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Reference index file is not optional for Manta #48

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davidcotter opened this issue Jan 31, 2019 · 1 comment
Open

Reference index file is not optional for Manta #48

davidcotter opened this issue Jan 31, 2019 · 1 comment

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@davidcotter
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davidcotter commented Jan 31, 2019

The documentation states that the index for the reference is optional:
--fai FAI (Optional) The name of the corresponding index for the reference genome file.

For Manta at least, if I omit the index, this caused it to fail with the following error message:

Usage: configManta.py [options]
configManta.py: error: Can't find expected fasta index file: '/home/dnanexus/ref.fa.fai'
python: can't open file '/home/dnanexus/manta/runWorkflow.py': [Errno 2] No such file or directory

If I include the reference index Manta runs. Perhaps this could be a mandatory parameter or the index could be generated.

I am using the docker image dnanexus/parliament2

Thanks.

@slzarate
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slzarate commented Feb 6, 2019

Hi @davidcotter, let me look into this, as the FAI should be generated automatically if not included. Thanks for using Parliament2!

Also, can you use the Docker image dnanexus/parliament2:0.1.9? That's the latest version.

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