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CONFIGURATION ERROR: Reference genome mismatch: #222

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HyojeenLee opened this issue Dec 2, 2022 · 0 comments
Open

CONFIGURATION ERROR: Reference genome mismatch: #222

HyojeenLee opened this issue Dec 2, 2022 · 0 comments

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@HyojeenLee
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Hellp, I got an error like below.

CONFIGURATION ERROR:
Reference genome mismatch: Reference fasta file is missing a chromosome found in the normal BAM/CRAM file: 'chr11_KI270721v1_random'.

I used in aligning, an indexed version of reference genome (hg39.fa to) hg38.mmi (which was suggested by minimap2 to reduce time),
then should I use the same hg38.mmi or hg38.fa for the reference in Strelka configuration?

Thank you

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