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about us

About us

This is the website for the Ishaque-Lab, supervised by Naveed Ishaque who is the group leader for Computational Oncology at the Center of Digital Healthhttps://www.bihealth.org/en/research/research-group/eils-lab-bih-digital-health-center at the Berlin Insitute of Health at Charite University Hospitalhttps://www.bihealth.org.

Our group's interest lies in understanding the basis of biological heterogeneity using computational approaches applied to 'omics data in a disease context. We employ artificial intelligence (AI) and data science (DS) methods, not only to address the underlying causes of this heterogeneity but also the interactions between different molecular ‘omics layers. We have a strong specialization in the application area of oncology but are also very interested in immunology and neurodegenerative diseases.

By better understanding global and local patterns in biological data, we believe we can better differentiate the mechanisms behind biological and molecular processes from technical noise. As such, we rely on establishing close ties with experimental collaborators who can provide us with large-scale and high-dimensional datasets profiled using state-of-the-art and exotic 'omics profiling techniques. We aim to take advantage of recent technological advances that can resolve single-cell, spatial, temporal, and genetic heterogeneity.

Lab members

Member Position
Dr. Naveed Ishaque Group leader
Franziska Mueller Project manager
Dr Sebastian Mackowiak Senior bioinformatician
Dr Johanna Denkena Post doctoral researcher
Olivia Debnath PhD student
Shashwat Sahay PhD student
Sebastian Tiesmeyer PhD student
Alexander Malt PhD student
Niklas Mueller-Boetticher PhD student
Runbing Han PhD student
Yiheng Jiang PhD student
Jakub Otreba (FU Berlin) Masters student
Shudi Xu (FU Berlin) Masters student