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DESCRIPTION
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DESCRIPTION
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Package: CATALYST
Type: Package
Title: Cytometry dATa anALYSis Tools
Version: 1.29.2
Depends: R (>= 4.4), SingleCellExperiment
Authors@R: c(
person("Helena L.", "Crowell",
role=c("aut", "cre"),
email="[email protected]",
comment=c(ORCID="0000-0002-4801-1767")),
person("Vito R.T.", "Zanotelli", role="aut",
comment=c(ORCID="0000-0001-7268-311X")),
person("Stéphane", "Chevrier", role=c("aut", "dtc"),
comment=c(ORCID="0000-0002-9216-7910")),
person("Mark D.", "Robinson", role=c("aut", "fnd"),
comment=c(ORCID="0000-0002-3048-5518")),
person("Bernd", "Bodenmiller", role="fnd",
comment=c(ORCID="0000-0002-6325-7861")))
biocViews:
Clustering, DataImport, DifferentialExpression, ExperimentalDesign,
FlowCytometry, ImmunoOncology, MassSpectrometry,Normalization,
Preprocessing, SingleCell, Software, StatisticalMethod, Visualization
Description:
CATALYST provides tools for preprocessing of and differential discovery
in cytometry data such as FACS, CyTOF, and IMC. Preprocessing includes
i) normalization using bead standards, ii) single-cell deconvolution,
and iii) bead-based compensation.
For differential discovery, the package provides a number of convenient
functions for data processing (e.g., clustering, dimension reduction),
as well as a suite of visualizations for exploratory data analysis and
exploration of results from differential abundance (DA) and state (DS)
analysis in order to identify differences in composition and expression
profiles at the subpopulation-level, respectively.
Imports:
circlize, ComplexHeatmap, ConsensusClusterPlus, cowplot,
data.table, dplyr, drc,
flowCore, FlowSOM,
ggplot2, ggrepel, ggridges, graphics, grDevices, grid, gridExtra,
Matrix, matrixStats, methods,
nnls,
purrr,
RColorBrewer, reshape2, Rtsne,
SummarizedExperiment,
S4Vectors, scales, scater, stats
Suggests:
BiocStyle, diffcyt, flowWorkspace, ggcyto,
knitr, openCyto, rmarkdown, testthat, uwot
URL: https://github.com/HelenaLC/CATALYST
BugReports: https://github.com/HelenaLC/CATALYST/issues
VignetteBuilder: knitr
RoxygenNote: 7.3.1
License: GPL (>=2)
Encoding: UTF-8
LazyData: true