DESCRIPTION

Package: nebula
Type: Package
Title: Negative Binomial Mixed Models Using Large-Sample Approximation for Differential Expression Analysis of ScRNA-Seq Data
Version: 1.4.2
Date: 2023-07-03
Author: Liang He
Maintainer: Liang He <hyx520101@gmail.com>
Description: A fast negative binomial mixed model for conducting association analysis of multi-subject single-cell data. It can be used for identifying marker genes, differential expression and co-expression analyses. The model includes subject-level random effects to account for the hierarchical structure in multi-subject single-cell data. See He et al. (2021) <doi:10.1038/s42003-021-02146-6>.  
License: GPL-3
Encoding: UTF-8
LazyData: true
Imports: Rcpp (>= 1.0.7), nloptr, stats, Matrix, methods, RSpectra, Rfast, trust, doFuture (>= 0.12.2), future (>= 1.32.0), foreach (>= 1.5.2), doRNG (>= 1.8.6)
LinkingTo: Rcpp, RcppEigen
Depends: R (>= 4.1)
RoxygenNote: 7.2.3
Suggests: knitr, utils,
    rmarkdown
VignetteBuilder: knitr