This package takes in DESeq2 output. To upload an excel file as a usable dataframe install the following package
install.packages("readxl")
Load the package
library ("readxl")
Usage for the first sheet in an .xls file
df <- read_excel("~/path/to/file.xls")
Usage if you wish to reference a specific sheet
df <- read_excel("~/path/to/file.xls", sheet = 2)