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Very powerful and effective tools for single cell methylation data analysis, but I wonder if you have consider the batch efforts across different library, and how to remove batch effort through MethSCAn. I think it will be nice if you could supply some strategy which could help to remove batch efforts based on MethSCAn.
Kinds regards,
Hengbin
The text was updated successfully, but these errors were encountered:
this is a great question but unfortunately I don't have a satisfying answer. In principle it should be possible to adapt one of the many batch correction or integration methods from single-cell RNA-seq to single-cell methylation data. However I have never tried this, so I'm not sure how easy it would be. I will let you know if I ever find out how to do this!
Lukas
Hi anders,
Very powerful and effective tools for single cell methylation data analysis, but I wonder if you have consider the batch efforts across different library, and how to remove batch effort through MethSCAn. I think it will be nice if you could supply some strategy which could help to remove batch efforts based on MethSCAn.
Kinds regards,
Hengbin
The text was updated successfully, but these errors were encountered: