Description

A simple script that takes a list of UniProt IDs, and pulls residue-level annotations from UniProt using the ID mapping tool via the public API.

As of now, it produces a .csv file with the following info:

• UniProt ID
• Residue ID
• Residue features (e.g. 'Natural variant', 'Modified residue' etc.)
• Curated variants (from humsavar)
• Subcellular locations
• GO terms (all and categorised)

Getting Started

The program takes as input a list of UniProt IDs and outputs a .csv file with the annotated residues.

Dependencies

No dependencies for now - only a modern version of Python (>=3.10).

Installing

No installation needed, just clone the repo and it should be ready to run.

Executing program

• Given that you have a list of UniProt IDs, you can run with something like:

python uniprot_annotation.py -i ids.list -o output.csv 

Help

For usage help run:

python uniprot_annotation.py -h

Authors

Ioannis Riziotis