Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

Sign up for GitHub

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Jump to bottom

GO:0031073 cholesterol 26-hydroxylase activity with no cross reference #29029

Open
raymond91125 opened this issue Oct 8, 2024 · 2 comments
Open

GO:0031073 cholesterol 26-hydroxylase activity with no cross reference #29029

raymond91125 opened this issue Oct 8, 2024 · 2 comments
Assignees
@raymond91125
Labels
Catalytic activity terms with no cross references

Comments

@raymond91125
Copy link
Contributor

raymond91125 commented Oct 8, 2024 •
edited
Loading

GO:0031073 cholesterol 26-hydroxylase activity lacks a EC/RHEA cross reference.

The definition xref is PMID:950499 On the heterogeneity of the mitochondrial C27-steroid 26-hydroxylase system. This activity probably corresponds to RHEA:43836 cholesterol + H(+) + NADPH + O2 = 26-hydroxycholesterol + H2O + NADP(+).

image

However, RHEA:43836 is a general XREF for GO:0008395 steroid hydroxylase activity, which seems too broad. Move RHEA:43836 from GO:0008395 to GO:0031073.
@raymond91125 raymond91125 self-assigned this Oct 8, 2024
@github-actions github-actions bot mentioned this issue Oct 8, 2024
Merged
raymond91125 added a commit that referenced this issue Oct 8, 2024
@raymond91125
Merge pull request #29032 from geneontology/issue-29029
6b869ef 
Added RHEA xref; fixes #29029
@pgaudet
Copy link
Contributor

pgaudet commented Oct 10, 2024

Please update the definition ans prent to be consistent with RHEA.

@pgaudet pgaudet reopened this Oct 10, 2024
raymond91125 pushed a commit that referenced this issue Oct 10, 2024
@raymond91105
Changed def to match RHEA; #29029
0fcfa36
raymond91125 added a commit that referenced this issue Oct 11, 2024
@raymond91125
Merge pull request #29046 from geneontology/issue-29029
0712ebd 
Changed def to match RHEA; #29029
@raymond91125
Copy link
Contributor Author

Please update the definition ans prent to be consistent with RHEA.

Which parent should it be informed by RHEA:43836?

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Assignees

@raymond91125 raymond91125

Labels
Catalytic activity terms with no cross references
Projects
GO-EC-RHEA xref alignment
Status: In progress
Milestone
No milestone
Development

No branches or pull requests
2 participants
@raymond91125 @pgaudet