diff --git a/docs/source/markdown/podman-systemd.unit.5.md b/docs/source/markdown/podman-systemd.unit.5.md
index 5bbc2b6974..269c7ffd3b 100644
--- a/docs/source/markdown/podman-systemd.unit.5.md
+++ b/docs/source/markdown/podman-systemd.unit.5.md
@@ -168,6 +168,7 @@ Valid options for `[Container]` are listed below:
 | Environment=foo=bar                  | --env foo=bar                                        |
 | EnvironmentFile=/tmp/env             | --env-file /tmp/env                                  |
 | EnvironmentHost=true                 | --env-host                                           |
+| Entrypoint=/foo.sh                   | --entrypoint=/foo.sh                                 |
 | Exec=/usr/bin/command                | Command after image specification - /usr/bin/command |
 | ExposeHostPort=50-59                 | --expose 50-59                                       |
 | GIDMap=0:10000:10                    | --gidmap=0:10000:10                                  |
@@ -320,6 +321,12 @@ This key may be used multiple times, and the order persists when passed to `podm
 
 Use the host environment inside of the container.
 
+#### `Entrypoint=`
+
+Override the default ENTRYPOINT from the image.
+Equivalent to the Podman `--entrypoint` option.
+Specify multi option commands in the form of a json string.
+
 ### `Exec=`
 
 If this is set then it defines what command line to run in the container. If it is not set the
diff --git a/pkg/systemd/quadlet/quadlet.go b/pkg/systemd/quadlet/quadlet.go
index 349d55bc79..c484ec66d0 100644
--- a/pkg/systemd/quadlet/quadlet.go
+++ b/pkg/systemd/quadlet/quadlet.go
@@ -72,6 +72,7 @@ const (
 	KeyEnvironment           = "Environment"
 	KeyEnvironmentFile       = "EnvironmentFile"
 	KeyEnvironmentHost       = "EnvironmentHost"
+	KeyEntrypoint            = "Entrypoint"
 	KeyExec                  = "Exec"
 	KeyExitCodePropagation   = "ExitCodePropagation"
 	KeyExposeHostPort        = "ExposeHostPort"
@@ -180,6 +181,7 @@ var (
 		KeyEnvironment:           true,
 		KeyEnvironmentFile:       true,
 		KeyEnvironmentHost:       true,
+		KeyEntrypoint:            true,
 		KeyExec:                  true,
 		KeyExposeHostPort:        true,
 		KeyGIDMap:                true,
@@ -628,6 +630,11 @@ func ConvertContainer(container *parser.UnitFile, names map[string]string, isUse
 		podman.addf("--shm-size=%s", shmSize)
 	}
 
+	entrypoint, hasEntrypoint := container.Lookup(ContainerGroup, KeyEntrypoint)
+	if hasEntrypoint {
+		podman.addf("--entrypoint=%s", entrypoint)
+	}
+
 	sysctl := container.LookupAllStrv(ContainerGroup, KeySysctl)
 	for _, sysctlItem := range sysctl {
 		podman.addf("--sysctl=%s", sysctlItem)
diff --git a/test/e2e/quadlet/entrypoint.container b/test/e2e/quadlet/entrypoint.container
new file mode 100644
index 0000000000..035783500b
--- /dev/null
+++ b/test/e2e/quadlet/entrypoint.container
@@ -0,0 +1,6 @@
+## assert-podman-final-args localhost/imagename
+## assert-podman-args "--entrypoint=top"
+
+[Container]
+Image=localhost/imagename
+Entrypoint=top
diff --git a/test/e2e/quadlet_test.go b/test/e2e/quadlet_test.go
index a89107e13d..a4e76edccb 100644
--- a/test/e2e/quadlet_test.go
+++ b/test/e2e/quadlet_test.go
@@ -765,6 +765,7 @@ BOGUS=foo
 		Entry("env-host-false.container", "env-host-false.container", 0, ""),
 		Entry("env-host.container", "env-host.container", 0, ""),
 		Entry("env.container", "env.container", 0, ""),
+		Entry("entrypoint.container", "entrypoint.container", 0, ""),
 		Entry("escapes.container", "escapes.container", 0, ""),
 		Entry("exec.container", "exec.container", 0, ""),
 		Entry("health.container", "health.container", 0, ""),