diff --git a/apiv2/database/models/tomogram_voxel_spacing.py b/apiv2/database/models/tomogram_voxel_spacing.py
index 304e1b5f..7e5c1f8b 100644
--- a/apiv2/database/models/tomogram_voxel_spacing.py
+++ b/apiv2/database/models/tomogram_voxel_spacing.py
@@ -38,6 +38,7 @@ class TomogramVoxelSpacing(Base):
         back_populates="tomogram_voxel_spacing",
         uselist=True,
         foreign_keys="AnnotationFile.tomogram_voxel_spacing_id",
+        cascade="all, delete-orphan",
     )
     run_id: Mapped[int] = mapped_column(Integer, ForeignKey("run.id"), nullable=True, index=True)
     run: Mapped["Run"] = relationship(
diff --git a/apiv2/schema/schema.yaml b/apiv2/schema/schema.yaml
index e1f45854..e1e1dc4f 100644
--- a/apiv2/schema/schema.yaml
+++ b/apiv2/schema/schema.yaml
@@ -2203,6 +2203,8 @@ classes:
         multivalued: true
         inverse: AnnotationFile.tomogram_voxel_spacing
         range: AnnotationFile
+        annotations:
+          cascade_delete: true
       run:
         name: run
         from_schema: cdp-dataset-config