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solution_full.txt
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============================================
=========== found ===========
============================================
============================================
=========== modules ===========
============================================
ENTRY M00377 Pathway Module
NAME Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
DEFINITION K00198 K05299-K15022 K01938 K01491 K00297 K15023 K14138+K00197+K00194
ORTHOLOGY K00198 carbon-monoxide dehydrogenase [EC:1.2.7.4] [RN:R07157]
K05299,K15022 formate dehydrogenase [EC:1.17.1.10] [RN:R00134]
K01938 formate--tetrahydrofolate ligase [EC:6.3.4.3] [RN:R00943]
K01491 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] [RN:R01655 R01220]
K00297 methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20] [RN:R07168]
K15023 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258] [RN:R02289]
K14138 acetyl-CoA synthase [EC:2.3.1.169] [RN:R08433]
K00197+K00194 acetyl-CoA decarbonylase/synthase complex [EC:2.3.1.-] [RN:R10243]
CLASS Pathway module; Energy metabolism; Carbon fixation
Signature module; Module set; Metabolic capacity;
PATHWAY map00720 Carbon fixation pathways in prokaryotes
map01200 Carbon metabolism
map01100 Metabolic pathways
map01120 Microbial metabolism in diverse environments
REACTION R07157 C00011 -> C00237
R00134 C00011 -> C00058
R00943 C00058 + C00101 -> C00234
R01655 C00234 -> C00445
R01220 C00445 -> C00143
R07168 C00143 -> C00440
R02289+R08433,R10243 C00237 + C00440 -> C00101 + C00024
COMPOUND C00011 CO2
C00237 CO
C00058 Formate
C00101 Tetrahydrofolate
C00234 10-Formyltetrahydrofolate
C00445 5,10-Methenyltetrahydrofolate
C00143 5,10-Methylenetetrahydrofolate
C00440 5-Methyltetrahydrofolate
C00024 Acetyl-CoA
REFERENCE PMID:3096193
AUTHORS Ljungdahl LG
TITLE The autotrophic pathway of acetate synthesis in acetogenic bacteria.
JOURNAL Annu Rev Microbiol 40:415-50 (1986)
DOI:10.1146/annurev.mi.40.100186.002215
///
============================================
=========== reactions ===========
============================================
ENTRY R07157 Reaction
NAME carbon-monoxide,water:ferredoxin oxidoreductase
DEFINITION CO + H2O + 2 Oxidized ferredoxin <=> CO2 + 2 Reduced ferredoxin + 2 H+
EQUATION C00237 + C00001 + 2 C00139 <=> C00011 + 2 C00138 + 2 C00080
RCLASS RC02800 C00011_C00237
ENZYME 1.2.7.4
PATHWAY rn00680 Methane metabolism
rn00720 Carbon fixation pathways in prokaryotes
rn01100 Metabolic pathways
rn01120 Microbial metabolism in diverse environments
rn01200 Carbon metabolism
MODULE M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
M00422 Acetyl-CoA pathway, CO2 => acetyl-CoA
ORTHOLOGY K00192 anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4]
K00195 anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit epsilon
K00196 anaerobic carbon-monoxide dehydrogenase iron sulfur subunit
K00198 anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
DBLINKS RHEA: 21043
///
ENTRY R00134 Reaction
NAME formate:NADP+ oxidoreductase
DEFINITION Formate + NADP+ <=> CO2 + NADPH + H+
EQUATION C00058 + C00006 <=> C00011 + C00005 + C00080
RCLASS RC00001 C00005_C00006
RC02796 C00011_C00058
ENZYME 1.17.1.10
PATHWAY rn00680 Methane metabolism
rn00720 Carbon fixation pathways in prokaryotes
rn01100 Metabolic pathways
rn01120 Microbial metabolism in diverse environments
rn01200 Carbon metabolism
MODULE M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
ORTHOLOGY K05299 formate dehydrogenase (NADP+) alpha subunit [EC:1.17.1.10]
K15022 formate dehydrogenase (NADP+) beta subunit [EC:1.17.1.10]
DBLINKS RHEA: 12003
///
ENTRY R00943 Reaction
NAME Formate:tetrahydrofolate ligase (ADP-forming)
DEFINITION Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate
EQUATION C00101 + C00058 + C00002 <=> C00008 + C00009 + C00234
RCLASS RC00002 C00002_C00008
RC00026 C00101_C00234
RC00111 C00058_C00234
ENZYME 6.3.4.3
PATHWAY rn00670 One carbon pool by folate
rn00720 Carbon fixation pathways in prokaryotes
rn01100 Metabolic pathways
rn01120 Microbial metabolism in diverse environments
rn01200 Carbon metabolism
MODULE M00140 C1-unit interconversion, prokaryotes
M00141 C1-unit interconversion, eukaryotes
M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
ORTHOLOGY K00288 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
K01938 formate--tetrahydrofolate ligase [EC:6.3.4.3]
K13402 monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]
DBLINKS RHEA: 20224
///
ENTRY R01655 Reaction
NAME 5,10-Methenyltetrahydrofolate 5-hydrolase (decyclizing)
DEFINITION 5,10-Methenyltetrahydrofolate + H2O <=> 10-Formyltetrahydrofolate + H+
EQUATION C00445 + C00001 <=> C00234 + C00080
RCLASS RC00578 C00234_C00445
ENZYME 3.5.4.9
PATHWAY rn00670 One carbon pool by folate
rn00720 Carbon fixation pathways in prokaryotes
rn01100 Metabolic pathways
rn01120 Microbial metabolism in diverse environments
rn01200 Carbon metabolism
MODULE M00140 C1-unit interconversion, prokaryotes
M00141 C1-unit interconversion, eukaryotes
M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
ORTHOLOGY K00288 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
K01491 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
K01500 methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9]
K13403 methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
DBLINKS RHEA: 23703
///
ENTRY R01220 Reaction
NAME 5,10-methylenetetrahydrofolate:NADP+ oxidoreductase
DEFINITION 5,10-Methylenetetrahydrofolate + NADP+ <=> 5,10-Methenyltetrahydrofolate + NADPH
EQUATION C00143 + C00006 <=> C00445 + C00005
RCLASS RC00001 C00005_C00006
RC00202 C00143_C00445
ENZYME 1.5.1.5
PATHWAY rn00670 One carbon pool by folate
rn00720 Carbon fixation pathways in prokaryotes
rn01100 Metabolic pathways
rn01120 Microbial metabolism in diverse environments
rn01200 Carbon metabolism
MODULE M00140 C1-unit interconversion, prokaryotes
M00141 C1-unit interconversion, eukaryotes
M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
ORTHOLOGY K00288 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
K00300 methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+) [EC:1.5.1.5 1.5.1.-]
K01491 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
DBLINKS RHEA: 22815
///
ENTRY R07168 Reaction
NAME 5-methyltetrahydrofolate:NAD+ oxidoreductase
DEFINITION 5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
EQUATION C00440 + C00003 <=> C00143 + C00004 + C00080
RCLASS RC00001 C00003_C00004
RC00081 C00143_C00440
ENZYME 1.5.1.20
PATHWAY rn00670 One carbon pool by folate
rn00720 Carbon fixation pathways in prokaryotes
rn01100 Metabolic pathways
rn01120 Microbial metabolism in diverse environments
rn01200 Carbon metabolism
MODULE M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
ORTHOLOGY K00297 methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]
DBLINKS RHEA: 19824
///
ENTRY R10243 Reaction
DEFINITION Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO
EQUATION C00101 + C00024 <=> C00440 + C00010 + C00237
COMMENT two-step reaction (see R08433+R02289)
RCLASS RC00004 C00010_C00024
RC00113 C00101_C00440
RC02963 C00024_C00237
RC02977 C00024_C00440
ENZYME 2.1.1.258 2.3.1.169
PATHWAY rn00720 Carbon fixation pathways in prokaryotes
rn01100 Metabolic pathways
rn01120 Microbial metabolism in diverse environments
rn01200 Carbon metabolism
MODULE M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
ORTHOLOGY K00194 acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
K00197 acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
K14138 acetyl-CoA synthase [EC:2.3.1.169]
K15023 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258]
///
============================================
=========== enzymes ===========
============================================
ENTRY EC 1.2.7.4 Enzyme
NAME anaerobic carbon-monoxide dehydrogenase;
Ni-CODH;
carbon-monoxide dehydrogenase (ferredoxin)
CLASS Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With an iron-sulfur protein as acceptor
SYSNAME carbon-monoxide,water:ferredoxin oxidoreductase
REACTION CO + H2O + 2 oxidized ferredoxin = CO2 + 2 reduced ferredoxin + 2 H+ [RN:R07157]
ALL_REAC R07157;
(other) R08034 R09317
SUBSTRATE CO [CPD:C00237];
H2O [CPD:C00001];
oxidized ferredoxin [CPD:C00139]
PRODUCT CO2 [CPD:C00011];
reduced ferredoxin [CPD:C00138];
H+ [CPD:C00080]
COMMENT This prokaryotic enzyme catalyses the reversible reduction of CO2 to CO. The electrons are transferred to redox proteins such as ferredoxin. In purple sulfur bacteria and methanogenic archaea it catalyses the oxidation of CO to CO2, which is incorporated by the Calvin-Benson-Basham cycle or released, respectively. In acetogenic and sulfate-reducing microbes it catalyses the reduction of CO2 to CO, which is incorporated into acetyl CoA by EC 2.3.1.169, CO-methylating acetyl CoA synthase, with which the enzyme forms a tight complex in those organisms. The enzyme contains five metal clusters per homodimeric enzyme: two nickel-iron-sulfur clusters called the C-Clusters, one [4Fe-4S] D-cluster; and two [4Fe-4S] B-clusters. In methanogenic archaea additional [4Fe-4S] clusters exist, presumably as part of the electron transfer chain. In purple sulfur bacteria the enzyme forms complexes with the Ni-Fe-S protein EC 1.12.7.2, ferredoxin hydrogenase, which catalyse the overall reaction: CO + H2O = CO2 + H2. cf. EC 1.2.5.3, aerobic carbon monoxide dehydrogenase.
HISTORY EC 1.2.7.4 created 2003 (EC 1.2.99.2 created 1982, modified 1990, modified 2003, incorporated 2015), modified 2016
REFERENCE 1 [PMID:6687389]
AUTHORS Ragsdale SW, Clark JE, Ljungdahl LG, Lundie LL, Drake HL.
TITLE Properties of purified carbon monoxide dehydrogenase from Clostridium thermoaceticum, a nickel, iron-sulfur protein.
JOURNAL J Biol Chem 258:2364-9 (1983)
REFERENCE 2 [PMID:6687458]
AUTHORS Diekert G, Ritter M.
TITLE Purification of the nickel protein carbon monoxide dehydrogenase of Clostridium thermoaceticum.
JOURNAL FEBS Lett 151:41-4 (1983)
DOI:10.1016/0014-5793(83)80338-X
REFERENCE 3 [PMID:3029096]
AUTHORS Bonam D, Ludden PW.
TITLE Purification and characterization of carbon monoxide dehydrogenase, a nickel, zinc, iron-sulfur protein, from Rhodospirillum rubrum.
JOURNAL J Biol Chem 262:2980-7 (1987)
REFERENCE 4 [PMID:11593006]
AUTHORS Drennan CL, Heo J, Sintchak MD, Schreiter E, Ludden PW.
TITLE Life on carbon monoxide: X-ray structure of Rhodospirillum rubrum Ni-Fe-S carbon monoxide dehydrogenase.
JOURNAL Proc Natl Acad Sci U S A 98:11973-8 (2001)
DOI:10.1073/pnas.211429998
SEQUENCE [rru:Rru_A1427]
REFERENCE 5 [PMID:11509720]
AUTHORS Dobbek H, Svetlitchnyi V, Gremer L, Huber R, Meyer O.
TITLE Crystal structure of a carbon monoxide dehydrogenase reveals a [Ni-4Fe-5S] cluster.
JOURNAL Science 293:1281-5 (2001)
DOI:10.1126/science.1061500
SEQUENCE [chy:CHY_0085]
REFERENCE 6 [PMID:12386327]
AUTHORS Doukov TI, Iverson TM, Seravalli J, Ragsdale SW, Drennan CL.
TITLE A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase.
JOURNAL Science 298:567-72 (2002)
DOI:10.1126/science.1075843
SEQUENCE [mta:Moth_1203]
REFERENCE 7 [PMID:24521136]
AUTHORS Can M, Armstrong FA, Ragsdale SW
TITLE Structure, function, and mechanism of the nickel metalloenzymes, CO dehydrogenase, and acetyl-CoA synthase.
JOURNAL Chem Rev 114:4149-74 (2014)
DOI:10.1021/cr400461p
PATHWAY ec00633 Nitrotoluene degradation
ec00680 Methane metabolism
ec00720 Carbon fixation pathways in prokaryotes
ec01100 Metabolic pathways
ec01120 Microbial metabolism in diverse environments
ORTHOLOGY K00192 anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha
K00198 anaerobic carbon-monoxide dehydrogenase catalytic subunit
GENES CAMA: F384_12620
AVN: Avin_04490(cooS)
AVL: AvCA_04490(cooS)
AVD: AvCA6_04490(cooS)
ACX: Achr_4450(cooS)
TMB: Thimo_0223
CCV: CCV52592_1131(codH)
CCO: CCC13826_0236(codH)
CGRA: CGRAC_1999
GSU: GSU2098(cooS)
GME: Gmet_1902(cooS)
GUR: Gura_0618
GBM: Gbem_0072(cooS-2) Gbem_1736(cooS-1)
GEO: Geob_0362(cooS-1) Geob_1046(cooS-2)
GPI: GPICK_01000 GPICK_11385
GSB: GSUB_09760
PCA: Pcar_0057(cooS-2) Pcar_0888(cooS-1)
PEF: A7E78_09750
DES: DSOUD_1182(cooS)
DEU: DBW_0138
DVU: DVU2098(cooS)
DVL: Dvul_1133
DVM: DvMF_2233
DVG: Deval_1949
DDE: Dde_3028
DDS: Ddes_0382
DDN: DND132_2520
DMA: DMR_25780
DSA: Desal_2508
DAF: Desaf_2842
DEF: CNY67_12835(cooS)
DFL: DFE_2686
DAS: Daes_0529
DPI: BN4_11760(cooS) BN4_20190(cooS)
DEJ: AWY79_01565 AWY79_06530 AWY79_06540
PPRF: DPRO_1606(cooS) DPRO_3530
DBA: Dbac_0934
DRT: Dret_1234
DAK: DaAHT2_0337 DaAHT2_0827
DSF: UWK_01293 UWK_03164
DOL: Dole_1461 Dole_3185
DML: Dmul_09300(cooS1) Dmul_19100(cooS2) Dmul_30840(cdhA)
DAL: Dalk_0680 Dalk_2379
DAT: HRM2_16670(cdhA) HRM2_41010(cdh1) HRM2_43440(cdh2)
DTO: TOL2_C00990(cdh1) TOL2_C11820(cdhA) TOL2_C38110(cooS)
DAO: Desac_0166 Desac_1966 Desac_2050
DTI: Desti_0232
SFU: Sfum_2566 Sfum_2875
DBR: Deba_0241
RPC: RPC_4498
RRU: Rru_A1427
RRF: F11_07370
BBEV: BBEV_2326(cooS1)
GMC: GY4MC1_1807
GTH: Geoth_1875
PTL: AOT13_13405
PDU: PDUR_14040
CAC: CA_C0116 CA_C2498
CAE: SMB_G0117(cooS) SMB_G2533
CAY: CEA_G0117 CEA_G2512
CTC: CTC_01156
CTET: BN906_01229
CNO: NT01CX_0669(cooS)
CBO: CBO1331 CBO2218
CBA: CLB_1359 CLB_2157
CBH: CLC_1369
CBY: CLM_1506 CLM_2421
CBL: CLK_0775 CLK_1658
CBB: CLD_2358 CLD_3226
CBI: CLJ_B1446 CLJ_B2428
CBN: CbC4_2402(cooS)
CBF: CLI_1426 CLI_2267
CBM: CBF_1402 CBF_2255
CBJ: H04402_01401 H04402_02230
CBE: Cbei_3020 Cbei_5054
CBZ: Cbs_3020 Cbs_5054
CBEI: LF65_03401 LF65_05731
CKL: CKL_2148
CKR: CKR_1887
CLJ: CLJU_c09110(cooS1) CLJU_c17910(cooS2) CLJU_c37670(codH)
CCB: Clocel_0365 Clocel_1516 Clocel_2587 Clocel_4231
CLB: Clo1100_1430 Clo1100_3687
CSR: Cspa_c16740(cooS1) Cspa_c21120(cooS2) Cspa_c57670(cooS3)
CPAS: Clopa_0057 Clopa_1484 Clopa_2128 Clopa_3232
CPAT: CLPA_c05080(cooS) CLPA_c34390(cooS1)
CPAE: CPAST_c05080(cooS) CPAST_c34390(cooS1)
CSB: CLSA_c11710(cooS1) CLSA_c14830(cooS2)
CAH: CAETHG_1620 CAETHG_1621 CAETHG_3005 CAETHG_3899
CLT: CM240_0400
CSQ: CSCA_1153 CSCA_1513 CSCA_1514 CSCA_3645 CSCA_4539
CLD: CLSPO_c13520(cooS1) CLSPO_c22620(cooS2)
CACE: CACET_c09110(acsA1) CACET_c10200(acsA2) CACET_c16200 CACET_c26140(acsA3)
CCK: Ccar_07140 Ccar_08590 Ccar_18845 Ccar_23090
CTYK: CTK_C21760(cooS)
CEU: A7L45_14975
CFM: BJL90_04040 BJL90_08730 BJL90_10555 BJL90_11075 BJL90_13810 BJL90_18885
CARG: RSJ17_07130 RSJ17_07755
CDRK: B9W14_01390 B9W14_11700 B9W14_13030 B9W14_22310
AMT: Amet_1177 Amet_2016 Amet_3764
GFE: Gferi_05255 Gferi_06375 Gferi_11835 Gferi_24855
CTH: Cthe_2801
CTX: Clo1313_0390
CCL: Clocl_0520 Clocl_0806
CCE: Ccel_0438 Ccel_2918
CSS: Cst_c19650(cooS1)
CSD: Clst_1883
CTHD: CDO33_08275(cooS)
RAL: Rumal_3736
RUM: CK1_12690 CK1_12700
ROB: CK5_28700
BYL: A4V09_05450 A4V09_05810
BHAN: CGC63_06525(cooS) CGC63_07980(cooS)
BLAU: DQQ01_10205(cooS)
BPRO: PMF13cell1_00639(cooS1_1) PMF13cell1_04203(cooS) PMF13cell1_04285(cooS1_2)
LACY: A4V08_01520
CSH: Closa_0921
CBOL: CGC65_03955(cooS) CGC65_24000(cooS)
HSD: SD1D_0237
EHL: EHLA_2243
CDF: CD630_01740(cooS) CD630_07160(cooS)
PDC: CDIF630_00296 CDIF630_00832(cooS)
CDC: CD196_0188 CD196_0661(cooS)
CDL: CDR20291_0175 CDR20291_0643(cooS)
PDF: CD630DERM_01740(cooS) CD630DERM_07160(cooS1)
CST: CLOST_1160
PSOR: RSJ16_15770
DSY: DSY1653 DSY2630 DSY4173 DSY4442
DHD: Dhaf_0882 Dhaf_1166 Dhaf_2798 Dhaf_3792
DDH: Desde_1134 Desde_2256 Desde_3264
DDL: Desdi_0655 Desdi_0934 Desdi_1922
DMT: DESME_03525 DESME_07325
DRM: Dred_0652
DCA: Desca_0349 Desca_1148 Desca_1990
DRU: Desru_0859 Desru_3320
DFG: B0537_03940
DAE: Dtox_1270 Dtox_2327 Dtox_2933 Dtox_3780
DKU: Desku_1492 Desku_2150 Desku_2787
DGI: Desgi_0522 Desgi_1185 Desgi_2052 Desgi_2753 Desgi_3080
DAU: Daud_0105 Daud_0870
TJR: TherJR_1157 TherJR_1937 TherJR_2144 TherJR_2959
SGY: Sgly_2814
DOR: Desor_0421 Desor_3274 Desor_4181 Desor_4446
DAI: Desaci_0260 Desaci_0709 Desaci_2975
DMI: Desmer_0456 Desmer_1790 Desmer_2536 Desmer_3209 Desmer_3478
DED: DHBDCA_p230(cooS1)
DEC: DCF50_p290(cooS1)
DRS: DEHRE_00735
ELM: ELI_3603
AWO: Awo_c10740(acsA) Awo_c19050(cooS)
CTHM: CFE_0163 CFE_0173 CFE_0653 CFE_1617 CFE_1666 CFE_1919
AMIJ: EQM06_02755(cooS)
TTE: TTE1708
TKI: TKV_c08080(cooS) TKV_c20100(acsA)
CHY: CHY_0034(cooSV) CHY_0085(cooSII) CHY_0736(cooSIV) CHY_1824(cooSI)
TEP: TepRe1_0548
TAE: TepiRe1_0598(cooS)
MTA: Moth_1203 Moth_1972
ADG: Adeg_0335
TPZ: Tph_c05730(cooS1) Tph_c13580(cooS) Tph_c15180(acsB)
CSC: Csac_0400
CHD: Calhy_0239
CKI: Calkr_0175
CLC: Calla_2155
TOC: Toce_0335 Toce_0761 Toce_0800
TNR: Thena_0036
TACI: TDSAC_0035
NTH: Nther_0860
HALS: D7D81_07270(cooS) D7D81_07945(cooS)
AAR: Acear_0983 Acear_1305
HHL: Halha_1234
CAD: Curi_c06440(cooS)
VPR: Vpar_0209
VAT: B7L28_00930
VRM: 44547418_00230(cooS2)
VDN: NCTC11831_00196(cooS1)
SSG: Selsp_2016
SRI: SELR_14500
PUF: UFO1_0648 UFO1_2774
PFT: JBW_00105 JBW_04289
MANA: MAMMFC1_00477 MAMMFC1_00822(cooS) MAMMFC1_02734(cooS2)
KST: KSMBR1_1326(cdh_acsA) KSMBR1_3765(acsA_2)
TAZ: TREAZ_1535(cooS_2) TREAZ_1650(cooS_1)
TPI: TREPR_3069(cooS)
CPOR: BED41_06285
TOH: BCB71_06635(cooS)
CPC: Cpar_1193
CPH: Cpha266_0149
PROS: CHL67_00350
PMX: PERMA_0106(cooS)
TAM: Theam_1337
DTE: Dester_0417 Dester_0833
DIN: Selin_2012
TID: Thein_1422 Thein_2190
TOP: TOPB45_0398
CTHI: THC_1754
MJA: MJ_0152 MJ_0153 MJ_0728
MFE: Mefer_0203
MVU: Metvu_0628 Metvu_0967 Metvu_1187
MFS: MFS40622_0120 MFS40622_0121 MFS40622_1444
MIF: Metin_1030 Metin_1228
MJH: JH146_0004 JH146_1155
MIG: Metig_0288 Metig_0357 Metig_1381 Metig_1382
MMP: MMP0985(cdhA)
MMQ: MmarC5_0805
MMX: MmarC6_1673
MMZ: MmarC7_0227
MMD: GYY_05750
MAE: Maeo_0475 Maeo_1171 Maeo_1174
MVN: Mevan_0311
MVO: Mvol_0200
MOK: Metok_0743 Metok_0747
MTH: MTH_1708
MMG: MTBMA_c02870(cdhA1) MTBMA_c14200(cdhA2) MTBMA_c14210(cdhA3)
METC: MTCT_1561
MWO: MWSIV6_0249(cdhA1) MWSIV6_0986(cdhA3) MWSIV6_0987(cdhA5)
METE: tca_00999 tca_01655
MEL: Metbo_0462
MEW: MSWAN_1934
METH: MBMB1_1565(cdhA)
MFC: BRM9_0801(cdhA)
MFI: DSM1535_0763(cdhA)
MCUB: MCBB_1821(cdhA)
MSUB: BK009_06810
METN: BK008_02455
METT: CIT01_07270(cdhA)
METO: CIT02_10120(cdhA)
MFV: Mfer_0527
MKA: MK0536 MK0717(cdhA_1) MK0719(cdhA_1)
AFU: AF_1100 AF_1849 AF_2397
AFG: AFULGI_00011970 AFULGI_00021030 AFULGI_00026580
AVE: Arcve_1121
AST: Asulf_01231 Asulf_02029
FPL: Ferp_0731 Ferp_2369 Ferp_2562
GAC: GACE_0127 GACE_0359
GAH: GAH_01139 GAH_01577
MEAR: Mpt1_c02980
TON: TON_1018
TGA: TGAM_0824(cooS)
TBA: TERMP_01153
THA: TAM4_1067 TAM4_582
THS: TES1_1211
TGY: X802_05885
TBS: A3L01_08235
THH: CDI07_07345(cooS)
TSL: A3L11_01585
TPRF: A3L09_01360
TRL: A3L10_07625
MAC: MA_1016(cdhA) MA_1309(cooS) MA_3282(cooS) MA_3860(cdhA) MA_4399(cdhA)
MBA: Mbar_A0204 Mbar_A0434 Mbar_A3525 Mbar_A3717
MBY: MSBRM_0628 MSBRM_1052 MSBRM_2317 MSBRM_2755
MBW: MSBRW_0567 MSBRW_0792 MSBRW_1019 MSBRW_1209
MBAR: MSBR2_0095 MSBR2_1359 MSBR2_1750 MSBR2_2713
MBAK: MSBR3_0095 MSBR3_2715 MSBR3_2955
MMA: MM_0121 MM_0684 MM_2089 MM_2301
MMAZ: MmTuc01_0129 MmTuc01_0700 MmTuc01_2347
MMJ: MSMAS_0630 MSMAS_1212 MSMAS_2399 MSMAS_2596
MMAC: MSMAC_0632 MSMAC_1824 MSMAC_2048 MSMAC_2550
MVC: MSVAZ_0995 MSVAZ_2289 MSVAZ_2495 MSVAZ_3017
MEK: MSKOL_0967 MSKOL_2294 MSKOL_2507 MSKOL_3020
MLS: MSLAZ_0649 MSLAZ_0996 MSLAZ_1465
METM: MSMTP_0687 MSMTP_0695 MSMTP_0809 MSMTP_1179 MSMTP_1309
MEF: MSWH1_0796 MSWH1_2253
MEQ: MSWHS_0848 MSWHS_2820 MSWHS_3011
MSJ: MSSAC_0985 MSSAC_3454 MSSAC_3597 MSSAC_4086
MSZ: MSSIH_0886 MSSIH_2982 MSSIH_3137 MSSIH_3621
MSW: MSSIT_0920 MSSIT_3039 MSSIT_3040 MSSIT_3208 MSSIT_3674
MTHE: MSTHC_0600 MSTHC_0940
MTHR: MSTHT_0128 MSTHT_2340
MHOR: MSHOH_0739 MSHOH_2496 MSHOH_3023 MSHOH_3042 MSHOH_3260
MFZ: AOB57_003735(cdhA)
MBU: Mbur_0858
MMET: MCMEM_0990
MMH: Mmah_1166
MHAZ: BHR79_07705
MEV: Metev_0426
MZH: Mzhil_1137
MPY: Mpsy_0694 Mpsy_2895
MHZ: Metho_0975 Metho_1412
MTP: Mthe_0292 Mthe_1216 Mthe_1341
MCJ: MCON_1332(cdhA) MCON_2865(cooS)
MHI: Mhar_0789 Mhar_1630 Mhar_2328
MHU: Mhun_0690 Mhun_1272
MBG: BN140_2260(cooS)
MEMA: MMAB1_2986(cooS)
MPI: Mpet_0907
MBN: Mboo_0884 Mboo_1373
MFO: Metfor_1721
MPL: Mpal_0842
RCI: LRC456(cdhA)
TCB: TCARB_0870
KCR: Kcr_0762
BARC: AOA65_0464(cdhA2) AOA65_1716(cdhA)
BARB: AOA66_1428(cdhA2)
DBLINKS ExplorEnz - The Enzyme Database: 1.2.7.4
IUBMB Enzyme Nomenclature: 1.2.7.4
ExPASy - ENZYME nomenclature database: 1.2.7.4
BRENDA, the Enzyme Database: 1.2.7.4
///
ENTRY EC 1.17.1.10 Enzyme
NAME formate dehydrogenase (NADP+);
NADP+-dependent formate dehydrogenase
CLASS Oxidoreductases;
Acting on CH or CH2 groups;
With NAD+ or NADP+ as acceptor
SYSNAME formate:NADP+ oxidoreductase
REACTION formate + NADP+ = CO2 + NADPH [RN:R00134]
ALL_REAC R00134
SUBSTRATE formate [CPD:C00058];
NADP+ [CPD:C00006]
PRODUCT CO2 [CPD:C00011];
NADPH [CPD:C00005]
COMMENT A tungsten-selenium-iron protein characterized from the bacterium Moorella thermoacetica. It is extremely sensitive to oxygen.
HISTORY EC 1.17.1.10 created 1978 as EC 1.2.1.43, transferred 2017 to EC 1.17.1.10
REFERENCE 1 [PMID:4154039]
AUTHORS Andreesen JR, Ljungdahl LG.
TITLE Nicotinamide adenine dinucleotide phosphate-dependent formate dehydrogenase from Clostridium thermoaceticum: purification and properties.
JOURNAL J Bacteriol 120:6-14 (1974)
REFERENCE 2 [PMID:6822536]
AUTHORS Yamamoto I, Saiki T, Liu SM, Ljungdahl LG.
TITLE Purification and properties of NADP-dependent formate dehydrogenase from Clostridium thermoaceticum, a tungsten-selenium-iron protein.
JOURNAL J Biol Chem 258:1826-32 (1983)
PATHWAY ec00680 Methane metabolism
ec00720 Carbon fixation pathways in prokaryotes
ec01100 Metabolic pathways
ec01120 Microbial metabolism in diverse environments
ORTHOLOGY K05299 formate dehydrogenase (NADP+) alpha subunit
K15022 formate dehydrogenase (NADP+) beta subunit
GENES LHK: LHK_02330
SUTT: SUTMEG_16550
BBAY: A4V04_04855
HBL: XJ32_06675
WSU: WS0477(FDHB)
TDN: Suden_1824
SUA: Saut_1830
SKU: Sulku_0269
SULR: B649_01165
HYO: NNO_1954
NSA: Nitsa_0162
NIS: NIS_0293
SUN: SUN_2227
SLH: YH65_00465
GSU: GSU0509(sfrA) GSU0510(sfrB)
GSK: KN400_0498(sfrA) KN400_0499(sfrB)
GME: Gmet_3022(sfrA) Gmet_3023(sfrB)
GUR: Gura_3639 Gura_3640
GLO: Glov_0660 Glov_0661
GBM: Gbem_0659(sfrB) Gbem_0660(sfrA)
GEO: Geob_1607(sfrB) Geob_1608(sfrA)
GEM: GM21_0672 GM21_0673
GEB: GM18_3695 GM18_3696
GPI: GPICK_13835 GPICK_13840
GSB: GSUB_01595 GSUB_01600
PCA: Pcar_2503(sfrB)
DES: DSOUD_3426 DSOUD_3427
DEU: DBW_0666 DBW_0667
DVU: DVU1772
DVL: Dvul_1383
DVG: Deval_1526
DDS: Ddes_1543
DEF: CNY67_05260
PPRF: DPRO_0998
DBA: Dbac_0167
DPS: DP0682
DAL: Dalk_2557 Dalk_2597
DAT: HRM2_16890(fdhA6) HRM2_26590(gltD1)
DTO: TOL2_C28850(fdhA2)
DAO: Desac_1071 Desac_2111
DTI: Desti_2930 Desti_2931
DBR: Deba_0487 Deba_0488
RPA: RPA0135
RPE: RPE_3861
RPT: Rpal_0138
RPX: Rpdx1_0129
BVR: BVIR_2956
BLAG: BLTE_01210
RHC: RGUI_3847
DSY: DSY3968(fdhF)
DHD: Dhaf_1398
DDH: Desde_1318
DDL: Desdi_1184
DCA: Desca_2053
DAE: Dtox_3503 Dtox_3507
DGI: Desgi_2136 Desgi_3847
DAU: Daud_0104
TJR: TherJR_0670 TherJR_0942
SGY: Sgly_2685
DOR: Desor_0661 Desor_4477
DAI: Desaci_0777
DMI: Desmer_0214 Desmer_0713
DED: DHBDCA_p1614
DEC: DCF50_p1622
DRS: DEHRE_11885
HMO: HM1_1745(fdhA)
CHY: CHY_0733(fdhA)
MTA: Moth_2314
ADG: Adeg_0156 Adeg_0334
TOC: Toce_0785
NTH: Nther_0100
AAR: Acear_2299
CAD: Curi_c16640(fdhB)
DLY: Dehly_0227
DDF: DEFDS_1613
DAP: Dacet_2494
CNI: Calni_1870
FSI: Flexsi_0433
GTL: EP073_00480
MTH: MTH_1552
MMG: MTBMA_c01380(fdhA1)
METC: MTCT_1417
MEL: Metbo_2515
MTP: Mthe_0915
DBLINKS ExplorEnz - The Enzyme Database: 1.17.1.10
IUBMB Enzyme Nomenclature: 1.17.1.10
ExPASy - ENZYME nomenclature database: 1.17.1.10
BRENDA, the Enzyme Database: 1.17.1.10
CAS: 51377-43-6
///
ENTRY EC 6.3.4.3 Enzyme
NAME formate---tetrahydrofolate ligase;
formyltetrahydrofolate synthetase;
10-formyltetrahydrofolate synthetase;
tetrahydrofolic formylase;
tetrahydrofolate formylase
CLASS Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
SYSNAME formate:tetrahydrofolate ligase (ADP-forming)
REACTION ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate [RN:R00943]
ALL_REAC R00943
SUBSTRATE ATP [CPD:C00002];
formate [CPD:C00058];
tetrahydrofolate [CPD:C00101]
PRODUCT ADP [CPD:C00008];
phosphate [CPD:C00009];
10-formyltetrahydrofolate [CPD:C00234]
COMMENT In eukaryotes occurs as a trifunctional enzyme also having methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) and methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) activity.
HISTORY EC 6.3.4.3 created 1961
REFERENCE 1 [PMID:13789141]
AUTHORS JAENICKE L, BRODE E.
TITLE [Research on monocarbon compounds. I. The tetrahydrofolate formylase from pigeon liver. Purification and mechanism.]
JOURNAL Biochem Z 334:108-32 (1961)
REFERENCE 2
AUTHORS Long, C.W., Levitzki, A., Houston, L.L and Koshland, D.E., Jr.
TITLE Subunit structures and interactions of CTP synthetase.
JOURNAL Fed Proc 28:342 (1969)
REFERENCE 3 [PMID:14489619]
AUTHORS RABINOWITZ JC, PRICER WE Jr.
TITLE Formyltetrahydrofolate synthetase. I. Isolation and crystallization of the enzyme.
JOURNAL J Biol Chem 237:2898-902 (1962)
REFERENCE 4 [PMID:13654413]
AUTHORS WHITELEY HR, OSBORN MJ, HUENNEKENS FM.
TITLE Purification and properties of the formate-activating enzyme from Micrococcus aerogenes.
JOURNAL J Biol Chem 234:1538-43 (1959)
PATHWAY ec00670 One carbon pool by folate
ec00720 Carbon fixation pathways in prokaryotes
ec01100 Metabolic pathways
ec01120 Microbial metabolism in diverse environments
ORTHOLOGY K00288 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase
K01938 formate--tetrahydrofolate ligase
K13402 monofunctional C1-tetrahydrofolate synthase, mitochondrial
GENES HSA: 25902(MTHFD1L) 4522(MTHFD1)
PTR: 452965(MTHFD1) 463073(MTHFD1L)
PPS: 100983723(MTHFD1L) 100986093(MTHFD1)
GGO: 101136018(MTHFD1L) 101145772(MTHFD1)
PON: 100173036(MTHFD1) 100437887(MTHFD1L)
NLE: 100591295 100592446(MTHFD1) 100597135(MTHFD1L)
MCC: 705222(MTHFD1L) 707059(MTHFD1)
MCF: 101925793(MTHFD1L) 102146226(MTHFD1)
CSAB: 103229163(MTHFD1) 103241030(MTHFD1L)
RRO: 104678347(MTHFD1L) 104678419(MTHFD1)
RBB: 108539138(MTHFD1L) 108542410(MTHFD1)
CJC: 100385373(MTHFD1) 100395925(MTHFD1L)
SBQ: 101041831(MTHFD1L) 101050716(MTHFD1)
MMU: 108156(Mthfd1) 270685(Mthfd1l)
RNO: 361472(Mthfd1l) 64300(Mthfd1)
MUN: 110547762(Mthfd1) 110552873(Mthfd1l)
CGE: 100763862(Mthfd1) 100767336(Mthfd1l)
NGI: 103730291 103745750(Mthfd1l) 103749265(Mthfd1)
HGL: 101707403(Mthfd1) 101720005(Mthfd1l)
CCAN: 109691124(Mthfd1) 109694193(Mthfd1l)
OCU: 100343064(MTHFD1L) 100347271(MTHFD1)
TUP: 102473748(MTHFD1) 102484216(MTHFD1L)
CFA: 476245(MTHFD1L) 480352(MTHFD1)
AML: 100467466(MTHFD1) 100477350(MTHFD1L)
UMR: 103666965(MTHFD1L) 103672303(MTHFD1)
ORO: 101377610(MTHFD1L) 101381197(MTHFD1)
FCA: 101082751(MTHFD1L) 101086816(MTHFD1)
PTG: 102969144(MTHFD1L) 102971656(MTHFD1)
AJU: 106971326(MTHFD1) 106976246(MTHFD1L)
BTA: 534296(MTHFD1L) 534382(MTHFD1)
BOM: 102266073(MTHFD1L) 102275233(MTHFD1)
BIU: 109563582(MTHFD1L) 109565242(MTHFD1)
PHD: 102334237(MTHFD1) 102339331
CHX: 102186214(MTHFD1) 102188948(MTHFD1L)
OAS: 101102245(MTHFD1L) 101109020(MTHFD1)
SSC: 100154722(MTHFD1L) 414382(MTHFD1)
CFR: 102504065(MTHFD1) 102504672(MTHFD1L)
CDK: 105086194(MTHFD1) 105100923(MTHFD1L)
BACU: 103016509 103017005(MTHFD1)
LVE: 103076725 103090767(MTHFD1)
OOR: 101275041(MTHFD1) 101280612(MTHFD1L)
DLE: 111166931(MTHFD1L) 111173070(MTHFD1)
ECB: 100062154(MTHFD1) 100063441(MTHFD1L)
EPZ: 103548986(MTHFD1L) 103559580(MTHFD1)
EAI: 106837310(MTHFD1L) 106839163 106840123
MYB: 102241254(MTHFD1) 102260498(MTHFD1L)
MYD: 102757978(MTHFD1) 102765614(MTHFD1L)
MNA: 107535962(MTHFD1L) 107545676(MTHFD1)
HAI: 109380892(MTHFD1L) 109382053(MTHFD1)
RSS: 109440415 109448237(MTHFD1) 109449332(MTHFD1L)
PALE: 102878910(MTHFD1) 102880268(MTHFD1L)
LAV: 100661814(MTHFD1) 100672390(MTHFD1L)
TMU: 101346017 101351465
MDO: 100027684(MTHFD1) 100032106(MTHFD1L)
SHR: 100913689(MTHFD1L) 100917465(MTHFD1)
PCW: 110208546(MTHFD1L) 110220613(MTHFD1)
OAA: 100074148(MTHFD1L)
GGA: 421633(MTHFD1L) 423508(MTHFD1)
MGP: 100542162(MTHFD1L) 100542376(MTHFD1)
CJO: 107311546(MTHFD1L) 107315290(MTHFD1)
APLA: 101793128(MTHFD1L) 101798457(MTHFD1)
ACYG: 106034225(MTHFD1L) 106037251(MTHFD1)
TGU: 100218066(MTHFD1) 100224764(MTHFD1L)
LSR: 110476032(MTHFD1L) 110484120(MTHFD1)
SCAN: 103820617(MTHFD1L) 103826371(MTHFD1)
GFR: 102039432(MTHFD1L) 102040140(MTHFD1)
FAB: 101810287(MTHFD1L) 101820743(MTHFD1)
PHI: 102101641(MTHFD1) 102103116(MTHFD1L)
PMAJ: 107202026(MTHFD1L) 107206040(MTHFD1)
CCAE: 111926699(MTHFD1L) 111945273 111945401
CCW: 104687153(MTHFD1) 104693880(MTHFD1L)
ETL: 114061116(MTHFD1L) 114063210(MTHFD1)
FPG: 101913340(MTHFD1) 101914730(MTHFD1L)
FCH: 102049730(MTHFD1L) 102059574(MTHFD1)
CLV: 102090180(MTHFD1L) 102091689(MTHFD1)
EGZ: 104131673(MTHFD1) 104133557(MTHFD1L)
NNI: 104010143(MTHFD1) 104013796(MTHFD1L)
ACUN: 113478659(MTHFD1L) 113480420(MTHFD1)
AAM: 106483010(MTHFD1) 106496896(MTHFD1L)
ASN: 102377792(MTHFD1) 102380169 102382003
AMJ: 102576903(MTHFD1) 106736958(MTHFD1L)
PSS: 102448225(MTHFD1L) 102452269(MTHFD1)
CMY: 102934023(MTHFD1L) 102943369(MTHFD1)
CPIC: 101936119(MTHFD1L) 101941983(MTHFD1)
ACS: 100551820(mthfd1l) 100553949(mthfd1)
PVT: 110082112(MTHFD1L) 110082847(MTHFD1)
PBI: 103048947 103050569 103051435 103057636(MTHFD1L) 103058437(MTHFD1)
PMUR: 107285163(MTHFD1) 107292712(MTHFD1L)
GJA: 107107643 107119326(MTHFD1) 107123003(MTHFD1L)
XLA: 108716671(mthfd1l.L) 380266(mthfd1.L)
XTR: 100145211(mthfd1l) 493369(mthfd1)
NPR: 108787125(MTHFD1) 108796152(MTHFD1L)
DRE: 100034522(mthfd1l) 260441(mthfd1b)
SRX: 107711640 107711662 107719198 107721348 107721369 107728958 107736723
SANH: 107659212 107665399 107668238 107672350 107675313(mthfd1) 107680103
SGH: 107555742 107556131 107562682 107571064(mthfd1) 107573126 107602204
CCAR: 109061507 109107607 109113007
IPU: 108257577(mthfd1) 108257638(mthfd1l) 108269612(Mthfd1)
PHYP: 113532344(mthfd1l) 113538830(mthfd1) 113547678
AMEX: 103042181(mthfd1) 103042511(mthfd1l) 103044195
EEE: 113570409(mthfd1l) 113570496 113579870
TRU: 101064259(mthfd1l) 101079275 105418662(mthfd1) 105419500
TNG: GSTEN00008408G001 GSTEN00023066G001 GSTEN00032425G001
LCO: 104924805(mthfd1) 104928886(mthfd1l) 104933183
NCC: 104947195(mthfd1) 104962356(mthfd1l)
MZE: 101477222(mthfd1) 101482183(mthfd1l) 101486590
OLA: 101159402 101162177(mthfd1l) 101174548
XMA: 102224500(mthfd1) 102230963(mthfd1l) 111611432
PRET: 103457130 103457517(mthfd1l) 103458564(mthfd1)
NFU: 107377559(mthfd1l) 107377914 107392490(mthfd1)
KMR: 108232073 108240097(mthfd1l) 108251422
CSEM: 103381100 103381395 103390162(mthfd1) 103399305
LCF: 108880921(mthfd1l) 108890040 108892567
SDU: 111225814 111231664 111238474(mthfd1l)
HCQ: 109526130(mthfd1) 109527607 109531725
BPEC: 110153231(mthfd1l) 110155272 110163840
MALB: 109953407(mthfd1l) 109968362 109974459
SASA: 100306829(mthfd1l) 106581504(mthfd1) 106607641
OTW: 112217304 112217716 112217762 112261855(mthfd1)
SALP: 111968792(mthfd1) 111972649(mthfd1l) 111973247
ELS: 105015635(mthfd1) 105017489(mthfd1l) 105021712
SFM: 108919610(mthfd1) 108920486(mthfd1l)
PKI: 111838814(mthfd1) 111839655 111856751(mthfd1l)
LCM: 102347033(MTHFD1) 102353169 102356084(MTHFD1L)
CMK: 103179237(mthfd1l) 103189752(mthfd1)
BFO: BRAFLDRAFT_120483 BRAFLDRAFT_289526
CIN: 100185664
SPU: 589933(MTHFD1)
APLC: 110975175
SKO: 100366866
DME: Dmel_CG4067(pug)
DPO: Dpse_GA13173
DAN: Dana_GF17545
DER: 6551976
DPE: 6594045
DSE: Dsec_GM23891
DSI: Dsimw501_GD18702(Dsim_GD18702)
DWI: 6648231
DYA: Dyak_GE26043
DGR: Dgri_GH14901
DMO: Dmoj_GI23694
DAZ: 108608669
DHE: 111597189
DVI: Dvir_GJ23253
MDE: 101891351
AGA: AgaP_AGAP002830
AAG: 5567414
CQU: CpipJ_CPIJ014099
AME: 550749
BIM: 100741383
BTER: 100644014
SOC: 105195662
MPHA: 105831994
AEC: 105144492
ACEP: 105622571
PBAR: 105431753
HST: 105192491
DQU: 106744693
CFO: 105252037
LHU: 105668747
PGC: 109852088
OBO: 105274937
PCF: 106792378
NVI: 100118909
MDL: 103575930
TCA: 656820 656994
DPA: 109533007 109542585
NVL: 108563026
BMOR: 101743494
DPL: KGM_211321
PMAC: 106721613
PRAP: 110993574
HAW: 110379090
TNL: 113498638
PXY: 105382326 105390540
API: 100167020
DNX: 107167392
AGS: 114123150
CLEC: 106671085
PHU: Phum_PHUM025050 Phum_PHUM456190
ZNE: 110829788
FCD: 110845338
DPX: DAPPUDRAFT_106818 DAPPUDRAFT_198836 DAPPUDRAFT_248714 DAPPUDRAFT_248715 DAPPUDRAFT_326336 DAPPUDRAFT_67147
TUT: 107361733 107362810
DPTE: 113795631
CEL: CELE_K07E3.4(K07E3.4)
NAI: NECAME_01976 NECAME_01978 NECAME_02558
TSP: Tsp_00651
HRO: HELRODRAFT_104956
LGI: LOTGIDRAFT_201055
PCAN: 112570838
CRG: 105345937
MYI: 110450445
OBI: 106867868 106869903
LAK: 106174568
SMM: Smp_147650
SHX: MS3_07173
OVI: T265_00055
EGL: EGR_08456
NVE: NEMVE_v1g158170
EPA: 110244187
ADF: 107335679 107337241
PDAM: 113676803
SPIS: 111342997
HMG: 100203891 100209510 101238037
TAD: TRIADDRAFT_49681
AQU: 100634307
ATH: AT1G50480(THFS)
ALY: ARALYDRAFT_474176(THFS)
CRB: 17898945
CSAT: 104744022 104758357 104759913 104777977
EUS: EUTSA_v10011315mg
BRP: 103868620 103871345
BNA: 106368826 106405654
BOE: 106300060 106343290
THJ: 104806618
CPAP: 110809536
CIT: 102616080
CIC: CICLE_v10014585mg CICLE_v10014598mg
TCC: 18587219
GRA: 105779835
GHI: 107936203 107939256
GAB: 108460472
DZI: 111295025
EGR: 104422245 104422249 104432971
GMX: 100777027 100782213 100806844
PVU: PHAVU_007G006400g
VRA: 106772396
VAR: 108326250
CCAJ: 109815114
MTR: MTR_1g116140 MTR_5g059390
CAM: 101512635
LJA: Lj0g3v0097989.1(Lj0g3v0097989.1) Lj5g3v2292520.1(Lj5g3v2292520.1)
ADU: 107467640
AIP: 107618167
LANG: 109335783 109346515
FVE: 101291704
PPER: 18773159 18774578
PMUM: 103327220 103328222
PAVI: 110762978 110762980 110763288 110763311
MDM: 103430734 103452435
PXB: 103954008 103963993
ZJU: 107415101
CSV: 101216190
CMO: 103492486
MCHA: 111024074
CMAX: 111466569
CMOS: 111436149
CPEP: 111794071
RCU: 8285804
JCU: 105650953
HBR: 110634750
MESC: 110611350
POP: 7455752 7463602
JRE: 109001687
QSU: 112008097 112008405 112031202 112037075
VVI: 100255218
SLY: 101265950
SPEN: 107002786
SOT: 102587729
CANN: 107874073
NTA: 107785718 107808503 107813791 107830687
NSY: 104227962
NTO: 104086347 104092316
NAU: 109209127
INI: 109152405
SIND: 105163527 105180013
OEU: 111369906 111386114
HAN: 110868471 110890891
LSV: 111887867 111899820
CCAV: 112519244 112525604
DCR: 108196215 108196781
BVG: 104889889
SOE: 110779986 110797363
CQI: 110695932 110736129
NNU: 104587442 104597573
PSOM: 113309635 113320451
OSA: 4347204
DOSA: Os09t0446800-01(Os09g0446800)
OBR: 102701856
BDI: 100821958
ATS: 109773868(LOC109773868)
SBI: 8081018
ZMA: 541944
SITA: 101775060