diff --git a/pwiz/data/common/cv.cpp b/pwiz/data/common/cv.cpp
index 8273ddac14..fdc01c66fd 100644
--- a/pwiz/data/common/cv.cpp
+++ b/pwiz/data/common/cv.cpp
@@ -1162,7 +1162,7 @@ const TermInfo termInfos_[] =
     {MS_retention_time_s__OBSOLETE, "MS:1001114", "retention time(s)", "Retention time of the spectrum from the source file.", true},
     {MS_scan_number_s__OBSOLETE, "MS:1001115", "scan number(s)", "OBSOLETE: use spectrumID attribute of SpectrumIdentificationResult. Take from mzData.", true},
     {MS_single_protein_identification_statistic, "MS:1001116", "single protein identification statistic", "Results specific for one protein as part of a protein ambiguity group (a result not valid for all the other proteins in the protein ambiguity group).", false},
-    {MS_theoretical_mass, "MS:1001117", "theoretical mass", "The theoretical neutral mass of the molecule (e.g. the peptide sequence and its modifications) not including its charge carrier.", false},
+    {MS_theoretical_neutral_mass, "MS:1001117", "theoretical neutral mass", "The theoretical neutral mass of the molecule (e.g. the peptide sequence and its modifications) not including its charge carrier.", false},
     {MS_param__b_ion, "MS:1001118", "param: b ion", "Parameter information, type of product: b ion with charge on the N-terminal side.", false},
     {MS_param__c_ion, "MS:1001119", "param: c ion", "Parameter information, type of product: c ion with charge on the N-terminal side.", false},
     {MS_SEQUEST_FormatAndLinks, "MS:1001120", "SEQUEST:FormatAndLinks", "", false},
@@ -1226,6 +1226,8 @@ const TermInfo termInfos_[] =
     {MS_database_EST, "MS:1001178", "database EST", "Expressed sequence tag nucleotide sequence database.", false},
     {MS_Cleavage_agent_regular_expression, "MS:1001180", "Cleavage agent regular expression", "Regular expressions for cleavage enzymes.", false},
     {MS_search_statistics, "MS:1001184", "search statistics", "The details of the actual run of the search.", false},
+    {MS_Mobilion_MBI_format, "MS:1001185", "Mobilion MBI format", "Mobilion MBI file format.", false},
+    {MS_Mobilion_MBI_nativeID_format, "MS:1001186", "Mobilion MBI nativeID format", "Native format defined by frame=xsd:nonNegativeInteger scan=xsd:nonNegativeInteger.", false},
     {MS_modification_specificity_peptide_N_term, "MS:1001189", "modification specificity peptide N-term", "As parameter for search engine: apply the modification only at the N-terminus of a peptide.", false},
     {MS_modification_specificity_peptide_C_term, "MS:1001190", "modification specificity peptide C-term", "As parameter for search engine: apply the modification only at the C-terminus of a peptide.", false},
     {MS_p_value_OBSOLETE, "MS:1001191", "p-value", "Quality estimation by p-value.", true},
@@ -2357,7 +2359,7 @@ const TermInfo termInfos_[] =
     {MS_site_global_FDR, "MS:1002339", "site:global FDR", "Estimation of global false discovery rate of peptides with a post-translational modification.", false},
     {MS_ProteomeXchange_project_tag, "MS:1002340", "ProteomeXchange project tag", "Tag that can be added to a ProteomeXchange dataset, to enable the grouping of datasets. One tag can be used for indicating that a given dataset is part of a bigger project, like e.g. the Human Proteome Project.", false},
     {MS_second_pass_peptide_identification, "MS:1002341", "second-pass peptide identification", "A putative identified peptide found in a second-pass search of protein sequences selected from a first-pass search.", false},
-    {MS_MZmine, "MS:1002342", "MZmine", "A framework for differential analysis of mass spectrometry data.", false},
+    {MS_mzmine, "MS:1002342", "mzmine", "A framework for differential analysis of mass spectrometry data.", false},
     {MS_ion_stability_type_OBSOLETE, "MS:1002343", "ion stability type", "Stability type of the ion.", true},
     {MS_Maltcms, "MS:1002344", "Maltcms", "Modular Application Toolkit for Chromatography Mass-Spectrometry is an application framework mainly for developers.", false},
     {MS_PSM_level_attribute, "MS:1002345", "PSM-level attribute", "Attribute of a single peptide-spectrum match.", false},
@@ -3417,6 +3419,20 @@ const TermInfo termInfos_[] =
     {MS_Scout_score, "MS:1003408", "Scout score", "Scout identification search engine score", false},
     {MS_Stellar, "MS:1003409", "Stellar", "Thermo Scientific Stellar mass spectrometer contains a quadrupole mass filter, a collision cell, and a quadrupole linear ion trap mass analyzer.", false},
     {MS_electron_beam_energy, "MS:1003410", "electron beam energy", "The kinetic energy of the electron beam used in dissociation methods induced by a free electron beam, such as electron-capture dissociation (ECD), electron-detachment dissociation (EDD), and electron-activated dissociation (EAD).", false},
+    {MS_Orbitrap_IQ_X, "MS:1003411", "Orbitrap IQ-X", "Thermo Scientific Orbitrap IQ-X mass spectrometer with Tribrid architecture consisting of quadrupole mass filter, linear ion trap and Orbitrap mass analyzers.", false},
+    {MS_timsTOF_Ultra_2, "MS:1003412", "timsTOF Ultra 2", "Bruker Daltonics timsTOF Ultra 2.", false},
+    {MS_Kojak, "MS:1003413", "Kojak", "Kojak open-source crosslinked peptide sequence search engine developed at the Institute for Systems Biology.", false},
+    {MS_Kojak_score, "MS:1003414", "Kojak:score", "The Kojak score for an individual peptide sequence, similar to Comet:xcorr.", false},
+    {MS_Kojak_expectation_value, "MS:1003415", "Kojak:expectation value", "The Kojak expectation value for an individual peptide sequence.", false},
+    {MS_Kojak_matched_ions, "MS:1003416", "Kojak:matched ions", "The number of matched ions for an individual peptide sequence in a Kojak result.", false},
+    {MS_Kojak_consecutive_matched_ions, "MS:1003417", "Kojak:consecutive matched ions", "The highest run of consecutive matched ions for an individual peptide sequence in a Kojak result.", false},
+    {MS_Kojak_delta_score, "MS:1003418", "Kojak:delta score", "The difference between the top Kojak score and the next best Kojak score for a PSM.", false},
+    {MS_Kojak_rank, "MS:1003419", "Kojak:rank", "The rank of an individual peptide from the first pass of the Kojak scoring algorithm. Applies only to sequences in a crosslinked result.", false},
+    {MS_Kojak_score_xlink, "MS:1003420", "Kojak:score xlink", "The Kojak score for a crosslinked pair of peptide sequences, similar to Comet:xcorr.", false},
+    {MS_Kojak_expectation_value_xlink, "MS:1003421", "Kojak:expectation value xlink", "The Kojak expectation value for a crosslinked pair of peptide sequences.", false},
+    {MS_Kojak_matched_ions_xlink, "MS:1003422", "Kojak:matched ions xlink", "The number of matched ions for a crosslinked pair of peptide sequences in a Kojak result.", false},
+    {MS_Orbitrap_Exploris_GC_240, "MS:1003423", "Orbitrap Exploris GC 240", "Orbitrap Exploris GC 240 Mass Spectrometer.", false},
+    {MS_selected_fragment_theoretical_m_z_observed_intensity_spectrum, "MS:1003424", "selected fragment theoretical m/z observed intensity spectrum", "Spectrum for which the peaks are limited to a subset of known product ions that are important for subsequent identification, whose m/z values are corrected to theoretical values, and intensity values are experimentally derived.", false},
     {NCIT_Number_of_Occurrences, "NCIT:3150827", "Number of Occurrences", "The number of times something happened.", false},
     {MS_PSI_MS_CV_Quality_Control_Vocabulary, "MS:4000000", "PSI-MS CV Quality Control Vocabulary", "PSI Quality Control controlled vocabulary term.", false},
     {MS_QC_metric, "MS:4000001", "QC metric", "Parent term for QC metrics, each metric MUST have this as an ancestor in its is_a relations.", false},
@@ -3442,6 +3458,13 @@ const TermInfo termInfos_[] =
     {MS_MS2_metric, "MS:4000022", "MS2 metric", "QC metric based on MS2 events.", false},
     {MS_sample_preparation_metric, "MS:4000023", "sample preparation metric", "QC metric related to the sample preparation.", false},
     {MS_environment_metric, "MS:4000024", "environment metric", "QC metric related to measurements of the ambient environment, such as the laboratory.", false},
+    {MS_precursor_ion_current_chromatogram, "MS:4000025", "precursor ion current chromatogram", "Representation of the ion current assigned to detected precursors in the series of all MS1 spectra versus time.", false},
+    {MS_fragment_ppm_deviation_median, "MS:4000026", "fragment ppm deviation median", "The median of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied.", false},
+    {MS_fragment_ppm_deviation_mean, "MS:4000027", "fragment ppm deviation mean", "The mean of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied", false},
+    {MS_fragment_ppm_deviation_sigma, "MS:4000028", "fragment ppm deviation sigma", "The standard deviation of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied", false},
+    {MS_area_under_TIC_in_MS1, "MS:4000029", "area under TIC in MS1", "The area under the total ion current chromatogram (MS:1000235) of all MS1 spectra.", false},
+    {MS_area_under_TIC_in_MS2, "MS:4000030", "area under TIC in MS2", "The area under the total ion current chromatogram (MS:1000235) of all MS2 spectra.", false},
+    {MS_peak_area_of_MS1_vs_MS2_signal_ratio, "MS:4000031", "peak area of MS1 vs MS2 signal ratio", "The ratio of the area under TIC of MS1 (MS:4000029) divided by the area under the TIC of MS2 (MS:4000030).", false},
     {MS_XIC50_fraction, "MS:4000050", "XIC50 fraction", "The number of XIC that account for the top half of all XIC-FWHM divided by the number of all XIC.", false},
     {MS_XIC_FWHM_quantiles, "MS:4000051", "XIC-FWHM quantiles", "The first to n-th quantile of peak widths for XICs. A metric's value triplet represents the related QuaMeter metrics of XIC-FWHM-Q1,Q2,Q3.", false},
     {MS_XIC_Height_quartile_ratios, "MS:4000052", "XIC-Height quartile ratios", "The log ratio of successive XIC height quartiles. The metric's value triplet represents the log ratios of XIC-height-Q2 to XIC-height-Q1, XIC-height-Q3 to XIC-height-Q2, XIC-height max to XIC-height-Q3.", false},
@@ -5083,9 +5106,9 @@ const TermInfo termInfos_[] =
     {UNIMOD_Xlink_DSPP_331_, "UNIMOD:2060", "Xlink:DSPP[331]", "Tris-quenched monolink of DSPP/TBDSPP crosslinker.", false},
     {UNIMOD_Xlink_DSPP_226_, "UNIMOD:2061", "Xlink:DSPP[226]", "Ammonia-quenched monolink of DSPP/TBDSPP crosslinker.", false},
     {UNIMOD_DBIA, "UNIMOD:2062", "DBIA", "Desthiobiotinylation of cysteine with DBIA probe.", false},
-    {UNIMOD_Mono_N___propargyl_L_Gln_desthiobiotin, "UNIMOD:2067", "Mono_Nγ-propargyl-L-Gln_desthiobiotin", "Monomodification of Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide.", false},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "UNIMOD:2068", "Di_L-Glu_Nγ-propargyl-L-Gln_desthiobiotin", "Dimodification of L-Glu and Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide.", false},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "UNIMOD:2069", "Di_L-Gln_Nγ-propargyl-L-Gln_desthiobiotin", "Dimodification of L-Gln and Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide.", false},
+    {UNIMOD_Mono_Ngamma_propargyl_L_Gln_desthiobiotin, "UNIMOD:2067", "Mono_Ngamma-propargyl-L-Gln_desthiobiotin", "Monomodification of Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide.", false},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "UNIMOD:2068", "Di_L-Glu_Ngamma-propargyl-L-Gln_desthiobiotin", "Dimodification of L-Glu and Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide.", false},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "UNIMOD:2069", "Di_L-Gln_Ngamma-propargyl-L-Gln_desthiobiotin", "Dimodification of L-Gln and Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide.", false},
     {UNIMOD_L_Gln, "UNIMOD:2070", "L-Gln", "Monomodification with glutamine.", false},
     {UNIMOD_Glyceroyl, "UNIMOD:2072", "Glyceroyl", "Glyceroylation.", false},
     {UNIMOD_N6pAMP, "UNIMOD:2073", "N6pAMP", "Plain N6-Propargyl-AMP modified proteins without any clicked enrichment tag.", false},
@@ -5099,6 +5122,25 @@ const TermInfo termInfos_[] =
     {UNIMOD_DVFQQQTGG, "UNIMOD:2085", "DVFQQQTGG", "SUMOylation by Endogenous SUMO2/3 following Lys C and Asp-N serial digestion.", false},
     {UNIMOD_iST_NHS_specific_cysteine_modification, "UNIMOD:2086", "iST-NHS specific cysteine modification", "Preomics iST-NHS Kit specific cysteine modification.", false},
     {UNIMOD_Label_13C_2_15N_1_, "UNIMOD:2088", "Label:13C(2)15N(1)", "13C(2) 15N(1) Silac label.", false},
+    {UNIMOD_DPIA, "UNIMOD:2106", "DPIA", "Desthiobiotinylation of cysteine with DPIA (Desthiobiotin polyethyleneoxide iodoacetamide) probe.", false},
+    {UNIMOD_Acetoacetyl, "UNIMOD:2107", "Acetoacetyl", "Acetoacetylation.", false},
+    {UNIMOD_Isovaleryl, "UNIMOD:2108", "Isovaleryl", "Isovalerylation.", false},
+    {UNIMOD_2_methylbutyryl, "UNIMOD:2109", "2-methylbutyryl", "2-methylbutyrylation.", false},
+    {UNIMOD_Tiglyl, "UNIMOD:2110", "Tiglyl", "Tiglylation.", false},
+    {UNIMOD_3_methylglutaryl, "UNIMOD:2111", "3-methylglutaryl", "3-methylglutarylation.", false},
+    {UNIMOD_3_methylglutaconyl, "UNIMOD:2112", "3-methylglutaconyl", "3-methylglutaconylation.", false},
+    {UNIMOD_3_hydroxy_3_methylglutaryl, "UNIMOD:2113", "3-hydroxy-3-methylglutaryl", "3-hydroxy-3-methylglutarylation.", false},
+    {UNIMOD_Lactylation, "UNIMOD:2114", "Lactylation", "Lactylation(Lac).", false},
+    {UNIMOD_Pyruvoyl, "UNIMOD:2115", "Pyruvoyl", "Pyruvoylation.", false},
+    {UNIMOD_Glyoxylyl, "UNIMOD:2116", "Glyoxylyl", "Glyoxylylation.", false},
+    {UNIMOD_Itaconatyl, "UNIMOD:2117", "Itaconatyl", "Itaconatylation.", false},
+    {UNIMOD_Itaconyl, "UNIMOD:2118", "Itaconyl", "Itaconylation.", false},
+    {UNIMOD_ValGly, "UNIMOD:2119", "ValGly", "UFMylation residue.", false},
+    {UNIMOD_Pentanoyl, "UNIMOD:2120", "Pentanoyl", "Pentanoylation.", false},
+    {UNIMOD_Hexanoyl, "UNIMOD:2121", "Hexanoyl", "Hexanoylation.", false},
+    {UNIMOD_Label_13C_6_15N_2__TMT6plex, "UNIMOD:2122", "Label:13C(6)15N(2)+TMT6plex", "Sixplex Tandem Mass Tag 13C(6) 15N(2) Silac label.", false},
+    {UNIMOD_Label_13C_6_15N_2__TMTpro, "UNIMOD:2123", "Label:13C(6)15N(2)+TMTpro", "TMTpro Tandem Mass Tag 13C(6) 15N(2) Silac label.", false},
+    {UNIMOD_2PCA_triazole_ethanethiol, "UNIMOD:2126", "2PCA-triazole-ethanethiol", "Cleaved 2PCA clicked to biotin-SS-azide.", false},
     {UO_unit, "UO:0000000", "unit", "A unit of measurement is a standardized quantity of a physical quality.", false},
     {UO_length_unit, "UO:0000001", "length unit", "A unit which is a standard measure of the distance between two points.", false},
     {UO_mass_unit, "UO:0000002", "mass unit", "A unit which is a standard measure of the amount of matter/energy of a physical object.", false},
@@ -6512,7 +6554,7 @@ CVIDPair relationsIsA_[] =
     {MS_c_terminal_flanking_residue, MS_peptide_sequence_level_identification_attribute},
     {MS_retention_time_s__OBSOLETE, MS_peptide_sequence_level_identification_attribute},
     {MS_single_protein_identification_statistic, MS_protein_level_identification_attribute},
-    {MS_theoretical_mass, MS_peptide_sequence_level_identification_attribute},
+    {MS_theoretical_neutral_mass, MS_peptide_sequence_level_identification_attribute},
     {MS_param__b_ion, MS_ion_series_considered_in_search},
     {MS_param__c_ion, MS_ion_series_considered_in_search},
     {MS_SEQUEST_FormatAndLinks, MS_SEQUEST_modeCV},
@@ -6580,6 +6622,8 @@ CVIDPair relationsIsA_[] =
     {MS_database_EST, MS_database_type_nucleotide},
     {MS_Cleavage_agent_regular_expression, MS_regular_expression},
     {MS_search_statistics, MS_spectrum_identification_result_details},
+    {MS_Mobilion_MBI_format, MS_mass_spectrometer_file_format},
+    {MS_Mobilion_MBI_nativeID_format, MS_native_spectrum_identifier_format},
     {MS_modification_specificity_peptide_N_term, MS_modification_specificity_rule},
     {MS_modification_specificity_peptide_C_term, MS_modification_specificity_rule},
     {MS_p_value_OBSOLETE, MS_peptide_sequence_level_identification_statistic},
@@ -7646,6 +7690,7 @@ CVIDPair relationsIsA_[] =
     {MS_Comet_spscore, MS_PSM_level_search_engine_specific_statistic},
     {MS_Comet_sprank, MS_PSM_level_search_engine_specific_statistic},
     {MS_Comet_expectation_value, MS_search_engine_specific_score},
+    {MS_Comet_expectation_value, MS_PSM_level_search_engine_specific_statistic},
     {MS_Comet_matched_ions, MS_PSM_level_search_engine_specific_statistic},
     {MS_Comet_total_ions, MS_PSM_level_search_engine_specific_statistic},
     {MS_PSM_FDR_threshold, MS_PSM_level_statistical_threshold},
@@ -7731,8 +7776,8 @@ CVIDPair relationsIsA_[] =
     {MS_site_global_FDR, MS_spectrum_identification_result_details},
     {MS_ProteomeXchange_project_tag, MS_external_reference_identifier},
     {MS_second_pass_peptide_identification, MS_peptide_sequence_level_identification_attribute},
-    {MS_MZmine, MS_analysis_software},
-    {MS_MZmine, MS_data_processing_software},
+    {MS_mzmine, MS_analysis_software},
+    {MS_mzmine, MS_data_processing_software},
     {MS_Maltcms, MS_analysis_software},
     {MS_Maltcms, MS_data_processing_software},
     {MS_PSM_level_attribute, MS_single_identification_result_attribute},
@@ -8514,6 +8559,7 @@ CVIDPair relationsIsA_[] =
     {MS_spectrum_origin_type, MS_spectrum_origin_attribute},
     {MS_observed_spectrum, MS_spectrum_origin_type},
     {MS_predicted_spectrum, MS_spectrum_origin_type},
+    {MS_predicted_spectrum, MS_spectrum_aggregation_type},
     {MS_demultiplexed_spectrum, MS_spectrum_origin_type},
     {MS_uninterpreted_spectrum, MS_spectrum},
     {MS_interpreted_spectrum, MS_spectrum},
@@ -8618,7 +8664,7 @@ CVIDPair relationsIsA_[] =
     {MS_library_spectrum_comment, MS_library_spectrum_attribute},
     {MS_proforma_peptidoform_sequence, MS_peptidoform_sequence},
     {MS_numeric_attribute, MS_object_attribute},
-    {MS_combined_dissociation_method, MS_dissociation_method},
+    {MS_combined_dissociation_method, MS_precursor_activation_attribute},
     {MS_electron_transfer_collision_induced_dissociation, MS_combined_dissociation_method},
     {MS_Synapt_XS, MS_Waters_instrument_model},
     {MS_SELECT_SERIES_Cyclic_IMS, MS_Waters_instrument_model},
@@ -8711,6 +8757,7 @@ CVIDPair relationsIsA_[] =
     {MS_Xevo_G2_XS_QTof, MS_Waters_instrument_model},
     {MS_DIA_NN, MS_quantitation_software_name},
     {MS_DIA_NN, MS_analysis_software},
+    {MS_DIA_NN, MS_library_creation_software},
     {MS_pre_decharged_charge_state, MS_peak_attribute},
     {MS_library_spectrum_cross_reference, MS_library_spectrum_attribute},
     {MS_related_spectrum, MS_library_spectrum_cross_reference},
@@ -8879,6 +8926,22 @@ CVIDPair relationsIsA_[] =
     {MS_Scout_score, MS_PSM_level_search_engine_specific_statistic},
     {MS_Stellar, MS_Thermo_Scientific_instrument_model},
     {MS_electron_beam_energy, MS_precursor_activation_attribute},
+    {MS_Orbitrap_IQ_X, MS_Thermo_Scientific_instrument_model},
+    {MS_timsTOF_Ultra_2, MS_Bruker_Daltonics_timsTOF_series},
+    {MS_Kojak, MS_analysis_software},
+    {MS_Kojak_score, MS_PSM_level_search_engine_specific_statistic},
+    {MS_Kojak_expectation_value, MS_search_engine_specific_score},
+    {MS_Kojak_expectation_value, MS_PSM_level_search_engine_specific_statistic},
+    {MS_Kojak_matched_ions, MS_PSM_level_search_engine_specific_statistic},
+    {MS_Kojak_consecutive_matched_ions, MS_PSM_level_search_engine_specific_statistic},
+    {MS_Kojak_delta_score, MS_PSM_level_search_engine_specific_statistic},
+    {MS_Kojak_rank, MS_PSM_level_search_engine_specific_statistic},
+    {MS_Kojak_score_xlink, MS_PSM_level_search_engine_specific_statistic},
+    {MS_Kojak_expectation_value_xlink, MS_search_engine_specific_score},
+    {MS_Kojak_expectation_value_xlink, MS_PSM_level_search_engine_specific_statistic},
+    {MS_Kojak_matched_ions_xlink, MS_PSM_level_search_engine_specific_statistic},
+    {MS_Orbitrap_Exploris_GC_240, MS_Thermo_Scientific_instrument_model},
+    {MS_selected_fragment_theoretical_m_z_observed_intensity_spectrum, MS_spectrum_origin_type},
     {NCIT_Number_of_Occurrences, NCIT_Number},
     {MS_single_value, MS_QC_metric_value_type},
     {MS_n_tuple, MS_QC_metric_value_type},
@@ -8900,6 +8963,15 @@ CVIDPair relationsIsA_[] =
     {MS_MS2_metric, MS_MS_metric},
     {MS_sample_preparation_metric, MS_QC_metric},
     {MS_environment_metric, MS_QC_metric},
+    {MS_precursor_ion_current_chromatogram, MS_ion_current_chromatogram},
+    {MS_precursor_ion_current_chromatogram, MS_n_tuple},
+    {MS_fragment_ppm_deviation_median, MS_single_value},
+    {MS_fragment_ppm_deviation_mean, MS_single_value},
+    {MS_fragment_ppm_deviation_sigma, MS_single_value},
+    {MS_area_under_TIC_in_MS1, MS_single_value},
+    {MS_area_under_TIC_in_MS2, MS_single_value},
+    {MS_peak_area_of_MS1_vs_MS2_signal_ratio, MS_single_value},
+    {MS_peak_area_of_MS1_vs_MS2_signal_ratio, MS_simple_ratio_of_two_values},
     {MS_XIC50_fraction, MS_single_value},
     {MS_XIC_FWHM_quantiles, MS_n_tuple},
     {MS_XIC_Height_quartile_ratios, MS_n_tuple},
@@ -10540,9 +10612,9 @@ CVIDPair relationsIsA_[] =
     {UNIMOD_Xlink_DSPP_331_, UNIMOD_unimod_root_node},
     {UNIMOD_Xlink_DSPP_226_, UNIMOD_unimod_root_node},
     {UNIMOD_DBIA, UNIMOD_unimod_root_node},
-    {UNIMOD_Mono_N___propargyl_L_Gln_desthiobiotin, UNIMOD_unimod_root_node},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, UNIMOD_unimod_root_node},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, UNIMOD_unimod_root_node},
+    {UNIMOD_Mono_Ngamma_propargyl_L_Gln_desthiobiotin, UNIMOD_unimod_root_node},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, UNIMOD_unimod_root_node},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, UNIMOD_unimod_root_node},
     {UNIMOD_L_Gln, UNIMOD_unimod_root_node},
     {UNIMOD_Glyceroyl, UNIMOD_unimod_root_node},
     {UNIMOD_N6pAMP, UNIMOD_unimod_root_node},
@@ -10556,6 +10628,25 @@ CVIDPair relationsIsA_[] =
     {UNIMOD_DVFQQQTGG, UNIMOD_unimod_root_node},
     {UNIMOD_iST_NHS_specific_cysteine_modification, UNIMOD_unimod_root_node},
     {UNIMOD_Label_13C_2_15N_1_, UNIMOD_unimod_root_node},
+    {UNIMOD_DPIA, UNIMOD_unimod_root_node},
+    {UNIMOD_Acetoacetyl, UNIMOD_unimod_root_node},
+    {UNIMOD_Isovaleryl, UNIMOD_unimod_root_node},
+    {UNIMOD_2_methylbutyryl, UNIMOD_unimod_root_node},
+    {UNIMOD_Tiglyl, UNIMOD_unimod_root_node},
+    {UNIMOD_3_methylglutaryl, UNIMOD_unimod_root_node},
+    {UNIMOD_3_methylglutaconyl, UNIMOD_unimod_root_node},
+    {UNIMOD_3_hydroxy_3_methylglutaryl, UNIMOD_unimod_root_node},
+    {UNIMOD_Lactylation, UNIMOD_unimod_root_node},
+    {UNIMOD_Pyruvoyl, UNIMOD_unimod_root_node},
+    {UNIMOD_Glyoxylyl, UNIMOD_unimod_root_node},
+    {UNIMOD_Itaconatyl, UNIMOD_unimod_root_node},
+    {UNIMOD_Itaconyl, UNIMOD_unimod_root_node},
+    {UNIMOD_ValGly, UNIMOD_unimod_root_node},
+    {UNIMOD_Pentanoyl, UNIMOD_unimod_root_node},
+    {UNIMOD_Hexanoyl, UNIMOD_unimod_root_node},
+    {UNIMOD_Label_13C_6_15N_2__TMT6plex, UNIMOD_unimod_root_node},
+    {UNIMOD_Label_13C_6_15N_2__TMTpro, UNIMOD_unimod_root_node},
+    {UNIMOD_2PCA_triazole_ethanethiol, UNIMOD_unimod_root_node},
     {UO_length_unit, UO_unit},
     {UO_mass_unit, UO_unit},
     {UO_time_unit, UO_unit},
@@ -11291,7 +11382,7 @@ OtherRelationPair relationsOther_[] =
     {MS_release_date, "has_structured_representation_in_format", MS_mzIdentML_format},
     {MS_retention_time_s__OBSOLETE, "has_units", UO_second},
     {MS_retention_time_s__OBSOLETE, "has_units", UO_minute},
-    {MS_theoretical_mass, "has_units", UO_dalton},
+    {MS_theoretical_neutral_mass, "has_units", UO_dalton},
     {MS_SEQUEST_xcorr, "has_order", MS_higher_score_better},
     {MS_DB_MW_filter_maximum, "has_units", UO_dalton},
     {MS_DB_MW_filter_maximum, "has_units", UO_kilodalton},
@@ -11436,6 +11527,7 @@ OtherRelationPair relationsOther_[] =
     {MS_protein_group_level_probability, "has_domain", MS_value_between_0_and_1_inclusive},
     {MS_PIA_protein_score, "has_order", MS_higher_score_better},
     {MS_count_of_identified_proteins, "has_metric_category", MS_ID_based_metric},
+    {MS_count_of_identified_proteins, "has_units", UO_count_unit},
     {MS_protein_group_level_global_FNR, "has_domain", MS_value_between_0_and_1_inclusive},
     {MS_peptide_sequence_level_global_FNR, "has_domain", MS_value_between_0_and_1_inclusive},
     {MS_PSM_level_global_FNR, "has_domain", MS_value_between_0_and_1_inclusive},
@@ -11545,7 +11637,9 @@ OtherRelationPair relationsOther_[] =
     {MS_average_m_z_deviation, "has_units", MS_m_z},
     {MS_average_m_z_deviation, "has_units", UO_parts_per_million},
     {MS_count_of_identified_peptidoforms, "has_metric_category", MS_ID_based_metric},
+    {MS_count_of_identified_peptidoforms, "has_units", UO_count_unit},
     {MS_count_of_identified_spectra, "has_metric_category", MS_ID_based_metric},
+    {MS_count_of_identified_spectra, "has_units", UO_count_unit},
     {MS_related_spectrum_keys, "has_value_type", MS_list_of_integers},
     {MS_similar_spectrum_keys, "has_value_type", MS_list_of_integers},
     {MS_spectrum_cluster_member_spectrum_keys, "has_value_type", MS_list_of_integers},
@@ -11569,16 +11663,52 @@ OtherRelationPair relationsOther_[] =
     {MS_SelexION_separation_voltage, "has_units", UO_volt},
     {MS_Scout_score, "has_order", MS_Scout},
     {MS_electron_beam_energy, "has_units", UO_electronvolt},
+    {MS_Kojak_score, "has_order", MS_higher_score_better},
+    {MS_Kojak_expectation_value, "has_order", MS_lower_score_better},
+    {MS_Kojak_matched_ions, "has_order", MS_higher_score_better},
+    {MS_Kojak_consecutive_matched_ions, "has_order", MS_higher_score_better},
+    {MS_Kojak_delta_score, "has_order", MS_higher_score_better},
+    {MS_Kojak_rank, "has_order", MS_lower_score_better},
+    {MS_Kojak_score_xlink, "has_order", MS_higher_score_better},
+    {MS_Kojak_expectation_value_xlink, "has_order", MS_lower_score_better},
+    {MS_Kojak_matched_ions_xlink, "has_order", MS_higher_score_better},
+    {MS_precursor_ion_current_chromatogram, "has_metric_category", MS_ID_free_metric},
+    {MS_precursor_ion_current_chromatogram, "has_metric_category", MS_single_run_based_metric},
+    {MS_precursor_ion_current_chromatogram, "has_metric_category", MS_chromatogram_metric},
+    {MS_precursor_ion_current_chromatogram, "has_metric_category", MS_XIC_metric},
+    {MS_precursor_ion_current_chromatogram, "has_metric_category", MS_MS1_metric},
+    {MS_fragment_ppm_deviation_median, "has_metric_category", MS_ID_based_metric},
+    {MS_fragment_ppm_deviation_median, "has_metric_category", MS_MS2_metric},
+    {MS_fragment_ppm_deviation_median, "has_units", UO_parts_per_million},
+    {MS_fragment_ppm_deviation_median, "has_value_concept", MS_accuracy},
+    {MS_fragment_ppm_deviation_mean, "has_metric_category", MS_ID_based_metric},
+    {MS_fragment_ppm_deviation_mean, "has_metric_category", MS_MS2_metric},
+    {MS_fragment_ppm_deviation_mean, "has_units", UO_parts_per_million},
+    {MS_fragment_ppm_deviation_mean, "has_value_concept", MS_accuracy},
+    {MS_fragment_ppm_deviation_sigma, "has_metric_category", MS_ID_based_metric},
+    {MS_fragment_ppm_deviation_sigma, "has_metric_category", MS_MS2_metric},
+    {MS_fragment_ppm_deviation_sigma, "has_units", UO_parts_per_million},
+    {MS_fragment_ppm_deviation_sigma, "has_value_concept", MS_precision},
+    {MS_area_under_TIC_in_MS1, "has_metric_category", MS_ID_free_metric},
+    {MS_area_under_TIC_in_MS1, "has_metric_category", MS_chromatogram_metric},
+    {MS_area_under_TIC_in_MS1, "has_metric_category", MS_MS1_metric},
+    {MS_area_under_TIC_in_MS2, "has_metric_category", MS_ID_free_metric},
+    {MS_area_under_TIC_in_MS2, "has_metric_category", MS_chromatogram_metric},
+    {MS_area_under_TIC_in_MS2, "has_metric_category", MS_MS2_metric},
+    {MS_peak_area_of_MS1_vs_MS2_signal_ratio, "has_metric_category", MS_ID_free_metric},
+    {MS_peak_area_of_MS1_vs_MS2_signal_ratio, "has_metric_category", MS_chromatogram_metric},
     {MS_XIC50_fraction, "has_metric_category", MS_ID_free_metric},
     {MS_XIC50_fraction, "has_metric_category", MS_single_run_based_metric},
-    {MS_XIC50_fraction, "has_value_concept", UO_fraction},
+    {MS_XIC50_fraction, "has_units", UO_fraction},
     {MS_XIC_FWHM_quantiles, "has_metric_category", MS_ID_free_metric},
     {MS_XIC_FWHM_quantiles, "has_metric_category", MS_single_run_based_metric},
     {MS_XIC_FWHM_quantiles, "has_metric_category", MS_XIC_metric},
+    {MS_XIC_FWHM_quantiles, "has_units", UO_second},
     {MS_XIC_FWHM_quantiles, "has_value_concept", MS_full_width_at_half_maximum},
     {MS_XIC_Height_quartile_ratios, "has_metric_category", MS_ID_free_metric},
     {MS_XIC_Height_quartile_ratios, "has_metric_category", MS_single_run_based_metric},
     {MS_XIC_Height_quartile_ratios, "has_metric_category", MS_XIC_metric},
+    {MS_XIC_Height_quartile_ratios, "has_units", UO_fraction},
     {MS_chromatography_duration, "has_metric_category", MS_ID_free_metric},
     {MS_chromatography_duration, "has_metric_category", MS_single_run_based_metric},
     {MS_chromatography_duration, "has_metric_category", MS_retention_time_metric},
@@ -11618,6 +11748,7 @@ OtherRelationPair relationsOther_[] =
     {MS_MS1_density_quantiles, "has_metric_category", MS_ID_free_metric},
     {MS_MS1_density_quantiles, "has_metric_category", MS_single_run_based_metric},
     {MS_MS1_density_quantiles, "has_metric_category", MS_MS1_metric},
+    {MS_MS1_density_quantiles, "has_units", UO_count_unit},
     {MS_MS1_density_quantiles, "has_value_concept", NCIT_Density},
     {MS_MS2_density_quantiles, "has_metric_category", MS_ID_free_metric},
     {MS_MS2_density_quantiles, "has_metric_category", MS_single_run_based_metric},
@@ -11651,7 +11782,7 @@ OtherRelationPair relationsOther_[] =
     {MS_MS_run_duration, "has_value_concept", NCIT_Duration},
     {MS_spectra_half_TIC, "has_column", UO_fraction},
     {MS_spectra_half_TIC, "has_metric_category", MS_ID_free_metric},
-    {MS_spectra_half_TIC, "has_metric_category", MS_MS2_metric},
+    {MS_spectra_half_TIC, "has_metric_category", MS_MS_metric},
     {MS_spectra_half_TIC, "has_metric_category", MS_single_run_based_metric},
     {MS_spectra_half_TIC, "has_optional_column", MS_universal_spectrum_identifier},
     {MS_spectra_half_TIC, "has_optional_column", MS_native_spectrum_identifier_format},
@@ -11962,6 +12093,7 @@ OtherRelationPair relationsOther_[] =
     {MS_contaminant_protein_abundance_fraction, "has_domain", MS_value_between_0_and_1_inclusive},
     {MS_contaminant_protein_abundance_fraction, "has_metric_category", MS_ID_based_metric},
     {MS_contaminant_protein_abundance_fraction, "has_order", MS_lower_score_better},
+    {MS_contaminant_protein_abundance_fraction, "has_units", UO_fraction},
     {MS_precursor_ppm_deviation_mean, "has_metric_category", MS_ID_based_metric},
     {MS_precursor_ppm_deviation_mean, "has_metric_category", MS_MS1_metric},
     {MS_precursor_ppm_deviation_mean, "has_units", UO_parts_per_million},
@@ -12146,6 +12278,7 @@ CVIDStringPair relationsExactSynonym_[] =
     {MS_predicted_isoelectric_point, "predicted pI"},
     {MS_unlabeled_peptidoform, "light labeled peptide"},
     {MS_transition, "reaction"},
+    {MS_theoretical_neutral_mass, "theoretical mass"},
     {MS_product_ion_m_z, "fragment ion m/z"},
     {MS_product_ion_intensity, "fragment ion intensity"},
     {MS_Arg_C, "Trypsin/R"},
@@ -12175,6 +12308,7 @@ CVIDStringPair relationsExactSynonym_[] =
     {MS_MS_GF_, "MS-GFDB"},
     {MS_Trans_Proteomic_Pipeline, "TPP"},
     {MS_iProphet, "InterProphet"},
+    {MS_mzmine, "MZmine"},
     {MS_crosslinking_search, "cross-linking search"},
     {MS_crosslinking_attribute, "cross-linking attribute"},
     {MS_crosslink_donor, "cross-link donor"},
@@ -12210,6 +12344,7 @@ CVIDStringPair relationsExactSynonym_[] =
     {MS_ChemClipse, "chemclipse"},
     {MS_OpenChrom, "openchrom"},
     {MS_asymmetric_track_lossless_time_of_flight_analyzer, "Astral"},
+    {MS_precursor_ion_current_chromatogram, "precursor ion chromatogram"},
     {MS_XIC50_fraction, "XIC-WideFrac"},
     {MS_number_of_MS1_spectra, "MS1-Count"},
     {MS_number_of_MS2_spectra, "MS2-Count"},
@@ -13404,6 +13539,10 @@ PropertyValuePair propertyValue_[] =
     {UNIMOD_HNE, "spec_5_hidden", "1"},
     {UNIMOD_HNE, "spec_5_position", "Anywhere"},
     {UNIMOD_HNE, "spec_5_site", "L"},
+    {UNIMOD_HNE, "spec_6_classification", "Post-translational"},
+    {UNIMOD_HNE, "spec_6_hidden", "1"},
+    {UNIMOD_HNE, "spec_6_position", "Anywhere"},
+    {UNIMOD_HNE, "spec_6_site", "R"},
     {UNIMOD_Glucuronyl, "approved", "1"},
     {UNIMOD_Glucuronyl, "delta_composition", "HexA"},
     {UNIMOD_Glucuronyl, "spec_1_classification", "Other glycosylation"},
@@ -25058,8 +25197,8 @@ PropertyValuePair propertyValue_[] =
     {UNIMOD_Cation_Fe_III_, "spec_1_hidden", "1"},
     {UNIMOD_Cation_Fe_III_, "spec_1_position", "Anywhere"},
     {UNIMOD_Cation_Fe_III_, "spec_1_position", "Anywhere"},
-    {UNIMOD_Cation_Fe_III_, "spec_1_site", "D"},
     {UNIMOD_Cation_Fe_III_, "spec_1_site", "E"},
+    {UNIMOD_Cation_Fe_III_, "spec_1_site", "D"},
     {UNIMOD_Cation_Fe_III_, "spec_2_classification", "Artefact"},
     {UNIMOD_Cation_Fe_III_, "spec_2_hidden", "1"},
     {UNIMOD_Cation_Fe_III_, "spec_2_position", "Any C-term"},
@@ -25193,8 +25332,8 @@ PropertyValuePair propertyValue_[] =
     {UNIMOD_Xlink_BuUrBu_111_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_111_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_111_, "spec_3_position", "Anywhere"},
-    {UNIMOD_Xlink_BuUrBu_111_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_111_, "spec_3_site", "T"},
+    {UNIMOD_Xlink_BuUrBu_111_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_111_, "spec_3_site", "Y"},
     {UNIMOD_Xlink_BuUrBu_85_, "approved", "0"},
     {UNIMOD_Xlink_BuUrBu_85_, "delta_composition", "H(7) C(4) N O"},
@@ -25215,8 +25354,8 @@ PropertyValuePair propertyValue_[] =
     {UNIMOD_Xlink_BuUrBu_85_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_85_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_85_, "spec_3_position", "Anywhere"},
-    {UNIMOD_Xlink_BuUrBu_85_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_85_, "spec_3_site", "T"},
+    {UNIMOD_Xlink_BuUrBu_85_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_85_, "spec_3_site", "Y"},
     {UNIMOD_Xlink_BuUrBu_213_, "approved", "0"},
     {UNIMOD_Xlink_BuUrBu_213_, "delta_composition", "H(15) C(9) N(3) O(3)"},
@@ -25237,8 +25376,8 @@ PropertyValuePair propertyValue_[] =
     {UNIMOD_Xlink_BuUrBu_213_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_213_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_213_, "spec_3_position", "Anywhere"},
-    {UNIMOD_Xlink_BuUrBu_213_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_213_, "spec_3_site", "T"},
+    {UNIMOD_Xlink_BuUrBu_213_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_213_, "spec_3_site", "Y"},
     {UNIMOD_Xlink_BuUrBu_214_, "approved", "0"},
     {UNIMOD_Xlink_BuUrBu_214_, "delta_composition", "H(14) C(9) N(2) O(4)"},
@@ -25259,8 +25398,8 @@ PropertyValuePair propertyValue_[] =
     {UNIMOD_Xlink_BuUrBu_214_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_214_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_214_, "spec_3_position", "Anywhere"},
-    {UNIMOD_Xlink_BuUrBu_214_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_214_, "spec_3_site", "T"},
+    {UNIMOD_Xlink_BuUrBu_214_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_214_, "spec_3_site", "Y"},
     {UNIMOD_Xlink_BuUrBu_317_, "approved", "0"},
     {UNIMOD_Xlink_BuUrBu_317_, "delta_composition", "H(23) C(13) N(3) O(6)"},
@@ -25281,8 +25420,8 @@ PropertyValuePair propertyValue_[] =
     {UNIMOD_Xlink_BuUrBu_317_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_317_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_317_, "spec_3_position", "Anywhere"},
-    {UNIMOD_Xlink_BuUrBu_317_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_317_, "spec_3_site", "T"},
+    {UNIMOD_Xlink_BuUrBu_317_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_317_, "spec_3_site", "Y"},
     {UNIMOD_Xlink_DSSO_158_, "approved", "0"},
     {UNIMOD_Xlink_DSSO_158_, "delta_composition", "H(6) C(6) O(3) S"},
@@ -25333,8 +25472,8 @@ PropertyValuePair propertyValue_[] =
     {UNIMOD_Xlink_BuUrBu_196_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_196_, "spec_3_position", "Anywhere"},
     {UNIMOD_Xlink_BuUrBu_196_, "spec_3_position", "Anywhere"},
-    {UNIMOD_Xlink_BuUrBu_196_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_196_, "spec_3_site", "T"},
+    {UNIMOD_Xlink_BuUrBu_196_, "spec_3_site", "S"},
     {UNIMOD_Xlink_BuUrBu_196_, "spec_3_site", "Y"},
     {UNIMOD_Xlink_DTBP_172_, "approved", "0"},
     {UNIMOD_Xlink_DTBP_172_, "delta_composition", "H(8) C(6) N(2) S(2)"},
@@ -26636,32 +26775,32 @@ PropertyValuePair propertyValue_[] =
     {UNIMOD_DBIA, "spec_1_hidden", "1"},
     {UNIMOD_DBIA, "spec_1_position", "Anywhere"},
     {UNIMOD_DBIA, "spec_1_site", "C"},
-    {UNIMOD_Mono_N___propargyl_L_Gln_desthiobiotin, "approved", "0"},
-    {UNIMOD_Mono_N___propargyl_L_Gln_desthiobiotin, "delta_composition", "H(44) C(26) N(8) O(8)"},
-    {UNIMOD_Mono_N___propargyl_L_Gln_desthiobiotin, "spec_1_classification", "Chemical derivative"},
-    {UNIMOD_Mono_N___propargyl_L_Gln_desthiobiotin, "spec_1_hidden", "1"},
-    {UNIMOD_Mono_N___propargyl_L_Gln_desthiobiotin, "spec_1_position", "Anywhere"},
-    {UNIMOD_Mono_N___propargyl_L_Gln_desthiobiotin, "spec_1_site", "C"},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "approved", "0"},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "delta_composition", "H(51) C(31) N(9) O(10)"},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "spec_1_classification", "Chemical derivative"},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "spec_1_hidden", "1"},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "spec_1_position", "Anywhere"},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "spec_1_site", "D"},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "spec_2_classification", "Chemical derivative"},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "spec_2_hidden", "1"},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "spec_2_position", "Anywhere"},
-    {UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin, "spec_2_site", "E"},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "approved", "0"},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "delta_composition", "H(52) C(31) N(10) O(9)"},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "spec_1_classification", "Chemical derivative"},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "spec_1_hidden", "1"},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "spec_1_position", "Anywhere"},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "spec_1_site", "D"},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "spec_2_classification", "Chemical derivative"},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "spec_2_hidden", "1"},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "spec_2_position", "Anywhere"},
-    {UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin, "spec_2_site", "E"},
+    {UNIMOD_Mono_Ngamma_propargyl_L_Gln_desthiobiotin, "approved", "0"},
+    {UNIMOD_Mono_Ngamma_propargyl_L_Gln_desthiobiotin, "delta_composition", "H(44) C(26) N(8) O(8)"},
+    {UNIMOD_Mono_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_classification", "Chemical derivative"},
+    {UNIMOD_Mono_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_hidden", "1"},
+    {UNIMOD_Mono_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_position", "Anywhere"},
+    {UNIMOD_Mono_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_site", "C"},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "approved", "0"},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "delta_composition", "H(51) C(31) N(9) O(10)"},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_classification", "Chemical derivative"},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_hidden", "1"},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_position", "Anywhere"},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_site", "D"},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_2_classification", "Chemical derivative"},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_2_hidden", "1"},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_2_position", "Anywhere"},
+    {UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_2_site", "E"},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "approved", "0"},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "delta_composition", "H(52) C(31) N(10) O(9)"},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_classification", "Chemical derivative"},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_hidden", "1"},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_position", "Anywhere"},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_1_site", "D"},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_2_classification", "Chemical derivative"},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_2_hidden", "1"},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_2_position", "Anywhere"},
+    {UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin, "spec_2_site", "E"},
     {UNIMOD_L_Gln, "approved", "0"},
     {UNIMOD_L_Gln, "delta_composition", "H(8) C(5) N(2) O(2)"},
     {UNIMOD_L_Gln, "spec_1_classification", "Post-translational"},
@@ -26768,6 +26907,120 @@ PropertyValuePair propertyValue_[] =
     {UNIMOD_Label_13C_2_15N_1_, "spec_1_hidden", "1"},
     {UNIMOD_Label_13C_2_15N_1_, "spec_1_position", "Anywhere"},
     {UNIMOD_Label_13C_2_15N_1_, "spec_1_site", "G"},
+    {UNIMOD_DPIA, "approved", "0"},
+    {UNIMOD_DPIA, "delta_composition", "H(37) C(21) N(5) O(6)"},
+    {UNIMOD_DPIA, "spec_1_classification", "Chemical derivative"},
+    {UNIMOD_DPIA, "spec_1_hidden", "1"},
+    {UNIMOD_DPIA, "spec_1_position", "Anywhere"},
+    {UNIMOD_DPIA, "spec_1_site", "C"},
+    {UNIMOD_Acetoacetyl, "approved", "0"},
+    {UNIMOD_Acetoacetyl, "delta_composition", "H(4) C(4) O(2)"},
+    {UNIMOD_Acetoacetyl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_Acetoacetyl, "spec_1_hidden", "1"},
+    {UNIMOD_Acetoacetyl, "spec_1_position", "Anywhere"},
+    {UNIMOD_Acetoacetyl, "spec_1_site", "K"},
+    {UNIMOD_Isovaleryl, "approved", "0"},
+    {UNIMOD_Isovaleryl, "delta_composition", "H(8) C(5) O"},
+    {UNIMOD_Isovaleryl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_Isovaleryl, "spec_1_hidden", "1"},
+    {UNIMOD_Isovaleryl, "spec_1_position", "Anywhere"},
+    {UNIMOD_Isovaleryl, "spec_1_site", "K"},
+    {UNIMOD_2_methylbutyryl, "approved", "0"},
+    {UNIMOD_2_methylbutyryl, "delta_composition", "H(8) C(5) O"},
+    {UNIMOD_2_methylbutyryl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_2_methylbutyryl, "spec_1_hidden", "1"},
+    {UNIMOD_2_methylbutyryl, "spec_1_position", "Anywhere"},
+    {UNIMOD_2_methylbutyryl, "spec_1_site", "K"},
+    {UNIMOD_Tiglyl, "approved", "0"},
+    {UNIMOD_Tiglyl, "delta_composition", "H(6) C(5) O"},
+    {UNIMOD_Tiglyl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_Tiglyl, "spec_1_hidden", "1"},
+    {UNIMOD_Tiglyl, "spec_1_position", "Anywhere"},
+    {UNIMOD_Tiglyl, "spec_1_site", "K"},
+    {UNIMOD_3_methylglutaryl, "approved", "0"},
+    {UNIMOD_3_methylglutaryl, "delta_composition", "H(8) C(6) O(3)"},
+    {UNIMOD_3_methylglutaryl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_3_methylglutaryl, "spec_1_hidden", "1"},
+    {UNIMOD_3_methylglutaryl, "spec_1_position", "Anywhere"},
+    {UNIMOD_3_methylglutaryl, "spec_1_site", "K"},
+    {UNIMOD_3_methylglutaconyl, "approved", "0"},
+    {UNIMOD_3_methylglutaconyl, "delta_composition", "H(6) C(6) O(3)"},
+    {UNIMOD_3_methylglutaconyl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_3_methylglutaconyl, "spec_1_hidden", "1"},
+    {UNIMOD_3_methylglutaconyl, "spec_1_position", "Anywhere"},
+    {UNIMOD_3_methylglutaconyl, "spec_1_site", "K"},
+    {UNIMOD_3_hydroxy_3_methylglutaryl, "approved", "0"},
+    {UNIMOD_3_hydroxy_3_methylglutaryl, "delta_composition", "H(8) C(6) O(4)"},
+    {UNIMOD_3_hydroxy_3_methylglutaryl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_3_hydroxy_3_methylglutaryl, "spec_1_hidden", "1"},
+    {UNIMOD_3_hydroxy_3_methylglutaryl, "spec_1_position", "Anywhere"},
+    {UNIMOD_3_hydroxy_3_methylglutaryl, "spec_1_site", "K"},
+    {UNIMOD_Lactylation, "approved", "0"},
+    {UNIMOD_Lactylation, "delta_composition", "H(4) C(3) O(2)"},
+    {UNIMOD_Lactylation, "spec_1_classification", "Post-translational"},
+    {UNIMOD_Lactylation, "spec_1_hidden", "1"},
+    {UNIMOD_Lactylation, "spec_1_position", "Anywhere"},
+    {UNIMOD_Lactylation, "spec_1_site", "K"},
+    {UNIMOD_Pyruvoyl, "approved", "0"},
+    {UNIMOD_Pyruvoyl, "delta_composition", "H(2) C(3) O(2)"},
+    {UNIMOD_Pyruvoyl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_Pyruvoyl, "spec_1_hidden", "1"},
+    {UNIMOD_Pyruvoyl, "spec_1_position", "Anywhere"},
+    {UNIMOD_Pyruvoyl, "spec_1_site", "K"},
+    {UNIMOD_Glyoxylyl, "approved", "0"},
+    {UNIMOD_Glyoxylyl, "delta_composition", "C(2) O(2)"},
+    {UNIMOD_Glyoxylyl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_Glyoxylyl, "spec_1_hidden", "1"},
+    {UNIMOD_Glyoxylyl, "spec_1_position", "Anywhere"},
+    {UNIMOD_Glyoxylyl, "spec_1_site", "K"},
+    {UNIMOD_Itaconatyl, "approved", "0"},
+    {UNIMOD_Itaconatyl, "delta_composition", "H(6) C(5) O(4)"},
+    {UNIMOD_Itaconatyl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_Itaconatyl, "spec_1_hidden", "1"},
+    {UNIMOD_Itaconatyl, "spec_1_position", "Anywhere"},
+    {UNIMOD_Itaconatyl, "spec_1_site", "C"},
+    {UNIMOD_Itaconyl, "approved", "0"},
+    {UNIMOD_Itaconyl, "delta_composition", "H(4) C(5) O(3)"},
+    {UNIMOD_Itaconyl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_Itaconyl, "spec_1_hidden", "1"},
+    {UNIMOD_Itaconyl, "spec_1_position", "Anywhere"},
+    {UNIMOD_Itaconyl, "spec_1_site", "K"},
+    {UNIMOD_ValGly, "approved", "0"},
+    {UNIMOD_ValGly, "delta_composition", "H(12) C(7) N(2) O(2)"},
+    {UNIMOD_ValGly, "spec_1_classification", "Post-translational"},
+    {UNIMOD_ValGly, "spec_1_hidden", "1"},
+    {UNIMOD_ValGly, "spec_1_position", "Anywhere"},
+    {UNIMOD_ValGly, "spec_1_site", "K"},
+    {UNIMOD_Pentanoyl, "approved", "0"},
+    {UNIMOD_Pentanoyl, "delta_composition", "H(8) C(5) O"},
+    {UNIMOD_Pentanoyl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_Pentanoyl, "spec_1_hidden", "1"},
+    {UNIMOD_Pentanoyl, "spec_1_position", "Anywhere"},
+    {UNIMOD_Pentanoyl, "spec_1_site", "K"},
+    {UNIMOD_Hexanoyl, "approved", "0"},
+    {UNIMOD_Hexanoyl, "delta_composition", "H(10) C(6) O"},
+    {UNIMOD_Hexanoyl, "spec_1_classification", "Post-translational"},
+    {UNIMOD_Hexanoyl, "spec_1_hidden", "1"},
+    {UNIMOD_Hexanoyl, "spec_1_position", "Anywhere"},
+    {UNIMOD_Hexanoyl, "spec_1_site", "K"},
+    {UNIMOD_Label_13C_6_15N_2__TMT6plex, "approved", "0"},
+    {UNIMOD_Label_13C_6_15N_2__TMT6plex, "delta_composition", "H(20) C(2) 13C(10) N(-1) 15N(3) O(2)"},
+    {UNIMOD_Label_13C_6_15N_2__TMT6plex, "spec_1_classification", "Multiple"},
+    {UNIMOD_Label_13C_6_15N_2__TMT6plex, "spec_1_hidden", "1"},
+    {UNIMOD_Label_13C_6_15N_2__TMT6plex, "spec_1_position", "Anywhere"},
+    {UNIMOD_Label_13C_6_15N_2__TMT6plex, "spec_1_site", "K"},
+    {UNIMOD_Label_13C_6_15N_2__TMTpro, "approved", "0"},
+    {UNIMOD_Label_13C_6_15N_2__TMTpro, "delta_composition", "H(25) C(2) 13C(13) N(-1) 15N(4) O(3)"},
+    {UNIMOD_Label_13C_6_15N_2__TMTpro, "spec_1_classification", "Multiple"},
+    {UNIMOD_Label_13C_6_15N_2__TMTpro, "spec_1_hidden", "1"},
+    {UNIMOD_Label_13C_6_15N_2__TMTpro, "spec_1_position", "Anywhere"},
+    {UNIMOD_Label_13C_6_15N_2__TMTpro, "spec_1_site", "K"},
+    {UNIMOD_2PCA_triazole_ethanethiol, "approved", "0"},
+    {UNIMOD_2PCA_triazole_ethanethiol, "delta_composition", "H(8) C(10) N(4) S"},
+    {UNIMOD_2PCA_triazole_ethanethiol, "spec_1_classification", "Other"},
+    {UNIMOD_2PCA_triazole_ethanethiol, "spec_1_hidden", "1"},
+    {UNIMOD_2PCA_triazole_ethanethiol, "spec_1_position", "Any N-term"},
+    {UNIMOD_2PCA_triazole_ethanethiol, "spec_1_site", "N-term"},
 }; // propertyValue_
 
 
@@ -26819,16 +27072,16 @@ class CVTermData : public boost::singleton<CVTermData>
         cvMap_["PEFF"].URI = cvMap_["MS"].URI;
 
         cvMap_["MS"].id = "MS";
-        cvMap_["MS"].version = "4.1.163";
+        cvMap_["MS"].version = "4.1.182";
 
         cvMap_["NCIT"].id = "NCIT";
-        cvMap_["NCIT"].version = "4.1.163";
+        cvMap_["NCIT"].version = "4.1.182";
 
         cvMap_["PEFF"].id = "PEFF";
-        cvMap_["PEFF"].version = "4.1.163";
+        cvMap_["PEFF"].version = "4.1.182";
 
         cvMap_["UNIMOD"].id = "UNIMOD";
-        cvMap_["UNIMOD"].version = "2024-02-29";
+        cvMap_["UNIMOD"].version = "2024-08-12";
 
         cvMap_["UO"].id = "UO";
         cvMap_["UO"].version = "09:04:2014";
diff --git a/pwiz/data/common/cv.hpp b/pwiz/data/common/cv.hpp
index 284a328c9a..c41a930b87 100644
--- a/pwiz/data/common/cv.hpp
+++ b/pwiz/data/common/cv.hpp
@@ -41,8 +41,8 @@
 // [psi-ms.obo]
 #define _PSI_MS_OBO_
 //   format-version: 1.2
-//   data-version: 4.1.163
-//   date: 19:07:2024 07:15
+//   data-version: 4.1.182
+//   date: 11:10:2024 07:15
 //   saved-by: Joshua Klein
 //   auto-generated-by: OBO-Edit 2.3.1
 //   default-namespace: MS
@@ -62,7 +62,7 @@
 //   remark: creator: Gerhard Mayer <mayerg97 <-at-> rub.de>
 //   remark: creator: Joshua Klein <jaklein <-at-> bu.edu>
 //   remark: creator: Chris Bielow <chris.bielow <-at-> fu-berlin.de>
-//   remark: creator: Wout Bittremieux <wbittremieux <-at-> health.ucsd.edu>
+//   remark: creator: Wout Bittremieux <wout.bittremieux <-at-> uantwerpen.be>
 //   remark: creator: Nils Hoffmann < nils.hoffmann <-at-> cebitec.uni-bielefeld.de>
 //   remark: creator: Julian Uszkoreit <julian.uszkoreit <-at-> ruhr-uni-bochum.de>
 //   remark: creator: Mathias Walzer <walzer <-at-> ebi.ac.uk>
@@ -77,7 +77,7 @@
 // [unimod.obo]
 #define _UNIMOD_OBO_
 //   format-version: 1.4
-//   date: 29:02:2024 10:49
+//   date: 12:08:2024 11:33
 //
 // [unit.obo]
 #define _UNIT_OBO_
@@ -3896,8 +3896,11 @@ enum PWIZ_API_DECL CVID
     /// single protein identification statistic: Results specific for one protein as part of a protein ambiguity group (a result not valid for all the other proteins in the protein ambiguity group).
     MS_single_protein_identification_statistic = 1001116,
 
-    /// theoretical mass: The theoretical neutral mass of the molecule (e.g. the peptide sequence and its modifications) not including its charge carrier.
-    MS_theoretical_mass = 1001117,
+    /// theoretical neutral mass: The theoretical neutral mass of the molecule (e.g. the peptide sequence and its modifications) not including its charge carrier.
+    MS_theoretical_neutral_mass = 1001117,
+
+    /// theoretical mass (theoretical neutral mass): The theoretical neutral mass of the molecule (e.g. the peptide sequence and its modifications) not including its charge carrier.
+    MS_theoretical_mass = MS_theoretical_neutral_mass,
 
     /// param: b ion: Parameter information, type of product: b ion with charge on the N-terminal side.
     MS_param__b_ion = 1001118,
@@ -4088,6 +4091,12 @@ enum PWIZ_API_DECL CVID
     /// search statistics: The details of the actual run of the search.
     MS_search_statistics = 1001184,
 
+    /// Mobilion MBI format: Mobilion MBI file format.
+    MS_Mobilion_MBI_format = 1001185,
+
+    /// Mobilion MBI nativeID format: Native format defined by frame=xsd:nonNegativeInteger scan=xsd:nonNegativeInteger.
+    MS_Mobilion_MBI_nativeID_format = 1001186,
+
     /// modification specificity peptide N-term: As parameter for search engine: apply the modification only at the N-terminus of a peptide.
     MS_modification_specificity_peptide_N_term = 1001189,
 
@@ -7568,8 +7577,11 @@ enum PWIZ_API_DECL CVID
     /// second-pass peptide identification: A putative identified peptide found in a second-pass search of protein sequences selected from a first-pass search.
     MS_second_pass_peptide_identification = 1002341,
 
-    /// MZmine: A framework for differential analysis of mass spectrometry data.
-    MS_MZmine = 1002342,
+    /// mzmine: A framework for differential analysis of mass spectrometry data.
+    MS_mzmine = 1002342,
+
+    /// MZmine (mzmine): A framework for differential analysis of mass spectrometry data.
+    MS_MZmine = MS_mzmine,
 
     /// ion stability type: Stability type of the ion.
     MS_ion_stability_type_OBSOLETE = 1002343,
@@ -10853,6 +10865,48 @@ enum PWIZ_API_DECL CVID
     /// electron beam energy: The kinetic energy of the electron beam used in dissociation methods induced by a free electron beam, such as electron-capture dissociation (ECD), electron-detachment dissociation (EDD), and electron-activated dissociation (EAD).
     MS_electron_beam_energy = 1003410,
 
+    /// Orbitrap IQ-X: Thermo Scientific Orbitrap IQ-X mass spectrometer with Tribrid architecture consisting of quadrupole mass filter, linear ion trap and Orbitrap mass analyzers.
+    MS_Orbitrap_IQ_X = 1003411,
+
+    /// timsTOF Ultra 2: Bruker Daltonics timsTOF Ultra 2.
+    MS_timsTOF_Ultra_2 = 1003412,
+
+    /// Kojak: Kojak open-source crosslinked peptide sequence search engine developed at the Institute for Systems Biology.
+    MS_Kojak = 1003413,
+
+    /// Kojak:score: The Kojak score for an individual peptide sequence, similar to Comet:xcorr.
+    MS_Kojak_score = 1003414,
+
+    /// Kojak:expectation value: The Kojak expectation value for an individual peptide sequence.
+    MS_Kojak_expectation_value = 1003415,
+
+    /// Kojak:matched ions: The number of matched ions for an individual peptide sequence in a Kojak result.
+    MS_Kojak_matched_ions = 1003416,
+
+    /// Kojak:consecutive matched ions: The highest run of consecutive matched ions for an individual peptide sequence in a Kojak result.
+    MS_Kojak_consecutive_matched_ions = 1003417,
+
+    /// Kojak:delta score: The difference between the top Kojak score and the next best Kojak score for a PSM.
+    MS_Kojak_delta_score = 1003418,
+
+    /// Kojak:rank: The rank of an individual peptide from the first pass of the Kojak scoring algorithm. Applies only to sequences in a crosslinked result.
+    MS_Kojak_rank = 1003419,
+
+    /// Kojak:score xlink: The Kojak score for a crosslinked pair of peptide sequences, similar to Comet:xcorr.
+    MS_Kojak_score_xlink = 1003420,
+
+    /// Kojak:expectation value xlink: The Kojak expectation value for a crosslinked pair of peptide sequences.
+    MS_Kojak_expectation_value_xlink = 1003421,
+
+    /// Kojak:matched ions xlink: The number of matched ions for a crosslinked pair of peptide sequences in a Kojak result.
+    MS_Kojak_matched_ions_xlink = 1003422,
+
+    /// Orbitrap Exploris GC 240: Orbitrap Exploris GC 240 Mass Spectrometer.
+    MS_Orbitrap_Exploris_GC_240 = 1003423,
+
+    /// selected fragment theoretical m/z observed intensity spectrum: Spectrum for which the peaks are limited to a subset of known product ions that are important for subsequent identification, whose m/z values are corrected to theoretical values, and intensity values are experimentally derived.
+    MS_selected_fragment_theoretical_m_z_observed_intensity_spectrum = 1003424,
+
     /// Number of Occurrences: The number of times something happened.
     NCIT_Number_of_Occurrences = 103150827,
 
@@ -10928,6 +10982,30 @@ enum PWIZ_API_DECL CVID
     /// environment metric: QC metric related to measurements of the ambient environment, such as the laboratory.
     MS_environment_metric = 4000024,
 
+    /// precursor ion current chromatogram: Representation of the ion current assigned to detected precursors in the series of all MS1 spectra versus time.
+    MS_precursor_ion_current_chromatogram = 4000025,
+
+    /// precursor ion chromatogram (precursor ion current chromatogram): Representation of the ion current assigned to detected precursors in the series of all MS1 spectra versus time.
+    MS_precursor_ion_chromatogram = MS_precursor_ion_current_chromatogram,
+
+    /// fragment ppm deviation median: The median of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied.
+    MS_fragment_ppm_deviation_median = 4000026,
+
+    /// fragment ppm deviation mean: The mean of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied
+    MS_fragment_ppm_deviation_mean = 4000027,
+
+    /// fragment ppm deviation sigma: The standard deviation of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied
+    MS_fragment_ppm_deviation_sigma = 4000028,
+
+    /// area under TIC in MS1: The area under the total ion current chromatogram (MS:1000235) of all MS1 spectra.
+    MS_area_under_TIC_in_MS1 = 4000029,
+
+    /// area under TIC in MS2: The area under the total ion current chromatogram (MS:1000235) of all MS2 spectra.
+    MS_area_under_TIC_in_MS2 = 4000030,
+
+    /// peak area of MS1 vs MS2 signal ratio: The ratio of the area under TIC of MS1 (MS:4000029) divided by the area under the TIC of MS2 (MS:4000030).
+    MS_peak_area_of_MS1_vs_MS2_signal_ratio = 4000031,
+
     /// XIC50 fraction: The number of XIC that account for the top half of all XIC-FWHM divided by the number of all XIC.
     MS_XIC50_fraction = 4000050,
 
@@ -15887,14 +15965,14 @@ enum PWIZ_API_DECL CVID
     /// DBIA: Desthiobiotinylation of cysteine with DBIA probe.
     UNIMOD_DBIA = 300002062,
 
-    /// Mono_Nγ-propargyl-L-Gln_desthiobiotin: Monomodification of Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide.
-    UNIMOD_Mono_N___propargyl_L_Gln_desthiobiotin = 300002067,
+    /// Mono_Ngamma-propargyl-L-Gln_desthiobiotin: Monomodification of Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide.
+    UNIMOD_Mono_Ngamma_propargyl_L_Gln_desthiobiotin = 300002067,
 
-    /// Di_L-Glu_Nγ-propargyl-L-Gln_desthiobiotin: Dimodification of L-Glu and Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide.
-    UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin = 300002068,
+    /// Di_L-Glu_Ngamma-propargyl-L-Gln_desthiobiotin: Dimodification of L-Glu and Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide.
+    UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin = 300002068,
 
-    /// Di_L-Gln_Nγ-propargyl-L-Gln_desthiobiotin: Dimodification of L-Gln and Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide.
-    UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin = 300002069,
+    /// Di_L-Gln_Ngamma-propargyl-L-Gln_desthiobiotin: Dimodification of L-Gln and Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide.
+    UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin = 300002069,
 
     /// L-Gln: Monomodification with glutamine.
     UNIMOD_L_Gln = 300002070,
@@ -15935,6 +16013,63 @@ enum PWIZ_API_DECL CVID
     /// Label:13C(2)15N(1): 13C(2) 15N(1) Silac label.
     UNIMOD_Label_13C_2_15N_1_ = 300002088,
 
+    /// DPIA: Desthiobiotinylation of cysteine with DPIA (Desthiobiotin polyethyleneoxide iodoacetamide) probe.
+    UNIMOD_DPIA = 300002106,
+
+    /// Acetoacetyl: Acetoacetylation.
+    UNIMOD_Acetoacetyl = 300002107,
+
+    /// Isovaleryl: Isovalerylation.
+    UNIMOD_Isovaleryl = 300002108,
+
+    /// 2-methylbutyryl: 2-methylbutyrylation.
+    UNIMOD_2_methylbutyryl = 300002109,
+
+    /// Tiglyl: Tiglylation.
+    UNIMOD_Tiglyl = 300002110,
+
+    /// 3-methylglutaryl: 3-methylglutarylation.
+    UNIMOD_3_methylglutaryl = 300002111,
+
+    /// 3-methylglutaconyl: 3-methylglutaconylation.
+    UNIMOD_3_methylglutaconyl = 300002112,
+
+    /// 3-hydroxy-3-methylglutaryl: 3-hydroxy-3-methylglutarylation.
+    UNIMOD_3_hydroxy_3_methylglutaryl = 300002113,
+
+    /// Lactylation: Lactylation(Lac).
+    UNIMOD_Lactylation = 300002114,
+
+    /// Pyruvoyl: Pyruvoylation.
+    UNIMOD_Pyruvoyl = 300002115,
+
+    /// Glyoxylyl: Glyoxylylation.
+    UNIMOD_Glyoxylyl = 300002116,
+
+    /// Itaconatyl: Itaconatylation.
+    UNIMOD_Itaconatyl = 300002117,
+
+    /// Itaconyl: Itaconylation.
+    UNIMOD_Itaconyl = 300002118,
+
+    /// ValGly: UFMylation residue.
+    UNIMOD_ValGly = 300002119,
+
+    /// Pentanoyl: Pentanoylation.
+    UNIMOD_Pentanoyl = 300002120,
+
+    /// Hexanoyl: Hexanoylation.
+    UNIMOD_Hexanoyl = 300002121,
+
+    /// Label:13C(6)15N(2)+TMT6plex: Sixplex Tandem Mass Tag 13C(6) 15N(2) Silac label.
+    UNIMOD_Label_13C_6_15N_2__TMT6plex = 300002122,
+
+    /// Label:13C(6)15N(2)+TMTpro: TMTpro Tandem Mass Tag 13C(6) 15N(2) Silac label.
+    UNIMOD_Label_13C_6_15N_2__TMTpro = 300002123,
+
+    /// 2PCA-triazole-ethanethiol: Cleaved 2PCA clicked to biotin-SS-azide.
+    UNIMOD_2PCA_triazole_ethanethiol = 300002126,
+
     /// unit: A unit of measurement is a standardized quantity of a physical quality.
     UO_unit = 400000000,
 
diff --git a/pwiz/data/common/psi-ms.obo b/pwiz/data/common/psi-ms.obo
index 3b372e9695..1f163b9175 100644
--- a/pwiz/data/common/psi-ms.obo
+++ b/pwiz/data/common/psi-ms.obo
@@ -1,6 +1,6 @@
 format-version: 1.2
-data-version: 4.1.163
-date: 19:07:2024 07:15
+data-version: 4.1.182
+date: 11:10:2024 07:15
 saved-by: Joshua Klein
 auto-generated-by: OBO-Edit 2.3.1
 default-namespace: MS
@@ -20,7 +20,7 @@ remark: creator: Pierre-Alain Binz <pierre-alain.binz <-at-> chuv.ch>
 remark: creator: Gerhard Mayer <mayerg97 <-at-> rub.de>
 remark: creator: Joshua Klein <jaklein <-at-> bu.edu>
 remark: creator: Chris Bielow <chris.bielow <-at-> fu-berlin.de>
-remark: creator: Wout Bittremieux <wbittremieux <-at-> health.ucsd.edu>
+remark: creator: Wout Bittremieux <wout.bittremieux <-at-> uantwerpen.be>
 remark: creator: Nils Hoffmann < nils.hoffmann <-at-> cebitec.uni-bielefeld.de>
 remark: creator: Julian Uszkoreit <julian.uszkoreit <-at-> ruhr-uni-bochum.de>
 remark: creator: Mathias Walzer <walzer <-at-> ebi.ac.uk>
@@ -7312,11 +7312,12 @@ is_a: MS:1001085 ! protein-level identification attribute
 
 [Term]
 id: MS:1001117
-name: theoretical mass
+name: theoretical neutral mass
 def: "The theoretical neutral mass of the molecule (e.g. the peptide sequence and its modifications) not including its charge carrier." [PSI:PI]
 is_a: MS:1001105 ! peptide sequence-level identification attribute
 relationship: has_units UO:0000221 ! dalton
 relationship: has_value_type xsd:double ! The allowed value-type for this CV term
+synonym: "theoretical mass" EXACT []
 
 [Term]
 id: MS:1001118
@@ -7742,6 +7743,18 @@ name: search statistics
 def: "The details of the actual run of the search." [PSI:PI]
 is_a: MS:1001405 ! spectrum identification result details
 
+[Term]
+id: MS:1001185
+name: Mobilion MBI format
+def: "Mobilion MBI file format." [PSI:MS]
+is_a: MS:1000560 ! mass spectrometer file format
+
+[Term]
+id: MS:1001186
+name: Mobilion MBI nativeID format
+def: "Native format defined by frame=xsd:nonNegativeInteger scan=xsd:nonNegativeInteger." [PSI:MS]
+is_a: MS:1000767 ! native spectrum identifier format
+
 [Term]
 id: MS:1001189
 name: modification specificity peptide N-term
@@ -14811,6 +14824,7 @@ id: MS:1002257
 name: Comet:expectation value
 def: "The Comet result 'Expectation value'." [PSI:PI]
 is_a: MS:1001153 ! search engine specific score
+is_a: MS:1001143 ! PSM-level search engine specific statistic
 relationship: has_value_type xsd:double ! The allowed value-type for this CV term
 
 [Term]
@@ -15377,8 +15391,9 @@ relationship: has_value_type xsd:boolean ! The allowed value-type for this CV te
 
 [Term]
 id: MS:1002342
-name: MZmine
+name: mzmine
 def: "A framework for differential analysis of mass spectrometry data." [PMID:16403790, PMID:20650010]
+synonym: "MZmine" EXACT []
 is_a: MS:1001456 ! analysis software
 is_a: MS:1001457 ! data processing software
 
@@ -15831,6 +15846,7 @@ is_a: MS:1002704 ! protein-level result list attribute
 is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000008 ! ID based metric
 relationship: has_value_type xsd:int ! The allowed value-type for this CV term
+relationship: has_units UO:0000189 ! count unit
 
 [Term]
 id: MS:1002405
@@ -20247,6 +20263,7 @@ id: MS:1003074
 name: predicted spectrum
 def: "Spectrum that originates from a compututational algorithm that attempts to predict spectra." [PSI:PI]
 is_a: MS:1003072 ! spectrum origin type
+is_a: MS:1003065 ! spectrum aggregation type
 
 [Term]
 id: MS:1003075
@@ -20994,7 +21011,7 @@ relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 id: MS:1003181
 name: combined dissociation method
 def: "Combination of two or more dissociation methods that are known by a special term." [PSI:PI]
-is_a: MS:1000044 ! dissociation method
+is_a: MS:1000510 ! precursor activation attribute
 
 [Term]
 id: MS:1003182
@@ -21453,6 +21470,7 @@ is_a: MS:1002702 ! peptide sequence-level result list attribute
 is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000008 ! ID based metric
 relationship: has_value_type xsd:int ! The allowed value-type for this CV term
+relationship: has_units UO:0000189 ! count unit
 
 [Term]
 id: MS:1003251
@@ -21462,6 +21480,7 @@ is_a: MS:1002700 ! PSM-level result list attribute
 is_a: MS:4000003 ! single value
 relationship: has_value_type xsd:int ! The allowed value-type for this CV term
 relationship: has_metric_category MS:4000008 ! ID based metric
+relationship: has_units UO:0000189 ! count unit
 
 [Term]
 id: MS:1003252
@@ -21475,6 +21494,7 @@ name: DIA-NN
 def: "A universal software for data-independent acquisition (DIA) proteomics data processing" [PMID:31768060, https://github.com/vdemichev/DiaNN]
 is_a: MS:1001139 ! quantitation software name
 is_a: MS:1001456 ! analysis software
+is_a: MS:1003207 ! library creation software
 
 [Term]
 id: MS:1003254
@@ -22515,6 +22535,20 @@ name: spectrum clustering software
 def: "Software designed to group multiple mass spectra by high similarity, generally with the goal of grouping replicate spectra derived from the same analyte." [PSI:MS]
 is_a: MS:1000531 ! software
 
+[Term]
+id: MS:1003407
+name: Scout
+def: "Identifying crosslinked peptides in complex protein mixtures" [PSI:MS]
+is_a: MS:1001456 ! analysis software
+
+[Term]
+id: MS:1003408
+name: Scout score
+def: "Scout identification search engine score" [PSI:MS]
+is_a: MS:1001143 ! PSM-level search engine specific statistic
+relationship: has_order MS:1003407 ! higher score better
+relationship: has_value_type xsd:double ! The allowed value-type for this CV term
+
 [Term]
 id: MS:1003409
 name: Stellar
@@ -22529,6 +22563,109 @@ is_a: MS:1000510 ! precursor activation attribute
 relationship: has_units UO:0000266 ! electronvolt
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 
+[Term]
+id: MS:1003411
+name: Orbitrap IQ-X
+def: "Thermo Scientific Orbitrap IQ-X mass spectrometer with Tribrid architecture consisting of quadrupole mass filter, linear ion trap and Orbitrap mass analyzers." [PSI:MS]
+is_a: MS:1000494 ! Thermo Scientific instrument model
+
+[Term]
+id: MS:1003412
+name: timsTOF Ultra 2
+def: "Bruker Daltonics timsTOF Ultra 2." [PSI:MS]
+is_a: MS:1003123 ! Bruker Daltonics timsTOF series
+
+[Term]
+id: MS:1003413
+name: Kojak
+def: "Kojak open-source crosslinked peptide sequence search engine developed at the Institute for Systems Biology." [PMID:36629399]
+is_a: MS:1001456 ! analysis software
+
+[Term]
+id: MS:1003414
+name: Kojak:score
+def: "The Kojak score for an individual peptide sequence, similar to Comet:xcorr." [PSI:PI]
+is_a: MS:1001143 ! PSM-level search engine specific statistic
+relationship: has_order MS:1002108 ! higher score better
+relationship: has_value_type xsd:double ! The allowed value-type for this CV term
+
+[Term]
+id: MS:1003415
+name: Kojak:expectation value
+def: "The Kojak expectation value for an individual peptide sequence." [PSI:PI]
+is_a: MS:1001153 ! search engine specific score
+is_a: MS:1001143 ! PSM-level search engine specific statistic
+relationship: has_order MS:1002109 ! lower score better
+relationship: has_value_type xsd:double ! The allowed value-type for this CV term
+
+[Term]
+id: MS:1003416
+name: Kojak:matched ions
+def: "The number of matched ions for an individual peptide sequence in a Kojak result." [PSI:PI]
+is_a: MS:1001143 ! PSM-level search engine specific statistic
+relationship: has_order MS:1002108 ! higher score better
+relationship: has_value_type xsd:int ! The allowed value-type for this CV term
+
+[Term]
+id: MS:1003417
+name: Kojak:consecutive matched ions
+def: "The highest run of consecutive matched ions for an individual peptide sequence in a Kojak result." [PSI:PI]
+is_a: MS:1001143 ! PSM-level search engine specific statistic
+relationship: has_order MS:1002108 ! higher score better
+relationship: has_value_type xsd:int ! The allowed value-type for this CV term
+
+[Term]
+id: MS:1003418
+name: Kojak:delta score
+def: "The difference between the top Kojak score and the next best Kojak score for a PSM." [PSI:PI]
+is_a: MS:1001143 ! PSM-level search engine specific statistic
+relationship: has_order MS:1002108 ! higher score better
+relationship: has_value_type xsd:double ! The allowed value-type for this CV term
+
+[Term]
+id: MS:1003419
+name: Kojak:rank
+def: "The rank of an individual peptide from the first pass of the Kojak scoring algorithm. Applies only to sequences in a crosslinked result." [PSI:PI]
+is_a: MS:1001143 ! PSM-level search engine specific statistic
+relationship: has_order MS:1002109 ! lower score better
+relationship: has_value_type xsd:int ! The allowed value-type for this CV term
+
+[Term]
+id: MS:1003420
+name: Kojak:score xlink
+def: "The Kojak score for a crosslinked pair of peptide sequences, similar to Comet:xcorr." [PSI:PI]
+is_a: MS:1001143 ! PSM-level search engine specific statistic
+relationship: has_order MS:1002108 ! higher score better
+relationship: has_value_type xsd:double ! The allowed value-type for this CV term
+
+[Term]
+id: MS:1003421
+name: Kojak:expectation value xlink
+def: "The Kojak expectation value for a crosslinked pair of peptide sequences." [PSI:PI]
+is_a: MS:1001153 ! search engine specific score
+is_a: MS:1001143 ! PSM-level search engine specific statistic
+relationship: has_order MS:1002109 ! lower score better
+relationship: has_value_type xsd:double ! The allowed value-type for this CV term
+
+[Term]
+id: MS:1003422
+name: Kojak:matched ions xlink
+def: "The number of matched ions for a crosslinked pair of peptide sequences in a Kojak result." [PSI:PI]
+is_a: MS:1001143 ! PSM-level search engine specific statistic
+relationship: has_order MS:1002108 ! higher score better
+relationship: has_value_type xsd:int ! The allowed value-type for this CV term
+
+[Term]
+id: MS:1003423
+name: Orbitrap Exploris GC 240
+def: "Orbitrap Exploris GC 240 Mass Spectrometer." [PSI:MS]
+is_a: MS:1000494 ! Thermo Scientific instrument model
+
+[Term]
+id: MS:1003424
+name: selected fragment theoretical m/z observed intensity spectrum
+def: "Spectrum for which the peaks are limited to a subset of known product ions that are important for subsequent identification, whose m/z values are corrected to theoretical values, and intensity values are experimentally derived." [PSI:PI]
+is_a: MS:1003072 ! spectrum origin type
 
 [Term]
 id: MS:4000000
@@ -22676,6 +22813,96 @@ name: environment metric
 def: "QC metric related to measurements of the ambient environment, such as the laboratory." [PSI:MS]
 is_a: MS:4000001 ! QC metric
 
+
+[Term]
+id: MS:4000025
+name: precursor ion current chromatogram
+def: "Representation of the ion current assigned to detected precursors in the series of all MS1 spectra versus time." [PSI:MS]
+synonym: "precursor ion chromatogram" EXACT []
+is_a: MS:1000810 ! ion current chromatogram
+is_a: MS:4000004 ! n-tuple
+relationship: has_metric_category MS:4000009 ! ID free metric
+relationship: has_metric_category MS:4000012 ! single run based metric
+relationship: has_metric_category MS:4000017 ! chromatogram metric
+relationship: has_metric_category MS:4000018 ! XIC metric
+relationship: has_metric_category MS:4000021 ! MS1 metric
+relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+
+
+[Term]
+id: MS:4000026
+name: fragment ppm deviation median
+def: "The median of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied." [PSI:MS]
+comment:  Factors like temperature, airflow, or instrument calibration can cause mass shifts.
+is_a: MS:4000003 ! single value
+relationship: has_metric_category MS:4000008 ! ID based metric
+relationship: has_metric_category MS:4000022 ! MS2 metric
+relationship: has_value_concept MS:1000014 ! accuracy
+relationship: has_units UO:0000169 ! parts per million
+relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000574 ! center value
+
+[Term]
+id: MS:4000027
+name: fragment ppm deviation mean
+def: "The mean of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied" [PSI:MS]
+comment:  Factors like temperature, airflow, or instrument calibration can cause mass shifts. See MS:4000178 for the MS1 equivalent.
+is_a: MS:4000003 ! single value
+relationship: has_metric_category MS:4000008 ! ID based metric
+relationship: has_metric_category MS:4000022 ! MS2 metric
+relationship: has_value_concept MS:1000014 ! accuracy
+relationship: has_units UO:0000169 ! parts per million
+relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000401 ! sample mean
+
+[Term]
+id: MS:4000028
+name: fragment ppm deviation sigma
+def: "The standard deviation of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied" [PSI:MS]
+comment:  Factors like temperature, airflow, or instrument calibration can cause mass shifts.  See MS:4000179 for the MS1 equivalent.
+is_a: MS:4000003 ! single value
+relationship: has_metric_category MS:4000008 ! ID based metric
+relationship: has_metric_category MS:4000022 ! MS2 metric
+relationship: has_value_concept MS:1000830 ! precision
+relationship: has_units UO:0000169 ! parts per million
+relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000237 ! standard deviation
+
+[Term]
+id: MS:4000029
+name: area under TIC in MS1
+def: "The area under the total ion current chromatogram (MS:1000235) of all MS1 spectra." [PSI:MS]
+comment: The metric informs about the dynamic range of the acquisition. Differences between samples of an experiment may indicate differences in the dynamic range and/or in the sample content. The signal can be affected by contamination, retention time shifts, or loss of hydrophilic/hydrophobic peptides.
+is_a: MS:4000003 ! single value
+relationship: has_metric_category MS:4000009 ! ID free
+relationship: has_metric_category MS:4000017 ! chromatogram metric
+relationship: has_metric_category MS:4000021 ! MS1 metric
+relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000209 ! area under curve
+
+[Term]
+id: MS:4000030
+name: area under TIC in MS2
+def: "The area under the total ion current chromatogram (MS:1000235) of all MS2 spectra." [PSI:MS]
+comment: The metric informs about the dynamic range of the acquisition. Differences between samples of an experiment may indicate differences in the dynamic range and/or in the sample content. The signal can be affected by contamination, retention time shifts, or loss of hydrophilic/hydrophobic peptides. Issues such as contamination on the MS front-end and fragmentation efficiency can lead to poor MS signals. Contamination would decrease both MS1 and MS2 S/N, while poor fragmentation efficiency affects MS2 signal but leaves MS1 signal unchanged.
+is_a: MS:4000003 ! single value
+relationship: has_metric_category MS:4000009 ! ID free
+relationship: has_metric_category MS:4000017 ! chromatogram metric
+relationship: has_metric_category MS:4000022 ! MS2 metric
+relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000209 ! area under curve
+
+[Term]
+id: MS:4000031
+name: peak area of MS1 vs MS2 signal ratio
+def: "The ratio of the area under TIC of MS1 (MS:4000029) divided by the area under the TIC of MS2 (MS:4000030)." [PSI:MS]
+comment: Poor fragmentation efficiency or precursor fragmentation intensity thresholds affect MS2 signal but leave MS1 signal unchanged.
+is_a: MS:4000003 ! single value
+is_a: MS:1001848 ! simple ratio of two values
+relationship: has_metric_category MS:4000009 ! ID free
+relationship: has_metric_category MS:4000017 ! chromatogram metric
+relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+
 [Term]
 id: MS:4000050
 name: XIC50 fraction
@@ -22686,7 +22913,7 @@ is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000012 ! single run based metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
-relationship: has_value_concept UO:0000191 ! fraction
+relationship: has_units UO:0000191 ! fraction
 
 [Term]
 id: MS:4000051
@@ -22701,6 +22928,8 @@ relationship: has_metric_category MS:4000012 ! single run based metric
 relationship: has_metric_category MS:4000018 ! XIC metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_value_concept MS:1000086 ! full width at half-maximum
+relationship: has_value_concept STATO:0000291 ! quantile
+relationship: has_units UO:0000010 ! second
 
 [Term]
 id: MS:4000052
@@ -22714,6 +22943,8 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000012 ! single run based metric
 relationship: has_metric_category MS:4000018 ! XIC metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000105 ! log signal intensity ratio
+relationship: has_units UO:0000191 ! fraction
 
 [Term]
 id: MS:4000053
@@ -22794,6 +23025,7 @@ relationship: has_metric_category MS:4000012 ! single run based metric
 relationship: has_metric_category MS:4000017 ! chromatogram metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000105 ! log signal intensity ratio
 
 [Term]
 id: MS:4000058
@@ -22809,6 +23041,7 @@ relationship: has_metric_category MS:4000012 ! single run based metric
 relationship: has_metric_category MS:4000017 ! chromatogram metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000105 ! log signal intensity ratio
 
 [Term]
 id: MS:4000059
@@ -22850,6 +23083,8 @@ relationship: has_metric_category MS:4000012 ! single run based metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:int ! The allowed value-type for this CV term
 relationship: has_value_concept NCIT:C45781 ! Density
+relationship: has_value_concept STATO:0000291 ! quantile
+relationship: has_units UO:0000189 ! count unit
 
 [Term]
 id: MS:4000062
@@ -22865,6 +23100,7 @@ relationship: has_metric_category MS:4000012 ! single run based metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:int ! The allowed value-type for this CV term
 relationship: has_value_concept NCIT:C45781 ! Density
+relationship: has_value_concept STATO:0000291 ! quantile
 relationship: has_units UO:0000189 ! count unit
 
 [Term]
@@ -22947,7 +23183,7 @@ name: spectra half-TIC
 def: "The minimal proportion of peaks needed to account for at least 50% of the total ion current in each individual spectrum considered, recorded in a mandatory fraction column. Either USI or native spectrum identifier columns must be present as well." [PSI:MS]
 is_a: MS:4000005 ! table
 relationship: has_metric_category MS:4000009 ! ID free metric
-relationship: has_metric_category MS:4000022 ! MS2 metric
+relationship: has_metric_category MS:4000019 ! MS metric
 relationship: has_metric_category MS:4000012 ! single run based metric
 relationship: has_optional_column MS:1003063 ! universal spectrum identifier
 relationship: has_optional_column MS:1000767 ! native spectrum identifier format
@@ -22964,6 +23200,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000012 ! single run based metric
 relationship: has_metric_category MS:4000019 ! MS metric
 relationship: has_units MS:1000040 ! m/z
+relationship: has_value_concept STATO:0000035 ! range
 
 [Term]
 id: MS:4000070
@@ -22975,6 +23212,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000012 ! single run based metric
 relationship: has_metric_category MS:4000016 ! retention time metric
 relationship: has_units UO:0000010 ! second
+relationship: has_value_concept STATO:0000035 ! range
 
 [Term]
 id: MS:4000071
@@ -23374,6 +23612,7 @@ is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000401 ! sample mean
 
 [Term]
 id: MS:4000109
@@ -23384,6 +23623,7 @@ is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000237 ! standard deviation
 
 [Term]
 id: MS:4000110
@@ -23394,6 +23634,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000111
@@ -23404,6 +23645,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000112
@@ -23414,6 +23656,7 @@ is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000401 ! sample mean
 
 [Term]
 id: MS:4000113
@@ -23424,6 +23667,7 @@ is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000237 ! standard deviation
 
 [Term]
 id: MS:4000114
@@ -23434,6 +23678,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000115
@@ -23444,6 +23689,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000116
@@ -23455,6 +23701,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000291 ! quantile
 
 [Term]
 id: MS:4000117
@@ -23466,6 +23713,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000401 ! sample mean
 
 [Term]
 id: MS:4000118
@@ -23477,6 +23725,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000237 ! standard deviation
 
 [Term]
 id: MS:4000119
@@ -23488,6 +23737,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000120
@@ -23499,6 +23749,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000121
@@ -23509,6 +23760,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000291 ! quantile
 
 [Term]
 id: MS:4000122
@@ -23519,6 +23771,7 @@ is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000401 ! sample mean
 
 [Term]
 id: MS:4000123
@@ -23529,6 +23782,7 @@ is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000237 ! standard deviation
 
 [Term]
 id: MS:4000124
@@ -23539,6 +23793,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000125
@@ -23549,6 +23804,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000126
@@ -23559,6 +23815,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000291 ! quantile
 
 [Term]
 id: MS:4000127
@@ -23569,6 +23826,7 @@ is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000401 ! sample mean
 
 [Term]
 id: MS:4000128
@@ -23579,6 +23837,7 @@ is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000237 ! standard deviation
 
 [Term]
 id: MS:4000129
@@ -23589,6 +23848,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000130
@@ -23599,6 +23859,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000131
@@ -23609,6 +23870,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_units UO:0000028 ! millisecond
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000291 ! quantile
 
 [Term]
 id: MS:4000132
@@ -23620,6 +23882,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_units UO:0000028 ! millisecond
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000401 ! sample mean
 
 [Term]
 id: MS:4000133
@@ -23631,6 +23894,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_units UO:0000028 ! millisecond
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000237 ! standard deviation
 
 [Term]
 id: MS:4000134
@@ -23642,6 +23906,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_units UO:0000028 ! millisecond
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000135
@@ -23653,6 +23918,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_units UO:0000028 ! millisecond
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000136
@@ -23663,6 +23929,7 @@ is_a: MS:4000004 ! n-tuple
 relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_units UO:0000028 ! millisecond
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000291 ! quantile
 
 [Term]
 id: MS:4000137
@@ -23674,6 +23941,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_units UO:0000028 ! millisecond
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000401 ! sample mean
 
 [Term]
 id: MS:4000138
@@ -23685,6 +23953,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_units UO:0000028 ! millisecond
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000237 ! standard deviation
 
 [Term]
 id: MS:4000139
@@ -23696,6 +23965,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_units UO:0000028 ! millisecond
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000140
@@ -23707,6 +23977,7 @@ relationship: has_metric_category MS:4000009 ! ID free metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_units UO:0000028 ! millisecond
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000036 ! outlier
 
 [Term]
 id: MS:4000141
@@ -23877,6 +24148,7 @@ relationship: has_metric_category MS:4000008 ! ID based metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000291 ! quantile
 
 [Term]
 id: MS:4000162
@@ -23888,6 +24160,7 @@ relationship: has_metric_category MS:4000008 ! ID based metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000291 ! quantile
 
 [Term]
 id: MS:4000163
@@ -23899,6 +24172,7 @@ relationship: has_metric_category MS:4000008 ! ID based metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000401 ! sample mean
 
 [Term]
 id: MS:4000164
@@ -23910,6 +24184,7 @@ relationship: has_metric_category MS:4000008 ! ID based metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000401 ! sample mean
 
 [Term]
 id: MS:4000165
@@ -23921,6 +24196,7 @@ relationship: has_metric_category MS:4000008 ! ID based metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000237 ! standard deviation
 
 [Term]
 id: MS:4000166
@@ -23932,6 +24208,7 @@ relationship: has_metric_category MS:4000008 ! ID based metric
 relationship: has_metric_category MS:4000022 ! MS2 metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
 relationship: has_units MS:1000043 ! intensity unit
+relationship: has_value_concept STATO:0000237 ! standard deviation
 
 [Term]
 id: MS:4000167
@@ -24103,6 +24380,7 @@ comment: "High values may indicate a sample handling issue, and/or insufficient
 is_a: MS:4000003 ! single value
 relationship: has_metric_category MS:4000008 ! ID based metric
 relationship: has_value_type xsd:float ! The allowed value-type for this CV
+relationship: has_units UO:0000191 ! fraction
 relationship: has_domain MS:1002305 ! value between 0 and 1 inclusive
 relationship: has_order MS:1002109 ! lower score better
 synonym: "PG: Contaminants" NARROW []
@@ -24117,6 +24395,7 @@ relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_concept MS:1000014 ! accuracy
 relationship: has_units UO:0000169 ! parts per million
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000401 ! sample mean
 
 [Term]
 id: MS:4000179
@@ -24128,6 +24407,7 @@ relationship: has_metric_category MS:4000021 ! MS1 metric
 relationship: has_value_concept MS:1000830 ! precision
 relationship: has_units UO:0000169 ! parts per million
 relationship: has_value_type xsd:float ! The allowed value-type for this CV term
+relationship: has_value_concept STATO:0000237 ! standard deviation
 
 [Term]
 id: MS:4000180
@@ -24155,20 +24435,6 @@ synonym: "RT-MSMS-Q2" RELATED [PMID:24494671]
 synonym: "RT-MSMS-Q3" RELATED [PMID:24494671]
 synonym: "RT-MSMS-Q4" RELATED [PMID:24494671]
 
-[Term]
-id: MS:1003407
-name: Scout
-def: "Identifying crosslinked peptides in complex protein mixtures" [PSI:MS]
-is_a: MS:1001456 ! analysis software
-
-[Term]
-id: MS:1003408
-name: Scout score
-def: "Scout identification search engine score" [PSI:MS]
-is_a: MS:1001143 ! PSM-level search engine specific statistic
-relationship: has_order MS:1003407 ! higher score better
-relationship: has_value_type xsd:double ! The allowed value-type for this CV term
-
 [Term]
 id: PEFF:0000001
 name: PEFF CV term
@@ -25100,5 +25366,3 @@ synonym: "A^[2]" RELATED []
 is_a: UO:0000047
 created_by: gkoutos
 creation_date: 2013-06-27T05:06:40Z
-
-
diff --git a/pwiz/data/common/unimod.obo b/pwiz/data/common/unimod.obo
index c202b3bab2..7c282fe289 100644
--- a/pwiz/data/common/unimod.obo
+++ b/pwiz/data/common/unimod.obo
@@ -1,5 +1,5 @@
 format-version: 1.4
-date: 29:02:2024 10:49
+date: 12:08:2024 11:33
 
 saved-by: psi-pi_team
 default-namespace: UNIMOD
@@ -680,7 +680,7 @@ xref: delta_composition "H(5) C(3) N O"
 xref: username_of_poster "unimod"
 xref: group_of_poster "admin"
 xref: date_time_posted "2002-08-19 19:17:11"
-xref: date_time_modified "2010-12-21 16:57:03"
+xref: date_time_modified "2024-08-12 09:49:28"
 xref: approved "1"
 xref: spec_1_group "1"
 xref: spec_1_hidden "0"
@@ -1413,7 +1413,7 @@ is_a: UNIMOD:0 ! unimod root node
 [Term]
 id: UNIMOD:43
 name: HexNAc
-def: "N-Acetylhexosamine." [RESID:AA0151, FindMod:GLCN, RESID:AA0155, PMID:3086323, RESID:AA0154, URL:https\://glyconnect.expasy.org/browser/global/compositions/search?hexnac=1&mode=exact, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=43]
+def: "N-Acetylhexosamine." [FindMod:GLCN, RESID:AA0155, PMID:3086323, RESID:AA0154, RESID:AA0151, URL:https\://glyconnect.expasy.org/browser/global/compositions/search?hexnac=1&mode=exact, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=43]
 comment: The amine derivative of a hexose formed by replacing a hydroxyl group with an amino group.(+acetyl group).
 xref: record_id "43"
 xref: delta_mono_mass "203.079373"
@@ -1422,7 +1422,7 @@ xref: delta_composition "HexNAc"
 xref: username_of_poster "unimod"
 xref: group_of_poster "admin"
 xref: date_time_posted "2002-08-19 19:17:11"
-xref: date_time_modified "2017-03-30 14:45:58"
+xref: date_time_modified "2024-08-12 09:50:41"
 xref: approved "1"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -1455,14 +1455,14 @@ xref: spec_2_hidden "1"
 xref: spec_2_site "S"
 xref: spec_2_position "Anywhere"
 xref: spec_2_classification "O-linked glycosylation"
-xref: spec_2_neutral_loss_0_mono_mass "0"
-xref: spec_2_neutral_loss_0_avge_mass "0"
-xref: spec_2_neutral_loss_0_flag "false"
-xref: spec_2_neutral_loss_0_composition "0"
 xref: spec_2_neutral_loss_204_mono_mass "203.079373"
 xref: spec_2_neutral_loss_204_avge_mass "203.1925"
 xref: spec_2_neutral_loss_204_flag "false"
 xref: spec_2_neutral_loss_204_composition "HexNAc"
+xref: spec_2_neutral_loss_0_mono_mass "0"
+xref: spec_2_neutral_loss_0_avge_mass "0"
+xref: spec_2_neutral_loss_0_flag "false"
+xref: spec_2_neutral_loss_0_composition "0"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
 xref: spec_3_site "C"
@@ -1721,7 +1721,7 @@ is_a: UNIMOD:0 ! unimod root node
 [Term]
 id: UNIMOD:53
 name: HNE
-def: "4-hydroxynonenal (HNE)." [PMID:11327326, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=53]
+def: "4-hydroxynonenal (HNE)." [PMID:11327326, PMID:15276160, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=53]
 comment: A lipid-type modification. HNE forms a Michael addition product on Cysteine, Histidine and Lysines. Unusually, it doesn\'t replace a hydrogen on the amino acid side chain.
 xref: record_id "53"
 xref: delta_mono_mass "156.11503"
@@ -1730,7 +1730,7 @@ xref: delta_composition "H(16) C(9) O(2)"
 xref: username_of_poster "unimod"
 xref: group_of_poster "admin"
 xref: date_time_posted "2002-08-19 19:17:11"
-xref: date_time_modified "2012-03-09 11:21:00"
+xref: date_time_modified "2024-06-27 09:30:34"
 xref: approved "1"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -1759,6 +1759,11 @@ xref: spec_5_site "L"
 xref: spec_5_position "Anywhere"
 xref: spec_5_classification "Post-translational"
 xref: spec_5_misc_notes "GFAP from human brain tissues"
+xref: spec_6_group "6"
+xref: spec_6_hidden "1"
+xref: spec_6_site "R"
+xref: spec_6_position "Anywhere"
+xref: spec_6_classification "Post-translational"
 is_a: UNIMOD:0 ! unimod root node
 
 
@@ -4667,7 +4672,7 @@ xref: delta_composition "H(13) C(10) N(5) O(9) P(2) Pent"
 xref: username_of_poster "ionjockey"
 xref: group_of_poster "users"
 xref: date_time_posted "2004-05-27 20:53:37"
-xref: date_time_modified "2017-11-23 14:29:45"
+xref: date_time_modified "2024-08-12 09:51:41"
 xref: approved "1"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -4741,7 +4746,7 @@ id: UNIMOD:214
 name: iTRAQ4plex
 def: "Representative mass and accurate mass for 116 & 117." [URL:http\://docs.appliedbiosystems.com/pebiodocs/04351918.pdf, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=214]
 comment: Different channels have the same nominal mass but slightly different exact masses. Use this value for all channels for quantitation purposes. mTRAQ heavy is identical to iTRAQ4plex 117.
-synonym: "AKA iTRAQ4plex116/7 Applied Biosystems iTRAQ(TM) multiplexed quantitation chemistry" RELATED []
+synonym: "Applied Biosystems iTRAQ(TM) multiplexed quantitation chemistry AKA iTRAQ4plex116/7" RELATED []
 xref: record_id "214"
 xref: delta_mono_mass "144.102063"
 xref: delta_avge_mass "144.1544"
@@ -4749,7 +4754,7 @@ xref: delta_composition "H(12) C(4) 13C(3) N 15N O"
 xref: username_of_poster "unimod"
 xref: group_of_poster "admin"
 xref: date_time_posted "2004-06-08 14:04:07"
-xref: date_time_modified "2017-11-09 09:35:25"
+xref: date_time_modified "2024-08-12 09:52:54"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "0"
@@ -7526,7 +7531,7 @@ xref: delta_composition "H(4) C(3) O(2)"
 xref: username_of_poster "unimod"
 xref: group_of_poster "admin"
 xref: date_time_posted "2005-10-07 22:18:20"
-xref: date_time_modified "2021-02-09 10:33:42"
+xref: date_time_modified "2024-08-12 10:05:50"
 xref: approved "1"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -8039,7 +8044,7 @@ is_a: UNIMOD:0 ! unimod root node
 [Term]
 id: UNIMOD:405
 name: Phosphoadenosine
-def: "AMP." [RESID:AA0371, RESID:AA0227, RESID:AA0203, RESID:AA0267, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=405]
+def: "AMP." [RESID:AA0267, RESID:AA0203, RESID:AA0371, RESID:AA0227, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=405]
 xref: record_id "405"
 xref: delta_mono_mass "329.05252"
 xref: delta_avge_mass "329.2059"
@@ -8047,7 +8052,7 @@ xref: delta_composition "H(12) C(10) N(5) O(6) P"
 xref: username_of_poster "unimod"
 xref: group_of_poster "admin"
 xref: date_time_posted "2005-10-11 21:34:01"
-xref: date_time_modified "2021-03-11 13:32:18"
+xref: date_time_modified "2024-08-12 10:05:28"
 xref: approved "1"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -8076,14 +8081,14 @@ xref: spec_3_hidden "1"
 xref: spec_3_site "T"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Post-translational"
-xref: spec_3_neutral_loss_0_mono_mass "0"
-xref: spec_3_neutral_loss_0_avge_mass "0"
-xref: spec_3_neutral_loss_0_flag "false"
-xref: spec_3_neutral_loss_0_composition "0"
 xref: spec_3_neutral_loss_348_mono_mass "347.063085"
 xref: spec_3_neutral_loss_348_avge_mass "347.2212"
 xref: spec_3_neutral_loss_348_flag "false"
 xref: spec_3_neutral_loss_348_composition "H(14) C(10) N(5) O(7) P"
+xref: spec_3_neutral_loss_0_mono_mass "0"
+xref: spec_3_neutral_loss_0_avge_mass "0"
+xref: spec_3_neutral_loss_0_flag "false"
+xref: spec_3_neutral_loss_0_composition "0"
 xref: spec_4_group "4"
 xref: spec_4_hidden "1"
 xref: spec_4_site "H"
@@ -10354,7 +10359,7 @@ xref: delta_composition "H(12) C(5) 13C(2) N(2) 18O"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2006-10-16 13:46:49"
-xref: date_time_modified "2017-11-09 09:36:24"
+xref: date_time_modified "2024-08-12 09:55:37"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -10394,7 +10399,7 @@ xref: delta_composition "H(12) C(6) 13C N 15N 18O"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2006-10-16 13:48:16"
-xref: date_time_modified "2017-11-09 09:34:04"
+xref: date_time_modified "2024-08-12 09:55:49"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -13685,7 +13690,7 @@ xref: delta_composition "H(3) C(6) N O"
 xref: username_of_poster "verena-meyer"
 xref: group_of_poster ""
 xref: date_time_posted "2006-12-04 16:04:56"
-xref: date_time_modified "2014-07-09 16:57:01"
+xref: date_time_modified "2024-08-12 10:05:07"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -13711,7 +13716,7 @@ xref: delta_composition "H 2H(3) C(6) N O"
 xref: username_of_poster "verena-meyer"
 xref: group_of_poster ""
 xref: date_time_posted "2006-12-04 16:12:54"
-xref: date_time_modified "2014-07-09 16:57:50"
+xref: date_time_modified "2024-08-12 10:04:46"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -14063,7 +14068,7 @@ xref: delta_composition "H(24) C(7) 13C(7) N(3) 15N O(3)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2007-01-11 09:53:13"
-xref: date_time_modified "2017-11-09 09:38:11"
+xref: date_time_modified "2024-08-12 09:56:06"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "0"
@@ -14126,7 +14131,7 @@ xref: delta_composition "H(24) C(8) 13C(6) N(2) 15N(2) O(3)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2007-01-11 09:56:21"
-xref: date_time_modified "2017-11-09 09:37:18"
+xref: date_time_modified "2024-08-12 09:56:28"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -14246,9 +14251,9 @@ is_a: UNIMOD:0 ! unimod root node
 [Term]
 id: UNIMOD:737
 name: TMT6plex
-def: "Sixplex Tandem Mass Tag®." [URL:https\://www.piercenet.com/instructions/2162073.pdf, URL:http\://www.piercenet.com/instructions/2162457.pdf, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=737]
+def: "Sixplex Tandem Mass Tag®." [URL:http\://www.piercenet.com/instructions/2162457.pdf, URL:https\://www.piercenet.com/instructions/2162073.pdf, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=737]
 comment: M/z values of the TMT® fragment ions to be quantified for 6plex and 10plex: 126.12773 127.12476 128.13443 129.13147 130.14114 131.13818. Additional m/z values for 10plex: 127.13108 128.12811 129.13779 130.13482.
-synonym: "Tandem Mass Tag® and TMT® are registered Trademarks of Proteome Sciences plc. Also applies to TMT10plex Tandem Mass Tag sixplex labelling kit Proteome Sciences This is a nominal. representative mass" RELATED []
+synonym: "Tandem Mass Tag sixplex labelling kit Proteome Sciences Also applies to TMT10plex Tandem Mass Tag® and TMT® are registered Trademarks of Proteome Sciences plc. This is a nominal. representative mass" RELATED []
 xref: record_id "737"
 xref: delta_mono_mass "229.162932"
 xref: delta_avge_mass "229.2634"
@@ -14256,7 +14261,7 @@ xref: delta_composition "H(20) C(8) 13C(4) N 15N O(2)"
 xref: username_of_poster "JUergen.schaefer"
 xref: group_of_poster ""
 xref: date_time_posted "2007-03-01 13:44:23"
-xref: date_time_modified "2014-11-08 15:20:24"
+xref: date_time_modified "2024-08-12 10:10:11"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "0"
@@ -14296,7 +14301,7 @@ id: UNIMOD:738
 name: TMT2plex
 def: "Duplex Tandem Mass Tag®." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=738]
 comment: Duplex-TMT® reagents 2TMT-126, 2TMT-127. m/z values of the TMT® fragment ions to be quantified: 126.12773 127.13108.
-synonym: "Tandem Mass Tag® and TMT® are registered Trademarks of Proteome Sciences plc. Tandem Mass Tag Duplex labelling kit Proteome Sciences" RELATED []
+synonym: "Tandem Mass Tag Duplex labelling kit Proteome Sciences Tandem Mass Tag® and TMT® are registered Trademarks of Proteome Sciences plc." RELATED []
 xref: record_id "738"
 xref: delta_mono_mass "225.155833"
 xref: delta_avge_mass "225.2921"
@@ -14304,7 +14309,7 @@ xref: delta_composition "H(20) C(11) 13C N(2) O(2)"
 xref: username_of_poster "JUergen.schaefer"
 xref: group_of_poster ""
 xref: date_time_posted "2007-03-01 13:53:36"
-xref: date_time_modified "2014-11-08 15:19:53"
+xref: date_time_modified "2024-08-12 10:09:41"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "0"
@@ -14352,7 +14357,7 @@ xref: delta_composition "H(20) C(12) N(2) O(2)"
 xref: username_of_poster "JUergen.schaefer"
 xref: group_of_poster ""
 xref: date_time_posted "2007-03-02 09:29:50"
-xref: date_time_modified "2011-11-25 11:15:14"
+xref: date_time_modified "2024-08-12 10:08:55"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -14520,7 +14525,7 @@ xref: delta_composition "H(2) C(3) O(3)"
 xref: username_of_poster "massy"
 xref: group_of_poster ""
 xref: date_time_posted "2007-05-17 14:17:42"
-xref: date_time_modified "2017-04-03 10:51:25"
+xref: date_time_modified "2024-06-27 10:17:31"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -14537,6 +14542,10 @@ xref: spec_3_hidden "1"
 xref: spec_3_site "K"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Post-translational"
+xref: spec_3_neutral_loss_44_mono_mass "43.989829"
+xref: spec_3_neutral_loss_44_avge_mass "44.0095"
+xref: spec_3_neutral_loss_44_flag "false"
+xref: spec_3_neutral_loss_44_composition "C O(2)"
 is_a: UNIMOD:0 ! unimod root node
 
 
@@ -16828,7 +16837,7 @@ xref: delta_composition "H(8) C(6) O(4)"
 xref: username_of_poster "kimzey"
 xref: group_of_poster ""
 xref: date_time_posted "2010-01-15 18:19:17"
-xref: date_time_modified "2010-01-18 13:20:51"
+xref: date_time_modified "2024-08-12 10:04:25"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -17401,7 +17410,7 @@ xref: delta_composition "H(25) C(14) N(3) O(2) S"
 xref: username_of_poster "jorogers6"
 xref: group_of_poster ""
 xref: date_time_posted "2010-04-22 21:57:44"
-xref: date_time_modified "2014-11-08 16:06:08"
+xref: date_time_modified "2024-08-12 10:07:56"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -17424,7 +17433,7 @@ xref: delta_composition "H(25) C(10) 13C(4) N(2) 15N O(2) S"
 xref: username_of_poster "jorogers6"
 xref: group_of_poster ""
 xref: date_time_posted "2010-04-22 22:05:46"
-xref: date_time_modified "2016-09-22 14:38:08"
+xref: date_time_modified "2024-08-12 10:07:35"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -17521,7 +17530,7 @@ xref: delta_composition "H(-1) N(-1)"
 xref: username_of_poster "suckau"
 xref: group_of_poster ""
 xref: date_time_posted "2010-06-08 09:42:52"
-xref: date_time_modified "2010-06-28 10:47:55"
+xref: date_time_modified "2024-08-12 11:27:50"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -18031,7 +18040,7 @@ xref: delta_composition "H(5) C(3) N O(2)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2010-12-21 17:00:41"
-xref: date_time_modified "2010-12-21 17:00:41"
+xref: date_time_modified "2024-08-12 09:49:53"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -18551,7 +18560,7 @@ xref: delta_composition "H(9) C(4) N"
 xref: username_of_poster "cbarrero"
 xref: group_of_poster ""
 xref: date_time_posted "2011-06-15 12:04:35"
-xref: date_time_modified "2015-01-12 16:03:08"
+xref: date_time_modified "2024-08-12 10:11:43"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -23568,7 +23577,7 @@ xref: delta_composition "H(7) C(4) N O(2) S"
 xref: username_of_poster "alejandro"
 xref: group_of_poster ""
 xref: date_time_posted "2011-09-15 19:36:44"
-xref: date_time_modified "2011-09-23 16:33:31"
+xref: date_time_modified "2024-08-12 10:20:05"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -23827,7 +23836,7 @@ xref: delta_composition "H(6) C(4) O"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2011-11-21 12:06:20"
-xref: date_time_modified "2011-11-21 12:06:20"
+xref: date_time_modified "2024-08-12 10:01:08"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -24554,7 +24563,7 @@ xref: delta_composition "H(15) C(7) 13C 15N 18O"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2012-02-15 12:05:08"
-xref: date_time_modified "2012-02-15 12:05:08"
+xref: date_time_modified "2024-08-12 10:00:50"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -24588,7 +24597,7 @@ xref: delta_composition "H(13) 2H(2) C(8) N 18O"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2012-02-15 12:05:48"
-xref: date_time_modified "2016-09-22 15:14:06"
+xref: date_time_modified "2024-08-12 10:00:31"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -24621,7 +24630,7 @@ xref: delta_composition "H(13) 2H(2) C(7) 13C 15N O"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2012-02-15 12:06:10"
-xref: date_time_modified "2012-02-15 12:06:10"
+xref: date_time_modified "2024-08-12 10:00:14"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -24654,7 +24663,7 @@ xref: delta_composition "H(11) 2H(4) C(8) N O"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2012-02-15 12:06:30"
-xref: date_time_modified "2012-02-15 12:06:30"
+xref: date_time_modified "2024-08-12 09:59:49"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -24835,7 +24844,7 @@ id: UNIMOD:1341
 name: iodoTMT
 def: "Native iodoacetyl Tandem Mass Tag®." [URL:http\://www.lifetechnologies.com/order/catalog/product/90100, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=1341]
 comment: This modification describes the native iodoTMT Reagent without isotopic label. Upon CID, this reagent releases a reporter ion of 126.127725(monoisotopic mass).
-synonym: "iodoTMTzero iodoTMT0 Tandem Mass Tag® and TMT® are registered Trademarks of Proteome Sciences plc." RELATED []
+synonym: "Tandem Mass Tag® and TMT® are registered Trademarks of Proteome Sciences plc. iodoTMTzero iodoTMT0" RELATED []
 xref: record_id "1341"
 xref: delta_mono_mass "324.216141"
 xref: delta_avge_mass "324.4185"
@@ -24843,7 +24852,7 @@ xref: delta_composition "H(28) C(16) N(4) O(3)"
 xref: username_of_poster "rbomgard"
 xref: group_of_poster ""
 xref: date_time_posted "2012-07-06 17:37:43"
-xref: date_time_modified "2015-04-20 16:12:53"
+xref: date_time_modified "2024-08-12 10:07:13"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -24878,7 +24887,7 @@ id: UNIMOD:1342
 name: iodoTMT6plex
 def: "Sixplex iodoacetyl Tandem Mass Tag®." [URL:http\://www.lifetechnologies.com/order/catalog/product/90102, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=1342]
 comment: This modification describes the native iodoTMT Reagent without isotopic label. Upon CID, this reagent releases a reporter ions of 126.127725, 127.124760, 128.134433, 129.131468, 130.141141, and 131.138176 (monoisotopic mass).
-synonym: "iodoTMTsixplex iodoTMT6 Tandem Mass Tag® and TMT® are registered Trademarks of Proteome Sciences plc." RELATED []
+synonym: "Tandem Mass Tag® and TMT® are registered Trademarks of Proteome Sciences plc. iodoTMTsixplex iodoTMT6" RELATED []
 xref: record_id "1342"
 xref: delta_mono_mass "329.226595"
 xref: delta_avge_mass "329.3825"
@@ -24886,7 +24895,7 @@ xref: delta_composition "H(28) C(12) 13C(4) N(3) 15N O(3)"
 xref: username_of_poster "rbomgard"
 xref: group_of_poster ""
 xref: date_time_posted "2012-07-06 17:43:59"
-xref: date_time_modified "2015-04-20 16:13:35"
+xref: date_time_modified "2024-08-12 10:06:50"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -25076,7 +25085,7 @@ xref: delta_composition "H(9) C(5) O(7) P"
 xref: username_of_poster "BThomas"
 xref: group_of_poster ""
 xref: date_time_posted "2012-09-19 14:16:08"
-xref: date_time_modified "2015-04-29 11:15:49"
+xref: date_time_modified "2024-08-12 09:59:28"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -25130,7 +25139,7 @@ xref: delta_composition "H(4) C(4) O"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2012-12-24 15:50:10"
-xref: date_time_modified "2017-10-09 15:45:52"
+xref: date_time_modified "2024-08-12 09:59:07"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -26501,7 +26510,7 @@ xref: delta_composition "H(23) C(10) N(3)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2015-01-12 16:07:00"
-xref: date_time_modified "2015-01-12 16:07:00"
+xref: date_time_modified "2024-08-12 10:11:23"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -26522,7 +26531,7 @@ xref: delta_composition "H(16) C(7) N(2)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2015-01-12 16:08:04"
-xref: date_time_modified "2015-01-12 16:08:04"
+xref: date_time_modified "2024-08-12 10:11:10"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -40533,7 +40542,7 @@ is_a: UNIMOD:0 ! unimod root node
 id: UNIMOD:1831
 name: Tris
 def: "Tris adduct causes 104 Da addition at asparagine-succinimide intermediate." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=1831]
-synonym: "tris adduct at asparagine tris adduct at IgG causes 104 Da addition" RELATED []
+synonym: "tris adduct at IgG causes 104 Da addition tris adduct at asparagine" RELATED []
 xref: record_id "1831"
 xref: delta_mono_mass "104.071154"
 xref: delta_avge_mass "104.1277"
@@ -40541,7 +40550,7 @@ xref: delta_composition "H(10) C(4) N O(2)"
 xref: username_of_poster "pradeepnpraveen"
 xref: group_of_poster ""
 xref: date_time_posted "2016-08-04 12:54:25"
-xref: date_time_modified "2016-09-23 13:48:56"
+xref: date_time_modified "2024-08-12 09:58:49"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -40719,7 +40728,7 @@ xref: delta_composition "H(30) C(25) N(2) O(6)"
 xref: username_of_poster "shartson"
 xref: group_of_poster ""
 xref: date_time_posted "2016-08-26 19:59:17"
-xref: date_time_modified "2017-01-31 10:02:08"
+xref: date_time_modified "2024-08-12 10:21:44"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -40933,16 +40942,16 @@ xref: delta_composition "H(-3) Fe"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2017-06-15 12:58:58"
-xref: date_time_modified "2017-06-15 12:58:58"
+xref: date_time_modified "2024-08-12 09:58:26"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
-xref: spec_1_site "D"
+xref: spec_1_site "E"
 xref: spec_1_position "Anywhere"
 xref: spec_1_classification "Artefact"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
-xref: spec_1_site "E"
+xref: spec_1_site "D"
 xref: spec_1_position "Anywhere"
 xref: spec_1_classification "Artefact"
 xref: spec_2_group "2"
@@ -40964,7 +40973,7 @@ xref: delta_composition "H(8) C(4) O(2) S(2)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2017-06-15 14:09:46"
-xref: date_time_modified "2017-06-15 14:12:47"
+xref: date_time_modified "2024-08-12 09:58:02"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -41251,7 +41260,7 @@ xref: delta_composition "H(5) C(5) N O(2)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2017-08-18 09:34:59"
-xref: date_time_modified "2024-01-26 11:13:51"
+xref: date_time_modified "2024-08-12 10:24:12"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -41265,12 +41274,12 @@ xref: spec_2_position "Protein N-term"
 xref: spec_2_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "S"
+xref: spec_3_site "T"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "T"
+xref: spec_3_site "S"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
@@ -41292,7 +41301,7 @@ xref: delta_composition "H(7) C(4) N O"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2017-08-18 09:36:27"
-xref: date_time_modified "2024-01-26 11:12:21"
+xref: date_time_modified "2024-08-12 10:23:55"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -41306,12 +41315,12 @@ xref: spec_2_position "Protein N-term"
 xref: spec_2_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "S"
+xref: spec_3_site "T"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "T"
+xref: spec_3_site "S"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
@@ -41333,7 +41342,7 @@ xref: delta_composition "H(15) C(9) N(3) O(3)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2017-08-18 09:38:52"
-xref: date_time_modified "2024-01-26 11:16:24"
+xref: date_time_modified "2024-08-12 10:23:37"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -41347,12 +41356,12 @@ xref: spec_2_position "Protein N-term"
 xref: spec_2_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "S"
+xref: spec_3_site "T"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "T"
+xref: spec_3_site "S"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
@@ -41374,7 +41383,7 @@ xref: delta_composition "H(14) C(9) N(2) O(4)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2017-08-18 09:43:05"
-xref: date_time_modified "2024-01-26 11:17:27"
+xref: date_time_modified "2024-08-12 10:23:14"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -41388,12 +41397,12 @@ xref: spec_2_position "Protein N-term"
 xref: spec_2_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "S"
+xref: spec_3_site "T"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "T"
+xref: spec_3_site "S"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
@@ -41415,7 +41424,7 @@ xref: delta_composition "H(23) C(13) N(3) O(6)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2017-08-18 09:44:40"
-xref: date_time_modified "2024-01-26 11:18:42"
+xref: date_time_modified "2024-08-12 10:22:49"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -41429,12 +41438,12 @@ xref: spec_2_position "Protein N-term"
 xref: spec_2_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "S"
+xref: spec_3_site "T"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "T"
+xref: spec_3_site "S"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
@@ -41535,7 +41544,7 @@ xref: delta_composition "H(12) C(9) N(2) O(3)"
 xref: username_of_poster "unimod"
 xref: group_of_poster ""
 xref: date_time_posted "2017-08-31 14:57:02"
-xref: date_time_modified "2024-01-26 11:15:23"
+xref: date_time_modified "2024-08-12 10:22:34"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -41549,12 +41558,12 @@ xref: spec_2_position "Protein N-term"
 xref: spec_2_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "S"
+xref: spec_3_site "T"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
 xref: spec_3_hidden "1"
-xref: spec_3_site "T"
+xref: spec_3_site "S"
 xref: spec_3_position "Anywhere"
 xref: spec_3_classification "Chemical derivative"
 xref: spec_3_group "3"
@@ -42043,7 +42052,7 @@ xref: delta_composition "H(10) C(17) O(6)"
 xref: username_of_poster "shenmic"
 xref: group_of_poster ""
 xref: date_time_posted "2017-10-17 14:58:16"
-xref: date_time_modified "2017-11-02 17:07:54"
+xref: date_time_modified "2024-08-12 09:57:33"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -45466,8 +45475,8 @@ is_a: UNIMOD:0 ! unimod root node
 
 [Term]
 id: UNIMOD:2067
-name: Mono_Nγ-propargyl-L-Gln_desthiobiotin
-def: "Monomodification of Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2067]
+name: Mono_Ngamma-propargyl-L-Gln_desthiobiotin
+def: "Monomodification of Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2067]
 comment: - desthiobiotin-azide to enrich L-Gln-propargyl modified peptides.
 synonym: "Enrichment of modified peptides using desthiobiotin-tag on streptavidin beads" RELATED []
 xref: record_id "2067"
@@ -45477,7 +45486,7 @@ xref: delta_composition "H(44) C(26) N(8) O(8)"
 xref: username_of_poster "KielkowskiLab"
 xref: group_of_poster ""
 xref: date_time_posted "2022-08-05 13:31:40"
-xref: date_time_modified "2023-02-01 15:18:52"
+xref: date_time_modified "2024-08-12 11:07:02"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -45489,8 +45498,8 @@ is_a: UNIMOD:0 ! unimod root node
 
 [Term]
 id: UNIMOD:2068
-name: Di_L-Glu_Nγ-propargyl-L-Gln_desthiobiotin
-def: "Dimodification of L-Glu and Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2068]
+name: Di_L-Glu_Ngamma-propargyl-L-Gln_desthiobiotin
+def: "Dimodification of L-Glu and Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2068]
 comment: - desthiobiotin-azide to enrich L-Gln-propargyl modified peptides.
 xref: record_id "2068"
 xref: delta_mono_mass "709.375889"
@@ -45499,17 +45508,13 @@ xref: delta_composition "H(51) C(31) N(9) O(10)"
 xref: username_of_poster "KielkowskiLab"
 xref: group_of_poster ""
 xref: date_time_posted "2022-08-09 13:38:45"
-xref: date_time_modified "2022-10-20 14:03:23"
+xref: date_time_modified "2024-08-12 11:06:43"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
 xref: spec_1_site "D"
 xref: spec_1_position "Anywhere"
 xref: spec_1_classification "Chemical derivative"
-xref: spec_1_neutral_loss_470_mono_mass "469.301268"
-xref: spec_1_neutral_loss_470_avge_mass "469.5783"
-xref: spec_1_neutral_loss_470_flag "false"
-xref: spec_1_neutral_loss_470_composition "H(39) C(21) N(7) O(5)"
 xref: spec_1_neutral_loss_197_mono_mass "196.121178"
 xref: spec_1_neutral_loss_197_avge_mass "196.2462"
 xref: spec_1_neutral_loss_197_flag "false"
@@ -45518,11 +45523,19 @@ xref: spec_1_neutral_loss_728_mono_mass "727.386454"
 xref: spec_1_neutral_loss_728_avge_mass "727.8062"
 xref: spec_1_neutral_loss_728_flag "false"
 xref: spec_1_neutral_loss_728_composition "H(53) C(31) N(9) O(11)"
+xref: spec_1_neutral_loss_470_mono_mass "469.301268"
+xref: spec_1_neutral_loss_470_avge_mass "469.5783"
+xref: spec_1_neutral_loss_470_flag "false"
+xref: spec_1_neutral_loss_470_composition "H(39) C(21) N(7) O(5)"
 xref: spec_2_group "2"
 xref: spec_2_hidden "1"
 xref: spec_2_site "E"
 xref: spec_2_position "Anywhere"
 xref: spec_2_classification "Chemical derivative"
+xref: spec_2_neutral_loss_197_mono_mass "196.121178"
+xref: spec_2_neutral_loss_197_avge_mass "196.2462"
+xref: spec_2_neutral_loss_197_flag "false"
+xref: spec_2_neutral_loss_197_composition "H(16) C(10) N(2) O(2)"
 xref: spec_2_neutral_loss_470_mono_mass "469.301268"
 xref: spec_2_neutral_loss_470_avge_mass "469.5783"
 xref: spec_2_neutral_loss_470_flag "false"
@@ -45531,17 +45544,13 @@ xref: spec_2_neutral_loss_728_mono_mass "727.386454"
 xref: spec_2_neutral_loss_728_avge_mass "727.8062"
 xref: spec_2_neutral_loss_728_flag "false"
 xref: spec_2_neutral_loss_728_composition "H(53) C(31) N(9) O(11)"
-xref: spec_2_neutral_loss_197_mono_mass "196.121178"
-xref: spec_2_neutral_loss_197_avge_mass "196.2462"
-xref: spec_2_neutral_loss_197_flag "false"
-xref: spec_2_neutral_loss_197_composition "H(16) C(10) N(2) O(2)"
 is_a: UNIMOD:0 ! unimod root node
 
 
 [Term]
 id: UNIMOD:2069
-name: Di_L-Gln_Nγ-propargyl-L-Gln_desthiobiotin
-def: "Dimodification of L-Gln and Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2069]
+name: Di_L-Gln_Ngamma-propargyl-L-Gln_desthiobiotin
+def: "Dimodification of L-Gln and Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2069]
 comment: - desthiobiotin-azide to enrich L-Gln-propargyl modified peptides.
 xref: record_id "2069"
 xref: delta_mono_mass "708.391873"
@@ -45550,13 +45559,17 @@ xref: delta_composition "H(52) C(31) N(10) O(9)"
 xref: username_of_poster "KielkowskiLab"
 xref: group_of_poster ""
 xref: date_time_posted "2022-08-09 13:45:33"
-xref: date_time_modified "2022-10-20 14:03:49"
+xref: date_time_modified "2024-08-12 11:06:19"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
 xref: spec_1_site "D"
 xref: spec_1_position "Anywhere"
 xref: spec_1_classification "Chemical derivative"
+xref: spec_1_neutral_loss_197_mono_mass "196.121178"
+xref: spec_1_neutral_loss_197_avge_mass "196.2462"
+xref: spec_1_neutral_loss_197_flag "false"
+xref: spec_1_neutral_loss_197_composition "H(16) C(10) N(2) O(2)"
 xref: spec_1_neutral_loss_727_mono_mass "726.402438"
 xref: spec_1_neutral_loss_727_avge_mass "726.8215"
 xref: spec_1_neutral_loss_727_flag "false"
@@ -45565,10 +45578,6 @@ xref: spec_1_neutral_loss_470_mono_mass "469.301268"
 xref: spec_1_neutral_loss_470_avge_mass "469.5783"
 xref: spec_1_neutral_loss_470_flag "false"
 xref: spec_1_neutral_loss_470_composition "H(39) C(21) N(7) O(5)"
-xref: spec_1_neutral_loss_197_mono_mass "196.121178"
-xref: spec_1_neutral_loss_197_avge_mass "196.2462"
-xref: spec_1_neutral_loss_197_flag "false"
-xref: spec_1_neutral_loss_197_composition "H(16) C(10) N(2) O(2)"
 xref: spec_2_group "2"
 xref: spec_2_hidden "1"
 xref: spec_2_site "E"
@@ -45726,7 +45735,7 @@ xref: delta_composition "H C(6) N(3) O(3)"
 xref: username_of_poster "thibautvignane"
 xref: group_of_poster ""
 xref: date_time_posted "2023-03-30 16:05:51"
-xref: date_time_modified "2023-10-05 14:37:58"
+xref: date_time_modified "2024-08-12 10:35:44"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -45750,7 +45759,7 @@ is_a: UNIMOD:0 ! unimod root node
 id: UNIMOD:2080
 name: DCP
 def: "Dimedone-Based Chemical Probes." [PMID:20513473, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2080]
-synonym: "Use for enrichment of cysteine oxidation Cleaved Cysteine Sulfenic Acid Probe (DCP-Bio1)" RELATED []
+synonym: "Cleaved Cysteine Sulfenic Acid Probe (DCP-Bio1) Use for enrichment of cysteine oxidation" RELATED []
 xref: record_id "2080"
 xref: delta_mono_mass "168.078644"
 xref: delta_avge_mass "168.1898"
@@ -45758,7 +45767,7 @@ xref: delta_composition "H(12) C(9) O(3)"
 xref: username_of_poster "thibautvignane"
 xref: group_of_poster ""
 xref: date_time_posted "2023-04-19 18:49:30"
-xref: date_time_modified "2023-10-05 14:37:23"
+xref: date_time_modified "2024-08-12 10:35:12"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -45885,7 +45894,7 @@ xref: delta_composition "H(11) C(6) N O"
 xref: username_of_poster "dzolg"
 xref: group_of_poster ""
 xref: date_time_posted "2023-12-04 11:10:14"
-xref: date_time_modified "2024-02-29 10:48:20"
+xref: date_time_modified "2024-07-08 16:54:51"
 xref: approved "0"
 xref: spec_1_group "1"
 xref: spec_1_hidden "1"
@@ -45916,3 +45925,407 @@ xref: spec_1_classification "Isotopic label"
 is_a: UNIMOD:0 ! unimod root node
 
 
+[Term]
+id: UNIMOD:2106
+name: DPIA
+def: "Desthiobiotinylation of cysteine with DPIA (Desthiobiotin polyethyleneoxide iodoacetamide) probe." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2106]
+xref: record_id "2106"
+xref: delta_mono_mass "455.274384"
+xref: delta_avge_mass "455.5484"
+xref: delta_composition "H(37) C(21) N(5) O(6)"
+xref: username_of_poster "bdwyer"
+xref: group_of_poster ""
+xref: date_time_posted "2024-04-22 22:51:46"
+xref: date_time_modified "2024-04-22 22:51:46"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "C"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Chemical derivative"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2107
+name: Acetoacetyl
+def: "Acetoacetylation." [URL:https\://www.genome.jp/entry/C00332, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2107]
+xref: record_id "2107"
+xref: delta_mono_mass "84.021129"
+xref: delta_avge_mass "84.0734"
+xref: delta_composition "H(4) C(4) O(2)"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-22 12:17:22"
+xref: date_time_modified "2024-07-05 12:18:20"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2108
+name: Isovaleryl
+def: "Isovalerylation." [URL:https\://www.genome.jp/entry/C02939, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2108]
+xref: record_id "2108"
+xref: delta_mono_mass "84.057515"
+xref: delta_avge_mass "84.1164"
+xref: delta_composition "H(8) C(5) O"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-22 12:24:23"
+xref: date_time_modified "2024-06-28 10:55:54"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2109
+name: 2-methylbutyryl
+def: "2-methylbutyrylation." [URL:https\://www.kegg.jp/entry/C01033, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2109]
+xref: record_id "2109"
+xref: delta_mono_mass "84.057515"
+xref: delta_avge_mass "84.1164"
+xref: delta_composition "H(8) C(5) O"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-22 12:30:37"
+xref: date_time_modified "2024-06-28 10:57:45"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2110
+name: Tiglyl
+def: "Tiglylation." [URL:https\://www.genome.jp/entry/C03345, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2110]
+xref: record_id "2110"
+xref: delta_mono_mass "82.041865"
+xref: delta_avge_mass "82.1005"
+xref: delta_composition "H(6) C(5) O"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-22 12:33:24"
+xref: date_time_modified "2024-07-05 12:15:40"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2111
+name: 3-methylglutaryl
+def: "3-methylglutarylation." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2111]
+xref: record_id "2111"
+xref: delta_mono_mass "128.047344"
+xref: delta_avge_mass "128.1259"
+xref: delta_composition "H(8) C(6) O(3)"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-22 14:19:16"
+xref: date_time_modified "2024-06-22 14:19:16"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2112
+name: 3-methylglutaconyl
+def: "3-methylglutaconylation." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2112]
+xref: record_id "2112"
+xref: delta_mono_mass "126.031694"
+xref: delta_avge_mass "126.11"
+xref: delta_composition "H(6) C(6) O(3)"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-22 14:21:47"
+xref: date_time_modified "2024-06-22 14:21:47"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2113
+name: 3-hydroxy-3-methylglutaryl
+def: "3-hydroxy-3-methylglutarylation." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2113]
+xref: record_id "2113"
+xref: delta_mono_mass "144.042259"
+xref: delta_avge_mass "144.1253"
+xref: delta_composition "H(8) C(6) O(4)"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-22 14:24:06"
+xref: date_time_modified "2024-06-22 14:24:06"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2114
+name: Lactylation
+def: "Lactylation(Lac)." [PMID:31645732, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2114]
+xref: record_id "2114"
+xref: delta_mono_mass "72.021129"
+xref: delta_avge_mass "72.0627"
+xref: delta_composition "H(4) C(3) O(2)"
+xref: username_of_poster "cpu1107"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-24 10:56:15"
+xref: date_time_modified "2024-08-09 09:54:27"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2115
+name: Pyruvoyl
+def: "Pyruvoylation." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2115]
+xref: record_id "2115"
+xref: delta_mono_mass "70.005479"
+xref: delta_avge_mass "70.0468"
+xref: delta_composition "H(2) C(3) O(2)"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-24 18:33:34"
+xref: date_time_modified "2024-08-09 09:54:42"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2116
+name: Glyoxylyl
+def: "Glyoxylylation." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2116]
+xref: record_id "2116"
+xref: delta_mono_mass "55.989829"
+xref: delta_avge_mass "56.0202"
+xref: delta_composition "C(2) O(2)"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-24 19:20:20"
+xref: date_time_modified "2024-08-09 09:54:55"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2117
+name: Itaconatyl
+def: "Itaconatylation." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2117]
+xref: record_id "2117"
+xref: delta_mono_mass "130.026609"
+xref: delta_avge_mass "130.0987"
+xref: delta_composition "H(6) C(5) O(4)"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-24 20:02:30"
+xref: date_time_modified "2024-08-09 09:55:04"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "C"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2118
+name: Itaconyl
+def: "Itaconylation." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2118]
+xref: record_id "2118"
+xref: delta_mono_mass "112.016044"
+xref: delta_avge_mass "112.0835"
+xref: delta_composition "H(4) C(5) O(3)"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-26 14:01:07"
+xref: date_time_modified "2024-08-09 09:55:19"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2119
+name: ValGly
+def: "UFMylation residue." [PMID:8383789, PMID:33066455, PMID:http://www.ncbi.nlm.nih.gov/pubmed/35756382, PMID:35756382, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2119]
+comment: The valine glycine residues left on ufmylated lysine after tryptic digestion.
+synonym: "UFMylation leaving VG tag valineglycine" RELATED []
+xref: record_id "2119"
+xref: delta_mono_mass "156.089878"
+xref: delta_avge_mass "156.1824"
+xref: delta_composition "H(12) C(7) N(2) O(2)"
+xref: username_of_poster "pscaturro"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-26 14:09:36"
+xref: date_time_modified "2024-06-26 14:09:36"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2120
+name: Pentanoyl
+def: "Pentanoylation." [URL:https\://www.genome.jp/entry/C00888, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2120]
+synonym: "Valeryl" RELATED []
+xref: record_id "2120"
+xref: delta_mono_mass "84.057515"
+xref: delta_avge_mass "84.1164"
+xref: delta_composition "H(8) C(5) O"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-26 14:12:23"
+xref: date_time_modified "2024-06-28 10:53:01"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2121
+name: Hexanoyl
+def: "Hexanoylation." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2121]
+xref: record_id "2121"
+xref: delta_mono_mass "98.073165"
+xref: delta_avge_mass "98.143"
+xref: delta_composition "H(10) C(6) O"
+xref: username_of_poster "JakobB"
+xref: group_of_poster ""
+xref: date_time_posted "2024-06-26 14:24:17"
+xref: date_time_modified "2024-06-26 14:24:17"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Post-translational"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2122
+name: Label:13C(6)15N(2)+TMT6plex
+def: "Sixplex Tandem Mass Tag 13C(6) 15N(2) Silac label." [PMID:34847359, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2122]
+comment: Tandem Mass Tag and TMT are registered Trademarks of Proteome Sciences plc.
+xref: record_id "2122"
+xref: delta_mono_mass "237.177131"
+xref: delta_avge_mass "237.2062"
+xref: delta_composition "H(20) C(2) 13C(10) N(-1) 15N(3) O(2)"
+xref: username_of_poster "dzolg"
+xref: group_of_poster ""
+xref: date_time_posted "2024-07-01 12:49:15"
+xref: date_time_modified "2024-08-12 11:33:03"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Multiple"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2123
+name: Label:13C(6)15N(2)+TMTpro
+def: "TMTpro Tandem Mass Tag 13C(6) 15N(2) Silac label." [PMID:34847359, UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2123]
+comment: Tandem Mass Tag and TMT are registered Trademarks of Proteome Sciences plc.
+xref: record_id "2123"
+xref: delta_mono_mass "312.221344"
+xref: delta_avge_mass "312.2554"
+xref: delta_composition "H(25) C(2) 13C(13) N(-1) 15N(4) O(3)"
+xref: username_of_poster "dzolg"
+xref: group_of_poster ""
+xref: date_time_posted "2024-07-01 12:51:56"
+xref: date_time_modified "2024-08-12 11:33:20"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "K"
+xref: spec_1_position "Anywhere"
+xref: spec_1_classification "Multiple"
+is_a: UNIMOD:0 ! unimod root node
+
+
+[Term]
+id: UNIMOD:2126
+name: 2PCA-triazole-ethanethiol
+def: "Cleaved 2PCA clicked to biotin-SS-azide." [UNIMODURL:http\://www.unimod.org/modifications_view.php?editid1=2126]
+xref: record_id "2126"
+xref: delta_mono_mass "216.046967"
+xref: delta_avge_mass "216.2623"
+xref: delta_composition "H(8) C(10) N(4) S"
+xref: username_of_poster "pscaturro"
+xref: group_of_poster ""
+xref: date_time_posted "2024-07-08 10:09:29"
+xref: date_time_modified "2024-08-09 09:56:09"
+xref: approved "0"
+xref: spec_1_group "1"
+xref: spec_1_hidden "1"
+xref: spec_1_site "N-term"
+xref: spec_1_position "Any N-term"
+xref: spec_1_classification "Other"
+is_a: UNIMOD:0 ! unimod root node
+
+
diff --git a/pwiz/data/msdata/ReaderTest.cpp b/pwiz/data/msdata/ReaderTest.cpp
index e0fdcc7316..e15fba145b 100755
--- a/pwiz/data/msdata/ReaderTest.cpp
+++ b/pwiz/data/msdata/ReaderTest.cpp
@@ -263,9 +263,7 @@ void testIdentifyFileFormat()
         set<string> readerTypeSet(readerTypes.begin(), readerTypes.end());
         set<string> expectedTypeSet{ "mzML", "mzMLb", "mzXML", "MS1", "MS2", "Mascot Generic", "Bruker Data Exchange", "MZ5",
                                      "Sciex WIFF", "Sciex WIFF2", "AB/Sciex T2D", "Agilent MassHunter", "Bruker FID", "Bruker YEP", "Bruker BAF", "Bruker U2", "Bruker TDF", "Bruker TSF",
-#if defined(PWIZ_READER_MOBILION)
                                      "Mobilion MBI",
-#endif
                                      "Shimadzu LCD", "Thermo RAW", "UIMF", "Waters RAW", "Waters UNIFI" };
         auto expectedButNotFound = expectedTypeSet - readerTypeSet;
         auto foundButNotExpected = readerTypeSet - expectedTypeSet;
@@ -279,7 +277,7 @@ void testIdentifyFileFormat()
         auto readerTypes = readerList.getCvTypes();
         set<CVID> readerCvTypeSet(readerTypes.begin(), readerTypes.end());
         set<CVID> expectedCvTypeSet{ MS_mzML_format, MS_ISB_mzXML_format, MS_MS1_format, MS_MS2_format, MS_Mascot_MGF_format, MS_Bruker_XML_format, MS_mz5_format,
-                                     MS_mzMLb_format, MS_ABI_WIFF_format, MS_SCIEX_TOF_TOF_T2D_format, MS_Agilent_MassHunter_format,
+                                     MS_mzMLb_format, MS_ABI_WIFF_format, MS_SCIEX_TOF_TOF_T2D_format, MS_Agilent_MassHunter_format, MS_Mobilion_MBI_format,
                                      MS_Bruker_FID_format, MS_Bruker_Agilent_YEP_format, MS_Bruker_BAF_format, MS_Bruker_U2_format, MS_Bruker_TDF_format, MS_Bruker_TSF_format,
                                      MS_mass_spectrometer_file_format, MS_Thermo_RAW_format, MS_UIMF_format, MS_Waters_raw_format };
         auto expectedButNotFound = expectedCvTypeSet - readerCvTypeSet;
@@ -297,10 +295,8 @@ void testIdentifyFileFormat()
     unit_assert_operator_equal(2, extByType["Bruker YEP"].size());
     unit_assert_operator_equal(".d", extByType["Bruker YEP"][0]);
     unit_assert_operator_equal(".yep", extByType["Bruker YEP"][1]);
-#if defined(PWIZ_READER_MOBILION)
     unit_assert_operator_equal(1, extByType["Mobilion MBI"].size());
     unit_assert_operator_equal(".mbi", extByType["Mobilion MBI"][0]);
-#endif
 }
 
 
diff --git a/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion.cpp b/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion.cpp
index 99ce9f98b4..24e81d0b91 100644
--- a/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion.cpp
+++ b/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion.cpp
@@ -82,7 +82,7 @@ void fillInMetadata(const string& rawpath, MBIFile* rawdata, MSData& msd)
 
     bool hasMS1 = false, hasMS2 = false;
     for (size_t i = 1; i <= rawdata->NumFrames() && (!hasMS1 || !hasMS2); ++i)
-        if (rawdata->GetFrame(i)->isFragmentationData())
+        if (rawdata->GetFrame(i)->GetCE(0) > 0)
             hasMS2 = true;
         else
             hasMS1 = true;
@@ -100,8 +100,8 @@ void fillInMetadata(const string& rawpath, MBIFile* rawdata, MSData& msd)
     sourceFile->id = BFS_STRING(sourcePath.leaf());
     sourceFile->name = BFS_STRING(sourcePath.leaf());
     sourceFile->location = "file:///" + BFS_GENERIC_STRING(BFS_COMPLETE(sourcePath.branch_path()));
-    sourceFile->set(MS_Bruker_TDF_nativeID_format);
-    sourceFile->set(MS_file_format);
+    sourceFile->set(MS_Mobilion_MBI_nativeID_format);
+    sourceFile->set(MS_Mobilion_MBI_format);
     msd.fileDescription.sourceFilePtrs.push_back(sourceFile);
 
     msd.id = bfs::basename(sourcePath);
diff --git a/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/2024-02-16-16.02.20-CCS Calibration_02-combineIMS.mzML b/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/2024-02-16-16.02.20-CCS Calibration_02-combineIMS.mzML
index 9d4fac16ee..a7dc5bfc83 100644
--- a/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/2024-02-16-16.02.20-CCS Calibration_02-combineIMS.mzML	
+++ b/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/2024-02-16-16.02.20-CCS Calibration_02-combineIMS.mzML	
@@ -1,7 +1,7 @@
 <?xml version="1.0" encoding="utf-8"?>
 <mzML xmlns="http://psi.hupo.org/ms/mzml" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/ms/mzml http://psidev.info/files/ms/mzML/xsd/mzML1.1.0.xsd" id="2024-02-16-16.02.20-CCS Calibration_02" version="1.1.0">
   <cvList count="2">
-    <cv id="MS" fullName="Proteomics Standards Initiative Mass Spectrometry Ontology" version="4.1.136" URI="https://raw.githubusercontent.com/HUPO-PSI/psi-ms-CV/master/psi-ms.obo"/>
+    <cv id="MS" fullName="Proteomics Standards Initiative Mass Spectrometry Ontology" version="4.1.182" URI="https://raw.githubusercontent.com/HUPO-PSI/psi-ms-CV/master/psi-ms.obo"/>
     <cv id="UO" fullName="Unit Ontology" version="09:04:2014" URI="https://raw.githubusercontent.com/bio-ontology-research-group/unit-ontology/master/unit.obo"/>
   </cvList>
   <fileDescription>
@@ -12,8 +12,8 @@
     </fileContent>
     <sourceFileList count="1">
       <sourceFile id="_x0032_024-02-16-16.02.20-CCS_x0020_Calibration_02.mbi" name="2024-02-16-16.02.20-CCS Calibration_02.mbi" location="file:///C:/dev/pwiz-mbi/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data">
-        <cvParam cvRef="MS" accession="MS:1002818" name="Bruker TDF nativeID format" value=""/>
-        <cvParam cvRef="MS" accession="MS:1001459" name="file format" value=""/>
+        <cvParam cvRef="MS" accession="MS:1001186" name="Mobilion MBI nativeID format" value=""/>
+        <cvParam cvRef="MS" accession="MS:1001185" name="Mobilion MBI format" value=""/>
         <cvParam cvRef="MS" accession="MS:1000569" name="SHA-1" value="a89249901325977e5464ed1d9d6a92fa0a32cde1"/>
       </sourceFile>
     </sourceFileList>
@@ -22,7 +22,7 @@
     <software id="MOBILion" version="Ozone-v1.0.12.0">
       <cvParam cvRef="MS" accession="MS:1001455" name="acquisition software" value=""/>
     </software>
-    <software id="pwiz_Reader_Mobilion" version="3.0.24282">
+    <software id="pwiz_Reader_Mobilion" version="3.0.24295">
       <cvParam cvRef="MS" accession="MS:1000615" name="ProteoWizard software" value=""/>
     </software>
   </softwareList>
diff --git a/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/2024-02-16-16.02.20-CCS Calibration_02.mzML b/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/2024-02-16-16.02.20-CCS Calibration_02.mzML
index be4630a9cd..7ab6dd9f71 100644
--- a/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/2024-02-16-16.02.20-CCS Calibration_02.mzML	
+++ b/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/2024-02-16-16.02.20-CCS Calibration_02.mzML	
@@ -1,7 +1,7 @@
 <?xml version="1.0" encoding="utf-8"?>
 <mzML xmlns="http://psi.hupo.org/ms/mzml" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/ms/mzml http://psidev.info/files/ms/mzML/xsd/mzML1.1.0.xsd" id="2024-02-16-16.02.20-CCS Calibration_02" version="1.1.0">
   <cvList count="2">
-    <cv id="MS" fullName="Proteomics Standards Initiative Mass Spectrometry Ontology" version="4.1.136" URI="https://raw.githubusercontent.com/HUPO-PSI/psi-ms-CV/master/psi-ms.obo"/>
+    <cv id="MS" fullName="Proteomics Standards Initiative Mass Spectrometry Ontology" version="4.1.182" URI="https://raw.githubusercontent.com/HUPO-PSI/psi-ms-CV/master/psi-ms.obo"/>
     <cv id="UO" fullName="Unit Ontology" version="09:04:2014" URI="https://raw.githubusercontent.com/bio-ontology-research-group/unit-ontology/master/unit.obo"/>
   </cvList>
   <fileDescription>
@@ -12,8 +12,8 @@
     </fileContent>
     <sourceFileList count="1">
       <sourceFile id="_x0032_024-02-16-16.02.20-CCS_x0020_Calibration_02.mbi" name="2024-02-16-16.02.20-CCS Calibration_02.mbi" location="file:///C:/dev/pwiz-mbi/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data">
-        <cvParam cvRef="MS" accession="MS:1002818" name="Bruker TDF nativeID format" value=""/>
-        <cvParam cvRef="MS" accession="MS:1001459" name="file format" value=""/>
+        <cvParam cvRef="MS" accession="MS:1001186" name="Mobilion MBI nativeID format" value=""/>
+        <cvParam cvRef="MS" accession="MS:1001185" name="Mobilion MBI format" value=""/>
         <cvParam cvRef="MS" accession="MS:1000569" name="SHA-1" value="a89249901325977e5464ed1d9d6a92fa0a32cde1"/>
       </sourceFile>
     </sourceFileList>
@@ -22,7 +22,7 @@
     <software id="MOBILion" version="Ozone-v1.0.12.0">
       <cvParam cvRef="MS" accession="MS:1001455" name="acquisition software" value=""/>
     </software>
-    <software id="pwiz_Reader_Mobilion" version="3.0.24282">
+    <software id="pwiz_Reader_Mobilion" version="3.0.24295">
       <cvParam cvRef="MS" accession="MS:1000615" name="ProteoWizard software" value=""/>
     </software>
   </softwareList>
diff --git a/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/ExampleTuneMix_binned5-combineIMS.mzML b/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/ExampleTuneMix_binned5-combineIMS.mzML
index 2daa7eebca..5cca1a6d09 100644
--- a/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/ExampleTuneMix_binned5-combineIMS.mzML
+++ b/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/ExampleTuneMix_binned5-combineIMS.mzML
@@ -1,7 +1,7 @@
 <?xml version="1.0" encoding="utf-8"?>
 <mzML xmlns="http://psi.hupo.org/ms/mzml" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/ms/mzml http://psidev.info/files/ms/mzML/xsd/mzML1.1.0.xsd" id="ExampleTuneMix_binned5" version="1.1.0">
   <cvList count="2">
-    <cv id="MS" fullName="Proteomics Standards Initiative Mass Spectrometry Ontology" version="4.1.136" URI="https://raw.githubusercontent.com/HUPO-PSI/psi-ms-CV/master/psi-ms.obo"/>
+    <cv id="MS" fullName="Proteomics Standards Initiative Mass Spectrometry Ontology" version="4.1.182" URI="https://raw.githubusercontent.com/HUPO-PSI/psi-ms-CV/master/psi-ms.obo"/>
     <cv id="UO" fullName="Unit Ontology" version="09:04:2014" URI="https://raw.githubusercontent.com/bio-ontology-research-group/unit-ontology/master/unit.obo"/>
   </cvList>
   <fileDescription>
@@ -11,9 +11,9 @@
       <cvParam cvRef="MS" accession="MS:1000235" name="total ion current chromatogram" value=""/>
     </fileContent>
     <sourceFileList count="1">
-      <sourceFile id="ExampleTuneMix_binned5.mbi" name="ExampleTuneMix_binned5.mbi" location="file:///C:/dev/pwiz/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data">
-        <cvParam cvRef="MS" accession="MS:1002818" name="Bruker TDF nativeID format" value=""/>
-        <cvParam cvRef="MS" accession="MS:1001459" name="file format" value=""/>
+      <sourceFile id="ExampleTuneMix_binned5.mbi" name="ExampleTuneMix_binned5.mbi" location="file:///C:/dev/pwiz-mbi/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data">
+        <cvParam cvRef="MS" accession="MS:1001186" name="Mobilion MBI nativeID format" value=""/>
+        <cvParam cvRef="MS" accession="MS:1001185" name="Mobilion MBI format" value=""/>
         <cvParam cvRef="MS" accession="MS:1000569" name="SHA-1" value="e98237a4afdb7d202cbe608d4ceab4d7ddd832e5"/>
       </sourceFile>
     </sourceFileList>
@@ -22,7 +22,7 @@
     <software id="MOBILion" version="123.456.78">
       <cvParam cvRef="MS" accession="MS:1001455" name="acquisition software" value=""/>
     </software>
-    <software id="pwiz_Reader_Mobilion" version="3.0.24184">
+    <software id="pwiz_Reader_Mobilion" version="3.0.24295">
       <cvParam cvRef="MS" accession="MS:1000615" name="ProteoWizard software" value=""/>
     </software>
   </softwareList>
diff --git a/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/ExampleTuneMix_binned5.mzML b/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/ExampleTuneMix_binned5.mzML
index 09d9b9122f..e492f917ba 100644
--- a/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/ExampleTuneMix_binned5.mzML
+++ b/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data/ExampleTuneMix_binned5.mzML
@@ -1,7 +1,7 @@
 <?xml version="1.0" encoding="utf-8"?>
 <mzML xmlns="http://psi.hupo.org/ms/mzml" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/ms/mzml http://psidev.info/files/ms/mzML/xsd/mzML1.1.0.xsd" id="ExampleTuneMix_binned5" version="1.1.0">
   <cvList count="2">
-    <cv id="MS" fullName="Proteomics Standards Initiative Mass Spectrometry Ontology" version="4.1.136" URI="https://raw.githubusercontent.com/HUPO-PSI/psi-ms-CV/master/psi-ms.obo"/>
+    <cv id="MS" fullName="Proteomics Standards Initiative Mass Spectrometry Ontology" version="4.1.182" URI="https://raw.githubusercontent.com/HUPO-PSI/psi-ms-CV/master/psi-ms.obo"/>
     <cv id="UO" fullName="Unit Ontology" version="09:04:2014" URI="https://raw.githubusercontent.com/bio-ontology-research-group/unit-ontology/master/unit.obo"/>
   </cvList>
   <fileDescription>
@@ -11,9 +11,9 @@
       <cvParam cvRef="MS" accession="MS:1000235" name="total ion current chromatogram" value=""/>
     </fileContent>
     <sourceFileList count="1">
-      <sourceFile id="ExampleTuneMix_binned5.mbi" name="ExampleTuneMix_binned5.mbi" location="file:///C:/dev/pwiz/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data">
-        <cvParam cvRef="MS" accession="MS:1002818" name="Bruker TDF nativeID format" value=""/>
-        <cvParam cvRef="MS" accession="MS:1001459" name="file format" value=""/>
+      <sourceFile id="ExampleTuneMix_binned5.mbi" name="ExampleTuneMix_binned5.mbi" location="file:///C:/dev/pwiz-mbi/pwiz/data/vendor_readers/Mobilion/Reader_Mobilion_Test.data">
+        <cvParam cvRef="MS" accession="MS:1001186" name="Mobilion MBI nativeID format" value=""/>
+        <cvParam cvRef="MS" accession="MS:1001185" name="Mobilion MBI format" value=""/>
         <cvParam cvRef="MS" accession="MS:1000569" name="SHA-1" value="e98237a4afdb7d202cbe608d4ceab4d7ddd832e5"/>
       </sourceFile>
     </sourceFileList>
@@ -22,7 +22,7 @@
     <software id="MOBILion" version="123.456.78">
       <cvParam cvRef="MS" accession="MS:1001455" name="acquisition software" value=""/>
     </software>
-    <software id="pwiz_Reader_Mobilion" version="3.0.24184">
+    <software id="pwiz_Reader_Mobilion" version="3.0.24295">
       <cvParam cvRef="MS" accession="MS:1000615" name="ProteoWizard software" value=""/>
     </software>
   </softwareList>
diff --git a/pwiz/utility/bindings/CLI/common/cv.hpp b/pwiz/utility/bindings/CLI/common/cv.hpp
index 8b1da3c8d6..fa791d9a4b 100644
--- a/pwiz/utility/bindings/CLI/common/cv.hpp
+++ b/pwiz/utility/bindings/CLI/common/cv.hpp
@@ -38,8 +38,8 @@
 
 // ["psi-ms.obo"]
 //   format-version: 1.2
-//   data-version: 4.1.163
-//   date: 19:07:2024 07:15
+//   data-version: 4.1.182
+//   date: 11:10:2024 07:15
 //   saved-by: Joshua Klein
 //   auto-generated-by: OBO-Edit 2.3.1
 //   default-namespace: MS
@@ -59,7 +59,7 @@
 //   remark: creator: Gerhard Mayer <mayerg97 <-at-> rub.de>
 //   remark: creator: Joshua Klein <jaklein <-at-> bu.edu>
 //   remark: creator: Chris Bielow <chris.bielow <-at-> fu-berlin.de>
-//   remark: creator: Wout Bittremieux <wbittremieux <-at-> health.ucsd.edu>
+//   remark: creator: Wout Bittremieux <wout.bittremieux <-at-> uantwerpen.be>
 //   remark: creator: Nils Hoffmann < nils.hoffmann <-at-> cebitec.uni-bielefeld.de>
 //   remark: creator: Julian Uszkoreit <julian.uszkoreit <-at-> ruhr-uni-bochum.de>
 //   remark: creator: Mathias Walzer <walzer <-at-> ebi.ac.uk>
@@ -73,7 +73,7 @@
 //
 // ["unimod.obo"]
 //   format-version: 1.4
-//   date: 29:02:2024 10:49
+//   date: 12:08:2024 11:33
 //
 // ["unit.obo"]
 //   format-version: 1.2
@@ -3892,8 +3892,11 @@ public enum class CVID
     /// <summary>single protein identification statistic: Results specific for one protein as part of a protein ambiguity group (a result not valid for all the other proteins in the protein ambiguity group).</summary>
     MS_single_protein_identification_statistic = 1001116,
 
+    /// <summary>theoretical neutral mass: The theoretical neutral mass of the molecule (e.g. the peptide sequence and its modifications) not including its charge carrier.</summary>
+    MS_theoretical_neutral_mass = 1001117,
+
     /// <summary>theoretical mass: The theoretical neutral mass of the molecule (e.g. the peptide sequence and its modifications) not including its charge carrier.</summary>
-    MS_theoretical_mass = 1001117,
+    MS_theoretical_mass = MS_theoretical_neutral_mass,
 
     /// <summary>param: b ion: Parameter information, type of product: b ion with charge on the N-terminal side.</summary>
     MS_param__b_ion = 1001118,
@@ -4084,6 +4087,12 @@ public enum class CVID
     /// <summary>search statistics: The details of the actual run of the search.</summary>
     MS_search_statistics = 1001184,
 
+    /// <summary>Mobilion MBI format: Mobilion MBI file format.</summary>
+    MS_Mobilion_MBI_format = 1001185,
+
+    /// <summary>Mobilion MBI nativeID format: Native format defined by frame=xsd:nonNegativeInteger scan=xsd:nonNegativeInteger.</summary>
+    MS_Mobilion_MBI_nativeID_format = 1001186,
+
     /// <summary>modification specificity peptide N-term: As parameter for search engine: apply the modification only at the N-terminus of a peptide.</summary>
     MS_modification_specificity_peptide_N_term = 1001189,
 
@@ -7564,8 +7573,11 @@ public enum class CVID
     /// <summary>second-pass peptide identification: A putative identified peptide found in a second-pass search of protein sequences selected from a first-pass search.</summary>
     MS_second_pass_peptide_identification = 1002341,
 
+    /// <summary>mzmine: A framework for differential analysis of mass spectrometry data.</summary>
+    MS_mzmine = 1002342,
+
     /// <summary>MZmine: A framework for differential analysis of mass spectrometry data.</summary>
-    MS_MZmine = 1002342,
+    MS_MZmine = MS_mzmine,
 
     /// <summary>ion stability type: Stability type of the ion.</summary>
     MS_ion_stability_type_OBSOLETE = 1002343,
@@ -10849,6 +10861,48 @@ public enum class CVID
     /// <summary>electron beam energy: The kinetic energy of the electron beam used in dissociation methods induced by a free electron beam, such as electron-capture dissociation (ECD), electron-detachment dissociation (EDD), and electron-activated dissociation (EAD).</summary>
     MS_electron_beam_energy = 1003410,
 
+    /// <summary>Orbitrap IQ-X: Thermo Scientific Orbitrap IQ-X mass spectrometer with Tribrid architecture consisting of quadrupole mass filter, linear ion trap and Orbitrap mass analyzers.</summary>
+    MS_Orbitrap_IQ_X = 1003411,
+
+    /// <summary>timsTOF Ultra 2: Bruker Daltonics timsTOF Ultra 2.</summary>
+    MS_timsTOF_Ultra_2 = 1003412,
+
+    /// <summary>Kojak: Kojak open-source crosslinked peptide sequence search engine developed at the Institute for Systems Biology.</summary>
+    MS_Kojak = 1003413,
+
+    /// <summary>Kojak:score: The Kojak score for an individual peptide sequence, similar to Comet:xcorr.</summary>
+    MS_Kojak_score = 1003414,
+
+    /// <summary>Kojak:expectation value: The Kojak expectation value for an individual peptide sequence.</summary>
+    MS_Kojak_expectation_value = 1003415,
+
+    /// <summary>Kojak:matched ions: The number of matched ions for an individual peptide sequence in a Kojak result.</summary>
+    MS_Kojak_matched_ions = 1003416,
+
+    /// <summary>Kojak:consecutive matched ions: The highest run of consecutive matched ions for an individual peptide sequence in a Kojak result.</summary>
+    MS_Kojak_consecutive_matched_ions = 1003417,
+
+    /// <summary>Kojak:delta score: The difference between the top Kojak score and the next best Kojak score for a PSM.</summary>
+    MS_Kojak_delta_score = 1003418,
+
+    /// <summary>Kojak:rank: The rank of an individual peptide from the first pass of the Kojak scoring algorithm. Applies only to sequences in a crosslinked result.</summary>
+    MS_Kojak_rank = 1003419,
+
+    /// <summary>Kojak:score xlink: The Kojak score for a crosslinked pair of peptide sequences, similar to Comet:xcorr.</summary>
+    MS_Kojak_score_xlink = 1003420,
+
+    /// <summary>Kojak:expectation value xlink: The Kojak expectation value for a crosslinked pair of peptide sequences.</summary>
+    MS_Kojak_expectation_value_xlink = 1003421,
+
+    /// <summary>Kojak:matched ions xlink: The number of matched ions for a crosslinked pair of peptide sequences in a Kojak result.</summary>
+    MS_Kojak_matched_ions_xlink = 1003422,
+
+    /// <summary>Orbitrap Exploris GC 240: Orbitrap Exploris GC 240 Mass Spectrometer.</summary>
+    MS_Orbitrap_Exploris_GC_240 = 1003423,
+
+    /// <summary>selected fragment theoretical m/z observed intensity spectrum: Spectrum for which the peaks are limited to a subset of known product ions that are important for subsequent identification, whose m/z values are corrected to theoretical values, and intensity values are experimentally derived.</summary>
+    MS_selected_fragment_theoretical_m_z_observed_intensity_spectrum = 1003424,
+
     /// <summary>Number of Occurrences: The number of times something happened.</summary>
     NCIT_Number_of_Occurrences = 103150827,
 
@@ -10924,6 +10978,30 @@ public enum class CVID
     /// <summary>environment metric: QC metric related to measurements of the ambient environment, such as the laboratory.</summary>
     MS_environment_metric = 4000024,
 
+    /// <summary>precursor ion current chromatogram: Representation of the ion current assigned to detected precursors in the series of all MS1 spectra versus time.</summary>
+    MS_precursor_ion_current_chromatogram = 4000025,
+
+    /// <summary>precursor ion chromatogram: Representation of the ion current assigned to detected precursors in the series of all MS1 spectra versus time.</summary>
+    MS_precursor_ion_chromatogram = MS_precursor_ion_current_chromatogram,
+
+    /// <summary>fragment ppm deviation median: The median of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied.</summary>
+    MS_fragment_ppm_deviation_median = 4000026,
+
+    /// <summary>fragment ppm deviation mean: The mean of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied</summary>
+    MS_fragment_ppm_deviation_mean = 4000027,
+
+    /// <summary>fragment ppm deviation sigma: The standard deviation of the distribution of observed fragment mass accuracies (MS:4000072) [in ppm] of identified MS2 spectra after user-defined acceptance criteria (FDR) are applied</summary>
+    MS_fragment_ppm_deviation_sigma = 4000028,
+
+    /// <summary>area under TIC in MS1: The area under the total ion current chromatogram (MS:1000235) of all MS1 spectra.</summary>
+    MS_area_under_TIC_in_MS1 = 4000029,
+
+    /// <summary>area under TIC in MS2: The area under the total ion current chromatogram (MS:1000235) of all MS2 spectra.</summary>
+    MS_area_under_TIC_in_MS2 = 4000030,
+
+    /// <summary>peak area of MS1 vs MS2 signal ratio: The ratio of the area under TIC of MS1 (MS:4000029) divided by the area under the TIC of MS2 (MS:4000030).</summary>
+    MS_peak_area_of_MS1_vs_MS2_signal_ratio = 4000031,
+
     /// <summary>XIC50 fraction: The number of XIC that account for the top half of all XIC-FWHM divided by the number of all XIC.</summary>
     MS_XIC50_fraction = 4000050,
 
@@ -15883,14 +15961,14 @@ public enum class CVID
     /// <summary>DBIA: Desthiobiotinylation of cysteine with DBIA probe.</summary>
     UNIMOD_DBIA = 300002062,
 
-    /// <summary>Mono_Nγ-propargyl-L-Gln_desthiobiotin: Monomodification of Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide.</summary>
-    UNIMOD_Mono_N___propargyl_L_Gln_desthiobiotin = 300002067,
+    /// <summary>Mono_Ngamma-propargyl-L-Gln_desthiobiotin: Monomodification of Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide.</summary>
+    UNIMOD_Mono_Ngamma_propargyl_L_Gln_desthiobiotin = 300002067,
 
-    /// <summary>Di_L-Glu_Nγ-propargyl-L-Gln_desthiobiotin: Dimodification of L-Glu and Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide.</summary>
-    UNIMOD_Di_L_Glu_N___propargyl_L_Gln_desthiobiotin = 300002068,
+    /// <summary>Di_L-Glu_Ngamma-propargyl-L-Gln_desthiobiotin: Dimodification of L-Glu and Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide.</summary>
+    UNIMOD_Di_L_Glu_Ngamma_propargyl_L_Gln_desthiobiotin = 300002068,
 
-    /// <summary>Di_L-Gln_Nγ-propargyl-L-Gln_desthiobiotin: Dimodification of L-Gln and Nγ-propargyl-L-Gln probe with clicked desthiobiotin-azide.</summary>
-    UNIMOD_Di_L_Gln_N___propargyl_L_Gln_desthiobiotin = 300002069,
+    /// <summary>Di_L-Gln_Ngamma-propargyl-L-Gln_desthiobiotin: Dimodification of L-Gln and Ngamma-propargyl-L-Gln probe with clicked desthiobiotin-azide.</summary>
+    UNIMOD_Di_L_Gln_Ngamma_propargyl_L_Gln_desthiobiotin = 300002069,
 
     /// <summary>L-Gln: Monomodification with glutamine.</summary>
     UNIMOD_L_Gln = 300002070,
@@ -15931,6 +16009,63 @@ public enum class CVID
     /// <summary>Label:13C(2)15N(1): 13C(2) 15N(1) Silac label.</summary>
     UNIMOD_Label_13C_2_15N_1_ = 300002088,
 
+    /// <summary>DPIA: Desthiobiotinylation of cysteine with DPIA (Desthiobiotin polyethyleneoxide iodoacetamide) probe.</summary>
+    UNIMOD_DPIA = 300002106,
+
+    /// <summary>Acetoacetyl: Acetoacetylation.</summary>
+    UNIMOD_Acetoacetyl = 300002107,
+
+    /// <summary>Isovaleryl: Isovalerylation.</summary>
+    UNIMOD_Isovaleryl = 300002108,
+
+    /// <summary>2-methylbutyryl: 2-methylbutyrylation.</summary>
+    UNIMOD_2_methylbutyryl = 300002109,
+
+    /// <summary>Tiglyl: Tiglylation.</summary>
+    UNIMOD_Tiglyl = 300002110,
+
+    /// <summary>3-methylglutaryl: 3-methylglutarylation.</summary>
+    UNIMOD_3_methylglutaryl = 300002111,
+
+    /// <summary>3-methylglutaconyl: 3-methylglutaconylation.</summary>
+    UNIMOD_3_methylglutaconyl = 300002112,
+
+    /// <summary>3-hydroxy-3-methylglutaryl: 3-hydroxy-3-methylglutarylation.</summary>
+    UNIMOD_3_hydroxy_3_methylglutaryl = 300002113,
+
+    /// <summary>Lactylation: Lactylation(Lac).</summary>
+    UNIMOD_Lactylation = 300002114,
+
+    /// <summary>Pyruvoyl: Pyruvoylation.</summary>
+    UNIMOD_Pyruvoyl = 300002115,
+
+    /// <summary>Glyoxylyl: Glyoxylylation.</summary>
+    UNIMOD_Glyoxylyl = 300002116,
+
+    /// <summary>Itaconatyl: Itaconatylation.</summary>
+    UNIMOD_Itaconatyl = 300002117,
+
+    /// <summary>Itaconyl: Itaconylation.</summary>
+    UNIMOD_Itaconyl = 300002118,
+
+    /// <summary>ValGly: UFMylation residue.</summary>
+    UNIMOD_ValGly = 300002119,
+
+    /// <summary>Pentanoyl: Pentanoylation.</summary>
+    UNIMOD_Pentanoyl = 300002120,
+
+    /// <summary>Hexanoyl: Hexanoylation.</summary>
+    UNIMOD_Hexanoyl = 300002121,
+
+    /// <summary>Label:13C(6)15N(2)+TMT6plex: Sixplex Tandem Mass Tag 13C(6) 15N(2) Silac label.</summary>
+    UNIMOD_Label_13C_6_15N_2__TMT6plex = 300002122,
+
+    /// <summary>Label:13C(6)15N(2)+TMTpro: TMTpro Tandem Mass Tag 13C(6) 15N(2) Silac label.</summary>
+    UNIMOD_Label_13C_6_15N_2__TMTpro = 300002123,
+
+    /// <summary>2PCA-triazole-ethanethiol: Cleaved 2PCA clicked to biotin-SS-azide.</summary>
+    UNIMOD_2PCA_triazole_ethanethiol = 300002126,
+
     /// <summary>unit: A unit of measurement is a standardized quantity of a physical quality.</summary>
     UO_unit = 400000000,