diff --git a/desc/argument.go b/desc/argument.go
index 5d92643..7f7b325 100644
--- a/desc/argument.go
+++ b/desc/argument.go
@@ -3,6 +3,8 @@ package desc
 import (
 	"fmt"
 	"reflect"
+
+	"github.com/jackc/pgx/v5/pgtype/zeronull"
 )
 
 // Argument represents a single argument for a database query
@@ -69,6 +71,7 @@ func extractArguments(td *Table, structValue reflect.Value, filter func(columnNa
 
 		fieldValue := field.Interface() // get the field value as an interface
 
+		// If filter passed, respect just the filter.
 		if filter != nil {
 			if !filter(c.Name) {
 				continue
@@ -83,7 +86,7 @@ func extractArguments(td *Table, structValue reflect.Value, filter func(columnNa
 			}
 		}
 
-		if c.Default != "" && c.Type == UUID && c.PrimaryKey && !c.Nullable {
+		if c.Default != "" && c.Type == UUID && !c.Nullable && c.PrimaryKey {
 			if isZero(fieldValue) {
 				continue // skip this field if it is a UUID primary key and required and the field value is zero
 			}
@@ -117,10 +120,10 @@ func extractArguments(td *Table, structValue reflect.Value, filter func(columnNa
 }
 
 // filterArguments takes a slice of arguments and a filter function and returns a slice of arguments.
-func filterArguments(args Arguments, filter func(arg Argument) bool) Arguments {
+func filterArguments(args Arguments, filter func(arg *Argument) bool) Arguments {
 	var filtered Arguments
 	for _, arg := range args {
-		if filter(arg) {
+		if filter(&arg) {
 			filtered = append(filtered, arg)
 		}
 	}
@@ -129,8 +132,19 @@ func filterArguments(args Arguments, filter func(arg Argument) bool) Arguments {
 
 // FilterArgumentsForInsert takes a slice of arguments and returns a slice of arguments for insert.
 func filterArgumentsForFullUpdate(args Arguments) Arguments {
-	return filterArguments(args, func(arg Argument) bool {
-		return !arg.Column.IsGenerated() && !arg.Column.Presenter // && !arg.Column.Unscannable
+	return filterArguments(args, func(arg *Argument) bool {
+		c := arg.Column
+
+		if (c.PrimaryKey || c.ReferenceColumnName != "") && c.Default != "" && c.Type == UUID && c.Nullable {
+			if isZero(arg.Value) { // fixes full update of a record which contains an optional reference UUID, we allow setting it to null, but
+				// we have to replace empty string with zeronull.UUID{}. Note that on insert we omit it from the query, as it will default to the default sql line default value.
+				arg.Value = zeronull.UUID{}
+			}
+
+			return true
+		}
+
+		return !c.IsGenerated() && !c.Presenter // && !arg.Column.Unscannable
 	})
 }
 
diff --git a/go.mod b/go.mod
index c32cb7a..deec20b 100644
--- a/go.mod
+++ b/go.mod
@@ -12,7 +12,7 @@ require (
 	github.com/jackc/pgpassfile v1.0.0 // indirect
 	github.com/jackc/pgservicefile v0.0.0-20221227161230-091c0ba34f0a // indirect
 	github.com/jackc/puddle/v2 v2.2.1 // indirect
-	golang.org/x/crypto v0.14.0 // indirect
+	golang.org/x/crypto v0.15.0 // indirect
 	golang.org/x/sync v0.5.0 // indirect
-	golang.org/x/text v0.13.0 // indirect
+	golang.org/x/text v0.14.0 // indirect
 )
diff --git a/go.sum b/go.sum
index 9451410..602ff22 100644
--- a/go.sum
+++ b/go.sum
@@ -18,14 +18,14 @@ github.com/stretchr/testify v1.3.0/go.mod h1:M5WIy9Dh21IEIfnGCwXGc5bZfKNJtfHm1UV
 github.com/stretchr/testify v1.7.0/go.mod h1:6Fq8oRcR53rry900zMqJjRRixrwX3KX962/h/Wwjteg=
 github.com/stretchr/testify v1.8.1 h1:w7B6lhMri9wdJUVmEZPGGhZzrYTPvgJArz7wNPgYKsk=
 github.com/stretchr/testify v1.8.1/go.mod h1:w2LPCIKwWwSfY2zedu0+kehJoqGctiVI29o6fzry7u4=
-golang.org/x/crypto v0.14.0 h1:wBqGXzWJW6m1XrIKlAH0Hs1JJ7+9KBwnIO8v66Q9cHc=
-golang.org/x/crypto v0.14.0/go.mod h1:MVFd36DqK4CsrnJYDkBA3VC4m2GkXAM0PvzMCn4JQf4=
+golang.org/x/crypto v0.15.0 h1:frVn1TEaCEaZcn3Tmd7Y2b5KKPaZ+I32Q2OA3kYp5TA=
+golang.org/x/crypto v0.15.0/go.mod h1:4ChreQoLWfG3xLDer1WdlH5NdlQ3+mwnQq1YTKY+72g=
 golang.org/x/mod v0.14.0 h1:dGoOF9QVLYng8IHTm7BAyWqCqSheQ5pYWGhzW00YJr0=
 golang.org/x/mod v0.14.0/go.mod h1:hTbmBsO62+eylJbnUtE2MGJUyE7QWk4xUqPFrRgJ+7c=
 golang.org/x/sync v0.5.0 h1:60k92dhOjHxJkrqnwsfl8KuaHbn/5dl0lUPUklKo3qE=
 golang.org/x/sync v0.5.0/go.mod h1:Czt+wKu1gCyEFDUtn0jG5QVvpJ6rzVqr5aXyt9drQfk=
-golang.org/x/text v0.13.0 h1:ablQoSUd0tRdKxZewP80B+BaqeKJuVhuRxj/dkrun3k=
-golang.org/x/text v0.13.0/go.mod h1:TvPlkZtksWOMsz7fbANvkp4WM8x/WCo/om8BMLbz+aE=
+golang.org/x/text v0.14.0 h1:ScX5w1eTa3QqT8oi6+ziP7dTV1S2+ALU0bI+0zXKWiQ=
+golang.org/x/text v0.14.0/go.mod h1:18ZOQIKpY8NJVqYksKHtTdi31H5itFRjB5/qKTNYzSU=
 gopkg.in/check.v1 v0.0.0-20161208181325-20d25e280405/go.mod h1:Co6ibVJAznAaIkqp8huTwlJQCZ016jof/cbN4VW5Yz0=
 gopkg.in/yaml.v3 v3.0.0-20200313102051-9f266ea9e77c/go.mod h1:K4uyk7z7BCEPqu6E+C64Yfv1cQ7kz7rIZviUmN+EgEM=
 gopkg.in/yaml.v3 v3.0.1 h1:fxVm/GzAzEWqLHuvctI91KS9hhNmmWOoWu0XTYJS7CA=