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DESCRIPTION
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Package: ORFik
Type: Package
Title: Open Reading Frames in Genomics
Version: 1.27.1
Encoding: UTF-8
Authors@R: c(
person(given = "Haakon", family = "Tjeldnes", email = "[email protected]", role = c("aut", "cre", "dtc")),
person(given = "Kornel", family = "Labun", email = "[email protected]", role = c("aut", "cph")),
person(given = "Michal", family = "Swirski", email = "[email protected]", role = c("ctb")),
person(given = "Katarzyna", family = "Chyzynska", email = "[email protected]", role = c("ctb", "dtc")),
person(given = "Yamila", family = "Torres Cleuren", email = "[email protected]", role = c("ctb", "ths")),
person(given = "Eivind", family = "Valen", email = "[email protected]", role = c("ths", "fnd")))
Description: R package for analysis of transcript and translation features through manipulation of sequence data
and NGS data like Ribo-Seq, RNA-Seq, TCP-Seq and CAGE. It is generalized in the sense that any transcript region
can be analysed, as the name hints to it was made with investigation of ribosomal patterns over
Open Reading Frames (ORFs) as it's primary use case.
ORFik is extremely fast through use of C++, data.table and GenomicRanges.
Package allows to reassign starts of the transcripts with the use of CAGE-Seq data,
automatic shifting of RiboSeq reads, finding of Open Reading Frames for
whole genomes and much more.
biocViews: ImmunoOncology, Software, Sequencing, RiboSeq, RNASeq, FunctionalGenomics, Coverage, Alignment, DataImport
License: MIT + file LICENSE
LazyData: TRUE
BugReports: https://github.com/Roleren/ORFik/issues
URL: https://github.com/Roleren/ORFik
Depends:
R (>= 4.1.0),
IRanges (>= 2.17.1),
GenomicRanges (>= 1.35.1),
GenomicAlignments (>= 1.19.0)
Imports:
AnnotationDbi (>= 1.45.0),
Biostrings (>= 2.51.1),
biomaRt,
biomartr (>= 1.0.7),
BiocFileCache,
BiocGenerics (>= 0.29.1),
BiocParallel (>= 1.19.0),
BSgenome,
cowplot (>= 1.0.0),
data.table (>= 1.11.8),
DESeq2 (>= 1.24.0),
fst (>= 0.9.2),
GenomeInfoDb (>= 1.15.5),
GenomicFeatures (>= 1.31.10),
ggplot2 (>= 2.2.1),
gridExtra (>= 2.3),
httr (>= 1.3.0),
jsonlite,
methods (>= 3.6.0),
R.utils,
Rcpp (>= 1.0.0),
Rsamtools (>= 1.35.0),
rtracklayer (>= 1.43.0),
stats,
SummarizedExperiment (>= 1.14.0),
S4Vectors (>= 0.21.3),
tools,
utils,
XML,
xml2 (>= 1.2.0),
withr
RoxygenNote: 7.3.1
Suggests:
testthat,
rmarkdown,
knitr,
BiocStyle,
BSgenome.Hsapiens.UCSC.hg19
LinkingTo: Rcpp
VignetteBuilder: knitr