Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

[Feature request] option to filter alignments based on annotation type #37

Open
elhossary opened this issue Oct 14, 2021 · 0 comments
Open

Comments

@elhossary
Copy link

Option to filter alignments based on annotation type, for example, RNA-Seq can contain ribosomal RNA reads. if no proper rRNA depletion was done to the sample, they can be the majority of the reads. Thus, when aligned, and coverage computed based on their presence, the can affect the normalization. So, In some use cases they need to be removed from the alignment before coverage generation.
This can be easily aceived by "bedtools intersect" which accepts BAM files as will as GFFs and can be used to filter them

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant