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Dear Dev-Team, |
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Replies: 3 comments
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Soon we will have more information about the tables on the website, because we are still working on their content, we decided to wait a little bit more. Can you tell me what's the version you are running and what kind of data base you have ? |
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@prvst Right now i am using the HEK Data: For a better understanding: Thanks for your efforts! |
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Proteins are inferred and grouped according to the logic implemented in ProteinProphet, you might want to check some of Alexey's papers describing how the program works [1] [2]. If you feel comfortable, you might also take a look at your protXML file, there you will observe how the protein groups were formed and organized. Since we are not the official maintainers of ProteinProphet, I'm not planning to add any documentation on how the software works, sorry for that. Regarding the results you see there; The indistinguishable list represents only proteins that cannot be differentiated between each other, that's why you don't see many of them. This is specially common if you are using a database like RefSeq or Swiss-Prot. If you add isoforms or variants to it, then you will see more cases like this. It is also important to note that this is different from proteins that share peptides because of a common region. Please feel free to reopen the issue if you still have other concerns or questions. |
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Proteins are inferred and grouped according to the logic implemented in ProteinProphet, you might want to check some of Alexey's papers describing how the program works [1] [2]. If you feel comfortable, you might also take a look at your protXML file, there you will observe how the protein groups were formed and organized. Since we are not the official maintainers of ProteinProphet, I'm not planning to add any documentation on how the software works, sorry for that.
Regarding the results you see there; The indistinguishable list represents only proteins that cannot be differentiated between each other, that's why you don't see many of them. This is specially common if you are using a data…