diff --git a/src/ontology/imports/go-catalytic-activities-participants.obo b/src/ontology/imports/go-catalytic-activities-participants.obo
index b61ab47975..081818134e 100644
--- a/src/ontology/imports/go-catalytic-activities-participants.obo
+++ b/src/ontology/imports/go-catalytic-activities-participants.obo
@@ -9639,16 +9639,6 @@ relationship: RO:0000057 CHEBI:15379
 relationship: RO:0000057 CHEBI:16205
 relationship: RO:0000057 CHEBI:58284
 
-[Term]
-id: GO:0018595
-relationship: RO:0000057 CHEBI:15377
-relationship: RO:0000057 CHEBI:15378
-relationship: RO:0000057 CHEBI:15379
-relationship: RO:0000057 CHEBI:28660
-relationship: RO:0000057 CHEBI:29060
-relationship: RO:0000057 CHEBI:57540
-relationship: RO:0000057 CHEBI:57945
-
 [Term]
 id: GO:0018597
 relationship: RO:0000057 CHEBI:13193
@@ -9801,6 +9791,16 @@ relationship: RO:0000057 CHEBI:57783
 relationship: RO:0000057 CHEBI:57917
 relationship: RO:0000057 CHEBI:58349
 
+[Term]
+id: GO:0018634
+relationship: RO:0000057 CHEBI:15377
+relationship: RO:0000057 CHEBI:15378
+relationship: RO:0000057 CHEBI:15379
+relationship: RO:0000057 CHEBI:28660
+relationship: RO:0000057 CHEBI:29060
+relationship: RO:0000057 CHEBI:57540
+relationship: RO:0000057 CHEBI:57945
+
 [Term]
 id: GO:0018640
 relationship: RO:0000057 CHEBI:15377
@@ -25821,6 +25821,12 @@ relationship: RO:0000057 CHEBI:15377
 relationship: RO:0000057 CHEBI:17945
 relationship: RO:0000057 CHEBI:17966
 
+[Term]
+id: GO:0050550
+relationship: RO:0000057 CHEBI:28359
+relationship: RO:0000057 CHEBI:33019
+relationship: RO:0000057 CHEBI:58057
+
 [Term]
 id: GO:0050551
 relationship: RO:0000057 CHEBI:17221
@@ -34003,6 +34009,14 @@ relationship: RO:0000057 CHEBI:59789
 relationship: RO:0000057 CHEBI:74411
 relationship: RO:0000057 CHEBI:74491
 
+[Term]
+id: GO:0160117
+relationship: RO:0000057 CHEBI:15378
+relationship: RO:0000057 CHEBI:57856
+relationship: RO:0000057 CHEBI:59789
+relationship: RO:0000057 CHEBI:74269
+relationship: RO:0000057 CHEBI:74481
+
 [Term]
 id: GO:0170003
 relationship: RO:0000057 CHEBI:60344
diff --git a/src/ontology/imports/go-catalytic-activities-participants.owl b/src/ontology/imports/go-catalytic-activities-participants.owl
index d401b6320f..bc2b7a9cfb 100644
--- a/src/ontology/imports/go-catalytic-activities-participants.owl
+++ b/src/ontology/imports/go-catalytic-activities-participants.owl
@@ -9518,6 +9518,12 @@
     
 
 
+    <!-- http://purl.obolibrary.org/obo/CHEBI_28359 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28359"/>
+    
+
+
     <!-- http://purl.obolibrary.org/obo/CHEBI_28395 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28395"/>
@@ -70088,55 +70094,6 @@
     
 
 
-    <!-- http://purl.obolibrary.org/obo/GO_0018595 -->
-
-    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0018595">
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15377"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15378"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15379"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28660"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29060"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_57540"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_57945"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-    </owl:Class>
-    
-
-
     <!-- http://purl.obolibrary.org/obo/GO_0018597 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0018597">
@@ -70873,6 +70830,55 @@
     
 
 
+    <!-- http://purl.obolibrary.org/obo/GO_0018634 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0018634">
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15377"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15378"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15379"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28660"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29060"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_57540"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_57945"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+    </owl:Class>
+    
+
+
     <!-- http://purl.obolibrary.org/obo/GO_0018640 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0018640">
@@ -144102,6 +144108,31 @@
     
 
 
+    <!-- http://purl.obolibrary.org/obo/GO_0050550 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0050550">
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28359"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33019"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_58057"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+    </owl:Class>
+    
+
+
     <!-- http://purl.obolibrary.org/obo/GO_0050551 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0050551">
@@ -182139,6 +182170,43 @@
     
 
 
+    <!-- http://purl.obolibrary.org/obo/GO_0160117 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0160117">
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15378"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_57856"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_59789"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_74269"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+        <rdfs:subClassOf>
+            <owl:Restriction>
+                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
+                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_74481"/>
+            </owl:Restriction>
+        </rdfs:subClassOf>
+    </owl:Class>
+    
+
+
     <!-- http://purl.obolibrary.org/obo/GO_0170003 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0170003">