Alternate methods of normalisation

[melaniemccoy]

Hi Tom,

In the intro to the Spectre batch alignment workflow, you state that if you 'do not have reference controls processed with each batch, then other forms of batch alignment might be possible – see our data integration options for more information'. Could you point me in the direction of this info as I can't seem to find it anywhere? I'm trying to analyse data acquired across 14 experiments. We did run a reference control (i.e. sample taken from the same donor) in each experiment, but these were from three separate blood draws. I'm therefore wondering if I can use a combination of Cytonorm + alternate method of normalisation... Any thoughts / advice much appreciated.

Many thanks
Mel