 123631
Gemcitabine Gemzar,LY-188011 DNAreplication 60750
GNF-2 KIN001-013(GNF-2/3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide) BCR-ABL 5311510
GSK-650394 SGK3 25022668
GSK269962A KIN001-155 ROCK 16095342
GW441756 NTRK1
GW843682X KIN001-134 PLK1 15983966
Imatinib Gleevec,STI-571 ABL,KIT,PDGFR 5291
IPA-3 IPA-3 PAK 521106
JNJ-26854165 MDM2 11609586
JNKInhibitorVIII JNKInhibitorVIII JNK 11624601
JNK-9L KIN001-204 JNK NOMATCH
JW-7-52-1 MTOR 49836027
KIN001-135 KIN001-135 IKKE 11626927
KU-55933 ATM 5278396
Lapatinib EGFR,ERBB2 208908
Lenalidomide TNFalpha 216326
LFM-A13 DDE-28 BTK 9549280
Metformin 1,1-Dimethylbiguanidehydrochloride AMPKagonist 4091
Methotrexate Dihydrofolatereductase(DHFR) 126941
MG-132 zLLL Proteasome 462382
Midostaurin PKC412 KIT 24202429
MitomycinC Mytozytrex,NSC-26980 DNAcrosslinker 5746
MK-2206 AKT1/2
MS-275 MS275 HDAC 4261
Nilotinib ABL 644241
NSC-87877 SHP1/2(PTN6/11) 5459322
NU-7441 NU-7432,KU-57788 DNAPK 11327430
Nutlin-3a Nutlin-3a(-)enantiomer MDM2 11433190
NVP-BEZ235 BEZ235 PI3K(Class1)andmTORC1/2
NVP-TAE684 KIN001-017 ALK 16038120
ObatoclaxMesylate BCL-2,BCL-XL,MCL-1 16727411
OSI-906 OSI-906 IGF1R 11640390
PAC-1 PAC-1 CASP3activator 6851947
Paclitaxel BMS-181339-01 Microtubules 36314
Parthenolide NFKB1 5420805
Pazopanib GW786034 VEGFR,PDGFRA,PDGFRB,KIT 10113978
PD-0325901 PD-0325901 MEK1/2 9826528
PD-0332991 PD-0332991 CDK4/6 5330286
PD-173074 PD-173074 FGFR1/3 1401
PF-02341066 Crizotinib,KIN001-023 MET,ALK 11496366
PF-4708671 p70S6KA
PF-562271 (KIN001-205) FAK 11713159
PHA-665752 MET 10461815
PLX4720 BRAF 24180719
Pyrimethamine Dihydrofolatereductase(DHFR) 4993
QS11 QS11 ARFGAP NoMatch
Rapamycin AY-22989,Sirolimus,WY-090217 MTOR 5284616
RDEA119 RDEA119 MEK1/2 44182295
RO-3306 CDK1 44450571
Roscovitine Seliciclib CDKs 160355
S-Trityl-L-cysteine NSC83265 KIF11 76044
Salubrinal 3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide GADD34-PP1Cphosphatase 5717801
SB216763 SB216763 GSK3A/B
SB590885 BRAF 11316960
Shikonin Shikonin unknown 5208
SL0101-1 RSK,AURKB,PIM3
Sorafenib BAY-43-9006,Nexavar PDGFRA,PDGFRB,KDR,KIT,FLT3 216239
Sunitinib Sutent PDGFRA,PDGFRB,KDR,KIT,FLT3 5329102
Temsirolimus CCI-779 MTOR 6918289
Thapsigargin ATPase,Ca++transporting,cardiacmuscle,slowtwitch2 446378
Tipifarnib Farnesyl-transferase(FNTA) 159324
TW37 BCL-2,BCL-XL 11455910
Vinblastine Vinblastinesulphate Microtubules 6710780
Vinorelbine Microtubules 60780
Vorinostat SAHA HDACinhibitorClassI,IIa,IIb,IV 5311
VX-680 MK-045,MK-0457,VX-68 AuroraA/B/C,FLT3,ABL1,JAK2, 5494449
VX-702 p38 10341154
WH-4-023 KIN001-112 SRCfamily,ABL 11844351
WO2009093972 AZD6482 PI3Kb
WZ-1-84 KIN001-123 BMX 49821040
XMD8-85 XMD8-85 ERK5(MK07) 46844147
Z-LLNle-CHO Z-L-Norleucine-CHO g-secretase 16760646
ZM-447439 ZM447439 AURKB 9914412