diff --git a/{{cookiecutter.project_name}}/Modules/Scripted/Home/Home.py b/{{cookiecutter.project_name}}/Modules/Scripted/Home/Home.py
index 7b79a70..d409a90 100644
--- a/{{cookiecutter.project_name}}/Modules/Scripted/Home/Home.py
+++ b/{{cookiecutter.project_name}}/Modules/Scripted/Home/Home.py
@@ -46,6 +46,8 @@ def toolbarNames(self) -> list[str]:
 
     _toolbars: Mapping[str, qt.QToolBar] = {}
 
+    _slicerDefaultPalette: Optional[qt.QPalette] = None
+
     def __init__(self, parent: Optional[qt.QWidget]):
         """Called when the application opens the module the first time and the widget is initialized."""
         ScriptedLoadableModuleWidget.__init__(self, parent)
@@ -70,6 +72,8 @@ def setup(self):
         # See https://github.com/KitwareMedical/SlicerCustomAppTemplate/issues/72
         self.uiWidget.setPalette(slicer.util.mainWindow().style().standardPalette())
 
+        self._slicerDefaultPalette = slicer.app.palette()
+
         # Remove unneeded UI elements
         self.modifyWindowUI()
         self.setCustomUIVisible(True)
@@ -134,7 +138,10 @@ def toggleStyle(self, visible: bool):
         if visible:
             self.applyApplicationStyle()
         else:
+            # Modern Qt controls use Qt Stylesheets (.qss) to control dynamic styling
             slicer.app.styleSheet = ""
+            # Legacy Qt-derived controls (see CTK controls) use Qt palettes for styling
+            slicer.app.setPalette(self._slicerDefaultPalette)
 
     def raiseSettings(self, _):
         self.settingsDialog.exec()
@@ -144,9 +151,20 @@ def setCustomUIVisible(self, visible: bool):
 
     def applyApplicationStyle(self):
         SlicerCustomAppUtilities.applyStyle([slicer.app], self.resourcePath("Home.qss"))
+        self.applyApplicationPalette()
         self.styleThreeDWidget()
         self.styleSliceWidgets()
 
+    def applyApplicationPalette(self):
+        """Apply custom palette colors to the application as a workaround for restyling
+        custom CTK and qMRML controls that do not yet respect Qt stylesheets.
+        """
+        highlightColor = qt.QColor("#009D49")  # Kitware - Green
+
+        p = self._slicerDefaultPalette
+        p.setColor(qt.QPalette.Highlight, highlightColor)
+        slicer.app.setPalette(p)
+
     def styleThreeDWidget(self):
         viewNode = slicer.app.layoutManager().threeDWidget(0).mrmlViewNode()  # noqa: F841
         # viewNode.SetBackgroundColor(0.0, 0.0, 0.0)