diff --git a/lib/experimental/add-registered-webfonts-to-theme-json.php b/lib/experimental/add-registered-webfonts-to-theme-json.php
index a859b0c1edc036..14039aaa947524 100644
--- a/lib/experimental/add-registered-webfonts-to-theme-json.php
+++ b/lib/experimental/add-registered-webfonts-to-theme-json.php
@@ -1,10 +1,14 @@
 <?php
 
-function gutenberg_is_webfont_equal( $a, $b ) {
-	$equality_attrs = array(
+function gutenberg_is_webfont_equal( $a, $b, $is_camel_case = true ) {
+	$equality_attrs = $is_camel_case ? array(
 		'fontFamily',
 		'fontStyle',
 		'fontWeight',
+	) : array(
+		'font-family',
+		'font-style',
+		'font-weight',
 	);
 
 	foreach ( $equality_attrs as $attr ) {
@@ -17,8 +21,14 @@ function gutenberg_is_webfont_equal( $a, $b ) {
 }
 
 function gutenberg_find_webfont( $webfonts, $webfont_to_find ) {
+	if ( ! count( $webfonts ) ) {
+		return false;
+	}
+
+	$is_camel_case = isset( $webfonts[0]['fontFamily'] );
+
 	foreach ( $webfonts as $index => $webfont ) {
-		if ( gutenberg_is_webfont_equal( $webfont, $webfont_to_find ) ) {
+		if ( gutenberg_is_webfont_equal( $webfont, $webfont_to_find, $is_camel_case ) ) {
 			return $index;
 		}
 	}
diff --git a/lib/experimental/class-wp-webfonts.php b/lib/experimental/class-wp-webfonts.php
index d4a73c77cc2d2d..e1cb151075377b 100644
--- a/lib/experimental/class-wp-webfonts.php
+++ b/lib/experimental/class-wp-webfonts.php
@@ -145,13 +145,14 @@ public function register_webfont( array $webfont ) {
 	/**
 	 * Enqueue a font-family that has been already registered.
 	 *
-	 * @param string $font_family_name The font family name to be enqueued.
+	 * @param string     $font_family_name The font family name to be enqueued.
+	 * @param array|null $font_face The font face to selectively enqueue.
 	 * @return bool True if successfully enqueued, else false.
 	 */
-	public function enqueue_webfont( $font_family_name ) {
+	public function enqueue_webfont( $font_family_name, $font_face = null ) {
 		$slug = $this->get_font_slug( $font_family_name );
 
-		if ( isset( $this->enqueued_webfonts[ $slug ] ) ) {
+		if ( isset( $this->enqueued_webfonts[ $slug ] ) && ! isset( $this->registered_webfonts[ $slug ] ) ) {
 			trigger_error(
 				sprintf(
 					/* translators: %s unique slug to identify the font family of the webfont */
@@ -170,11 +171,50 @@ public function enqueue_webfont( $font_family_name ) {
 			return false;
 		}
 
-		$this->enqueued_webfonts[ $slug ] = $this->registered_webfonts[ $slug ];
-		unset( $this->registered_webfonts[ $slug ] );
+		if ( ! $font_face ) {
+			$font_family_to_enqueue           = $this->unregister_font_family( $font_family_name );
+			$this->enqueued_webfonts[ $slug ] = $font_family_to_enqueue;
+
+			return true;
+		}
+
+		$font_face            = gutenberg_webfont_to_kebab_case( $font_face );
+		$font_face_to_enqueue = $this->unregister_font_face( $font_face );
+
+		if ( ! $font_face_to_enqueue ) {
+			trigger_error(
+				sprintf(
+					__( 'The "%1$s:%2$s:%3$s" font face is not registered.', 'gutenberg' ),
+					$font_face['font-family'],
+					$font_face['font-weight'],
+					$font_face['font-style']
+				)
+			);
+
+			return false;
+		}
+
+		if ( ! isset( $this->enqueued_webfonts[ $slug ] ) ) {
+			$this->enqueued_webfonts[ $slug ] = array();
+		}
+
+		$this->enqueued_webfonts[ $slug ][] = $font_face_to_enqueue;
+
 		return true;
 	}
 
+	/**
+	 * Checks if a font family is registered.
+	 *
+	 * @param string $font_family_name The font family name to check in the registry.
+	 * @return bool True if found, else false.
+	 */
+	public function is_font_family_registered( $font_family_name ) {
+		$slug = $this->get_font_slug( $font_family_name );
+
+		return isset( $this->registered_webfonts[ $slug ] );
+	}
+
 	/**
 	 * Get the font slug.
 	 *
@@ -199,6 +239,41 @@ public static function get_font_slug( $to_convert ) {
 		return sanitize_title( $to_convert );
 	}
 
+	public function unregister_font_family( $font_family_name ) {
+		$slug = $this->get_font_slug( $font_family_name );
+
+		if ( ! isset( $this->registered_webfonts[ $slug ] ) ) {
+			return false;
+		}
+
+		$font_family = $this->registered_webfonts[ $slug ];
+		unset( $this->registered_webfonts[ $slug ] );
+
+		return $font_family;
+	}
+
+	public function unregister_font_face( $font_face_to_unregister ) {
+		$font_family_slug = $this->get_font_slug( $font_face_to_unregister );
+
+		$font_family = $this->registered_webfonts[ $font_family_slug ];
+		$index       = gutenberg_find_webfont( $font_family, $font_face_to_unregister );
+
+		// Font face not found.
+		if ( false === $index ) {
+			return false;
+		}
+
+		$font_face = $this->registered_webfonts[ $font_family_slug ][ $index ];
+		unset( $this->registered_webfonts[ $font_family_slug ][ $index ] );
+
+		// No font faces left, let's remove the font family entry.
+		if ( 0 === count( $this->registered_webfonts[ $font_family_slug ] ) ) {
+			unset( $this->registered_webfonts[ $font_family_slug ] );
+		}
+
+		return $font_face;
+	}
+
 	/**
 	 * Validate a webfont.
 	 *
diff --git a/lib/experimental/enqueue-webfonts-listed-in-theme-json.php b/lib/experimental/enqueue-webfonts-listed-in-theme-json.php
new file mode 100644
index 00000000000000..e067ebe796164c
--- /dev/null
+++ b/lib/experimental/enqueue-webfonts-listed-in-theme-json.php
@@ -0,0 +1,56 @@
+<?php
+
+function gutenberg_is_externally_registered_webfont( $webfont ) {
+	return isset( $webfont['origin'] ) && 'gutenberg_wp_webfonts_api' === $webfont['origin'];
+}
+
+function gutenberg_enqueue_webfonts_listed_in_theme_json() {
+	$theme_settings = WP_Theme_JSON_Resolver_Gutenberg::get_theme_data()->get_settings();
+
+	// Bail out early if there are no settings for webfonts.
+	if ( empty( $theme_settings['typography'] ) || empty( $theme_settings['typography']['fontFamilies'] ) ) {
+		return;
+	}
+
+	// Look for fontFamilies.
+	foreach ( $theme_settings['typography']['fontFamilies'] as $font_families ) {
+		foreach ( $font_families as $font_family ) {
+			// Skip dynamically included font families. We only want to enqueue explicitly added fonts.
+			if ( gutenberg_is_externally_registered_webfont( $font_family ) ) {
+				continue;
+			}
+
+			// If no font faces defined.
+			if ( ! isset( $font_family['fontFaces'] ) ) {
+				// And the font family is registered.
+				if ( ! wp_webfonts()->is_font_family_registered( $font_family['fontFamily'] ) ) {
+					continue;
+				}
+
+				// Enqueue the entire family.
+				wp_webfonts()->enqueue_webfont( $font_family );
+				continue;
+			}
+
+			// Loop through all the font faces, enqueueing each one of them.
+			foreach ( $font_family['fontFaces'] as $font_face ) {
+				// Skip dynamically included font faces. We only want to enqueue the font faces listed in theme.json.
+				if ( gutenberg_is_externally_registered_webfont( $font_face ) ) {
+					continue;
+				}
+
+				wp_webfonts()->enqueue_webfont( $font_family, $font_face );
+			}
+		}
+	}
+}
+
+add_filter( 'wp_loaded', 'gutenberg_enqueue_webfonts_listed_in_theme_json' );
+
+// No need to run this -- opening the admin interface enqueues all the webfonts.
+add_action(
+	'admin_init',
+	function() {
+		remove_filter( 'wp_loaded', 'gutenberg_enqueue_webfonts_listed_in_theme_json' );
+	}
+);
diff --git a/lib/load.php b/lib/load.php
index 568a00a63e0f77..2a45026fca7a42 100644
--- a/lib/load.php
+++ b/lib/load.php
@@ -109,6 +109,7 @@ function gutenberg_is_experiment_enabled( $name ) {
 require __DIR__ . '/compat/wordpress-6.0/edit-form-blocks.php';
 require __DIR__ . '/experimental/register-webfonts-from-theme-json.php';
 require __DIR__ . '/experimental/add-registered-webfonts-to-theme-json.php';
+require __DIR__ . '/experimental/enqueue-webfonts-listed-in-theme-json.php';
 require __DIR__ . '/experimental/class-wp-theme-json-resolver-gutenberg.php';
 require __DIR__ . '/experimental/class-wp-webfonts.php';
 require __DIR__ . '/experimental/class-wp-webfonts-provider.php';