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Releases: TRON-Bioinformatics/covigator-ngs-pipeline

Release Covigator NGS pipeline v0.3.0

15 Jun 20:30
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Major changes

  • Add read trimming with fastp
  • Output QC results in JSON format
  • Integrate 4 variants callers: BCFtools, iVar, GATK and LoFreq
  • Include soft filtering of variants based on VAF for all variants from LoFreq and for indels from BCFtools
  • Integrate SnpEff 5.0 for the variant annotation
  • Parametrize some quality thresholds

Covigator NGS pipeline v0.2.0 BETA

07 Jun 13:31
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Pre-release

First pre-release integrating alignment, mark duplicates, realignment around indels, variant calling with samtools, variant normalization and variant annotations with bcftools csq.