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NB.1 + S:Q493E (14 samples 5 places) with a S:A435S branch (4, UK,HK, Liaoning,Thailand), and a separate singlet with S:F490S from Gansu #2905

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FedeGueli opened this issue Mar 3, 2025 · 4 comments

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@FedeGueli
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First proposed in sars-cov-2-variants/lineage-proposals#2431

NB.1 got S:Q493E and this is relevant, but it is even more relevant because it got further S:A435S in a 4 sequences branch from 4 different places.
To be noticed that a singlet from Gansu has instead S:F490S

NB.1>> ORF1b:D275Y (G14290T) > C5878T > C823T, G2095A, S:Q493E (C23039G) > C15960T, S:A435S (G22865T)
Query:C823T, G2095A, C23039G
Query for 435S sample: C823T, G2095A, G22865T
Query for 490S sample: C823T, G2095A, T23031C

Samples: 10
First collected on 2025-01-09 in Liaoning
Places:
HK,Uk, Liaoning, Thailand with 435S ,
Gansu with 490S

Tree:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/hgPhyloPlace/subtreeAuspice1_genome_2814ee_601990.json?label=id:node_7502588
Image

Samples:
EPI_ISL_19706088, EPI_ISL_19734798, EPI_ISL_19743992-19743994,
EPI_ISL_19750627, EPI_ISL_19756603, EPI_ISL_19756613-19756614,
EPI_ISL_19757519

Ping @corneliusroemer it seems expanding fast .

@HynnSpylor
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XDV* lineages has become the dominant variants in China since more than half years ago. NB.1* has got S:T22N, now the convergent to Q493E, A435S is very interesting and worth tracking.

@HynnSpylor
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+3 in NSW, Australia
It should be concerned.

@FedeGueli FedeGueli changed the title NB.1 + S:Q493E (10 samples 4 places) with a S:A435S branch (4, UK,HK, Liaoning,Thailand), and a separate singlet with S:F490S from Gansu NB.1 + S:Q493E (13 samples 5 places) with a S:A435S branch (4, UK,HK, Liaoning,Thailand), and a separate singlet with S:F490S from Gansu Mar 6, 2025
@FedeGueli
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ping @corneliusroemer expanding fast

@HynnSpylor
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+1 Gansu, China

@FedeGueli FedeGueli changed the title NB.1 + S:Q493E (13 samples 5 places) with a S:A435S branch (4, UK,HK, Liaoning,Thailand), and a separate singlet with S:F490S from Gansu NB.1 + S:Q493E (14 samples 5 places) with a S:A435S branch (4, UK,HK, Liaoning,Thailand), and a separate singlet with S:F490S from Gansu Mar 7, 2025
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