diff --git a/CHANGELOG.md b/CHANGELOG.md
index a4564602..e297911b 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -4,6 +4,9 @@ Full documentation for rocFFT is available at [rocm.docs.amd.com](https://rocm.d
 
 ## rocFFT 1.0.26 (Unreleased)
 
+### Added
+- CMake support for documentation.
+
 ### Changed
 
 - Multi-device FFTs now allow batch greater than 1.
diff --git a/CMakeLists.txt b/CMakeLists.txt
index 639e9414..1a9d06b9 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -47,6 +47,8 @@ endif()
 
 set( ROCFFT_BUILD_SCOPE ON )
 
+include(GNUInstallDirs)
+
 project( rocfft LANGUAGES CXX C )
 
 # This finds the rocm-cmake project, and installs it if not found
@@ -137,6 +139,9 @@ if(BUILD_FILE_REORG_BACKWARD_COMPATIBILITY AND NOT WIN32)
   )
 endif()
 
+# Enable documentation build
+option(BUILD_DOCS "Build documentation" ON)
+
 set( WARNING_FLAGS -Wall -Wno-unused-function -Wimplicit-fallthrough -Wunreachable-code -Wsign-compare )
 if( WERROR )
   set( WARNING_FLAGS ${WARNING_FLAGS} -Werror )
@@ -252,6 +257,14 @@ if( BUILD_CLIENTS_SAMPLES
   add_subdirectory( clients )
 endif( )
 
+# Handle dependencies
+include(Dependencies)
+
+# Build docs
+if(BUILD_DOCS)
+  add_subdirectory(docs)
+endif()
+
 if(WIN32)
   set(CPACK_SOURCE_GENERATOR "ZIP")
   set(CPACK_GENERATOR "ZIP")
diff --git a/README.md b/README.md
index 5e81a5db..34e253ba 100644
--- a/README.md
+++ b/README.md
@@ -86,6 +86,12 @@ pip3 install -r .sphinx/requirements.txt
 python3 -m sphinx -T -E -b html -d _build/doctrees -D language=en . _build/html
 ```
 
+Alternatively, build with CMake:
+
+```bash
+cmake -DBUILD_DOCS=ON ..
+```
+
 ## Examples
 
 A summary of the latest functionality and workflow to compute an FFT with rocFFT is available [on the ROCm documentation portal][3].
diff --git a/cmake/Dependencies.cmake b/cmake/Dependencies.cmake
new file mode 100644
index 00000000..707b89fd
--- /dev/null
+++ b/cmake/Dependencies.cmake
@@ -0,0 +1,101 @@
+# MIT License
+#
+# Copyright (c) 2023 Advanced Micro Devices, Inc. All rights reserved.
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in all
+# copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+# SOFTWARE.
+
+# ###########################
+# ROCm dependencies
+# ###########################
+
+include(FetchContent)
+
+if(BUILD_DOCS)
+  find_package(ROCM 0.11.0 CONFIG QUIET PATHS "${ROCM_PATH}") # First version with Sphinx doc gen improvement
+  if(NOT ROCM_FOUND)
+    message(STATUS "ROCm CMake not found. Fetching...")
+    set(rocm_cmake_tag
+      "c044bb52ba85058d28afe2313be98d9fed02e293" # develop@2023.09.12. (move to 6.0 tag when released)
+      CACHE STRING "rocm-cmake tag to download")
+    FetchContent_Declare(
+      rocm-cmake
+      GIT_REPOSITORY https://github.com/RadeonOpenCompute/rocm-cmake.git
+      GIT_TAG        ${rocm_cmake_tag}
+      SOURCE_SUBDIR "DISABLE ADDING TO BUILD" # We don't really want to consume the build and test targets of ROCm CMake.
+    )
+    FetchContent_MakeAvailable(rocm-cmake)
+    find_package(ROCM CONFIG REQUIRED NO_DEFAULT_PATH PATHS "${rocm-cmake_SOURCE_DIR}")
+  else()
+    find_package(ROCM 0.11.0 CONFIG REQUIRED PATHS "${ROCM_PATH}")
+  endif()
+
+  if(Python_FIND_VIRTUALENV STREQUAL "ONLY" AND NOT DEFINED ENV{VIRTUAL_ENV})
+    if(NOT EXISTS "${CMAKE_CURRENT_BINARY_DIR}/.venv")
+      message(STATUS "Python virtualenv use requested but not found. Fetching...")
+      find_program(BOOTSTRAP_PYTHON_EXE python3 REQUIRED)
+      execute_process(
+        COMMAND "${BOOTSTRAP_PYTHON_EXE}" -m pip install --user virtualenv
+        OUTPUT_QUIET
+        COMMAND_ERROR_IS_FATAL ANY
+      )
+      execute_process(
+        COMMAND "${BOOTSTRAP_PYTHON_EXE}" -m virtualenv "${CMAKE_CURRENT_BINARY_DIR}/.venv"
+        OUTPUT_QUIET
+        COMMAND_ERROR_IS_FATAL ANY
+      )
+    endif()
+    set(ENV{VIRTUAL_ENV} "${CMAKE_CURRENT_BINARY_DIR}/.venv")
+    
+    if(WIN32)
+      set(ENV{PATH} "${CMAKE_CURRENT_BINARY_DIR}/.venv/Scripts;$ENV{PATH}")
+    else()
+      set(ENV{PATH} "${CMAKE_CURRENT_BINARY_DIR}/.venv/bin:$ENV{PATH}")
+    endif()
+    
+    find_package(Python REQUIRED)
+
+    # TODO: shortcircuit if installed
+    execute_process(
+      COMMAND "${Python_EXECUTABLE}" -m pip install pip-tools
+      OUTPUT_QUIET
+      COMMAND_ERROR_IS_FATAL ANY
+    )
+
+    list(APPEND CMAKE_CONFIGURE_DEPENDS "${PROJECT_SOURCE_DIR}/docs/.sphinx/requirements.in")
+    file(MAKE_DIRECTORY "$ENV{VIRTUAL_ENV}/usr/share/${PROJECT_NAME}")
+    if("${PROJECT_SOURCE_DIR}/docs/.sphinx/requirements.in" IS_NEWER_THAN "$ENV{VIRTUAL_ENV}/usr/share/${PROJECT_NAME}/requirements.txt")
+      execute_process(
+        COMMAND "${Python_EXECUTABLE}" -m piptools compile
+          "${PROJECT_SOURCE_DIR}/docs/.sphinx/requirements.in"
+          --output-file
+          "$ENV{VIRTUAL_ENV}/usr/share/${PROJECT_NAME}/requirements.txt"
+        OUTPUT_QUIET
+        ERROR_QUIET
+        COMMAND_ERROR_IS_FATAL ANY
+      )
+      execute_process(
+        COMMAND "${Python_EXECUTABLE}" -m piptools sync
+          "$ENV{VIRTUAL_ENV}/usr/share/${PROJECT_NAME}/requirements.txt"
+        OUTPUT_QUIET
+        ERROR_QUIET
+        COMMAND_ERROR_IS_FATAL ANY
+      )
+    endif()
+  endif()
+endif()
diff --git a/docs/.doxygen/Doxyfile b/docs/.doxygen/Doxyfile
index 8a68a988..4ec5e351 100644
--- a/docs/.doxygen/Doxyfile
+++ b/docs/.doxygen/Doxyfile
@@ -968,7 +968,7 @@ FILTER_SOURCE_PATTERNS =
 # (index.html). This can be useful if you have a project on for instance GitHub
 # and want to reuse the introduction page also for the doxygen output.
 
-USE_MDFILE_AS_MAINPAGE = ../README.md
+USE_MDFILE_AS_MAINPAGE =
 
 #---------------------------------------------------------------------------
 # Configuration options related to source browsing
diff --git a/docs/CMakeLists.txt b/docs/CMakeLists.txt
new file mode 100644
index 00000000..cdc5fb09
--- /dev/null
+++ b/docs/CMakeLists.txt
@@ -0,0 +1,40 @@
+# MIT License
+#
+# Copyright (c) 2023 Advanced Micro Devices, Inc. All rights reserved.
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in all
+# copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+# SOFTWARE.
+
+include(ROCMSphinxDoc)
+
+file(COPY
+  "${CMAKE_CURRENT_SOURCE_DIR}/.doxygen/Doxyfile"
+  DESTINATION "${CMAKE_CURRENT_BINARY_DIR}")
+
+rocm_add_sphinx_doc(
+    "${CMAKE_CURRENT_SOURCE_DIR}"
+  OUTPUT_DIR html
+  BUILDER html
+  USES_DOXYGEN
+  VARS
+    "doxyfile=${CMAKE_CURRENT_BINARY_DIR}/Doxyfile"
+)
+  
+install(
+  DIRECTORY "${CMAKE_CURRENT_BINARY_DIR}/html"
+  DESTINATION "${CMAKE_INSTALL_DOCDIR}")