Description
This is https://bugs.kde.org/show_bug.cgi?id=396415 , but opening it here just for tracking/visibility. When running a script under valgrind mis-reports /proc/self/exe as the path to the script itself instead of the path to the script interpreter. This means that, at least on glibc/Linux, the $ORIGIN-relative library paths that are used by python-build-standalone don't get resolved correctly for scripts installed in a different directory to the Python interpreter (notably, those installed in a venv), and the Python interpreter fails to launch.
The minimal reproduction is something like valgrind --tool=none some/venv/bin/pytest (or just plain valgrind).
This was reported specifically as codspeed run pytest (invoked by CodSpeedHQ/action in GHA) not working. CodSpeed internally uses valgrind.
A workaround is to invoke the interpreter directly instead of using a script, either with an appropriate python -m command (e.g. python -m pytest), or by passing the script as an argument to the interpreter (e.g., python some/venv/bin/pytest).