build_model with continous fixed effect

[nomascus]

Hi,

Is it possible to use build_model with strategy_lmer when the fixed effect is a continuous rather than categorical variable? Ultimately, I would like to generate an aovtable (aovtable <- mod$get_anova()) that I can use for GSEA.

For example, I would like to use the age of the individual to predict protein intensity. I don't have a problem with the downstream analysis when I used age as a categorical variable (i.e. setting up a contrast of young vs old) with strategy_lmer, but build_model seems to break when I use the actual age in months of the individual.

Thanks!

[wolski]

Have you tried it, and it did not work? The model fitting and the ANOVA should work. I need help understanding how you can use the ANOVA results for GSEA.