diff --git a/src/components/ButtonWithDropdownMenu/index.tsx b/src/components/ButtonWithDropdownMenu/index.tsx
index 1fa40ad1b6f..1eeadde84c4 100644
--- a/src/components/ButtonWithDropdownMenu/index.tsx
+++ b/src/components/ButtonWithDropdownMenu/index.tsx
@@ -5,10 +5,12 @@ import Button from '@components/Button';
 import Icon from '@components/Icon';
 import * as Expensicons from '@components/Icon/Expensicons';
 import PopoverMenu from '@components/PopoverMenu';
+import useKeyboardShortcut from '@hooks/useKeyboardShortcut';
 import useStyleUtils from '@hooks/useStyleUtils';
 import useTheme from '@hooks/useTheme';
 import useThemeStyles from '@hooks/useThemeStyles';
 import useWindowDimensions from '@hooks/useWindowDimensions';
+import mergeRefs from '@libs/mergeRefs';
 import * as Modal from '@userActions/Modal';
 import CONST from '@src/CONST';
 import type {AnchorPosition} from '@src/styles';
@@ -37,6 +39,7 @@ function ButtonWithDropdownMenu<IValueType>({
     onOptionsMenuHide,
     enterKeyEventListenerPriority = 0,
     wrapperStyle,
+    useKeyboardShortcuts = false,
 }: ButtonWithDropdownMenuProps<IValueType>) {
     const theme = useTheme();
     const styles = useThemeStyles();
@@ -46,6 +49,7 @@ function ButtonWithDropdownMenu<IValueType>({
     const [popoverAnchorPosition, setPopoverAnchorPosition] = useState<AnchorPosition | null>(null);
     const {windowWidth, windowHeight} = useWindowDimensions();
     const dropdownAnchor = useRef<View | null>(null);
+    const dropdownButtonRef = isSplitButton ? buttonRef : mergeRefs(buttonRef, dropdownAnchor);
     const selectedItem = options[selectedItemIndex] || options[0];
     const innerStyleDropButton = StyleUtils.getDropDownButtonHeight(buttonSize);
     const isButtonSizeLarge = buttonSize === CONST.DROPDOWN_BUTTON_SIZE.LARGE;
@@ -70,6 +74,19 @@ function ButtonWithDropdownMenu<IValueType>({
             });
         }
     }, [windowWidth, windowHeight, isMenuVisible, anchorAlignment.vertical]);
+
+    useKeyboardShortcut(
+        CONST.KEYBOARD_SHORTCUTS.CTRL_ENTER,
+        (e) => {
+            onPress(e, selectedItem.value);
+        },
+        {
+            captureOnInputs: true,
+            shouldBubble: false,
+            isActive: useKeyboardShortcuts,
+        },
+    );
+
     return (
         <View style={wrapperStyle}>
             {shouldAlwaysShowDropdownMenu || options.length > 1 ? (
@@ -77,12 +94,7 @@ function ButtonWithDropdownMenu<IValueType>({
                     <Button
                         success={success}
                         pressOnEnter={pressOnEnter}
-                        ref={(ref) => {
-                            if (isSplitButton) {
-                                return;
-                            }
-                            dropdownAnchor.current = ref;
-                        }}
+                        ref={dropdownButtonRef}
                         onPress={(event) => (!isSplitButton ? setIsMenuVisible(!isMenuVisible) : onPress(event, selectedItem.value))}
                         text={customText ?? selectedItem.text}
                         isDisabled={isDisabled || !!selectedItem?.disabled}
diff --git a/src/components/ButtonWithDropdownMenu/types.ts b/src/components/ButtonWithDropdownMenu/types.ts
index f20729380b6..e4b81da9494 100644
--- a/src/components/ButtonWithDropdownMenu/types.ts
+++ b/src/components/ButtonWithDropdownMenu/types.ts
@@ -90,6 +90,9 @@ type ButtonWithDropdownMenuProps<TValueType> = {
 
     /** Whether the button should use split style or not */
     isSplitButton?: boolean;
+
+    /** Whether to use keyboard shortcuts for confirmation or not */
+    useKeyboardShortcuts?: boolean;
 };
 
 export type {
diff --git a/src/components/MoneyRequestConfirmationList.tsx b/src/components/MoneyRequestConfirmationList.tsx
index c0aaaa08d0a..8ab996dcbfe 100755
--- a/src/components/MoneyRequestConfirmationList.tsx
+++ b/src/components/MoneyRequestConfirmationList.tsx
@@ -805,6 +805,7 @@ function MoneyRequestConfirmationList({
                     vertical: CONST.MODAL.ANCHOR_ORIGIN_VERTICAL.BOTTOM,
                 }}
                 enterKeyEventListenerPriority={1}
+                useKeyboardShortcuts
             />
         ) : (
             <ButtonWithDropdownMenu
@@ -815,6 +816,7 @@ function MoneyRequestConfirmationList({
                 options={splitOrRequestOptions}
                 buttonSize={CONST.DROPDOWN_BUTTON_SIZE.LARGE}
                 enterKeyEventListenerPriority={1}
+                useKeyboardShortcuts
             />
         );
 
@@ -910,6 +912,7 @@ function MoneyRequestConfirmationList({
                 listFooterContent={listFooterContent}
                 containerStyle={[styles.flexBasisAuto]}
                 removeClippedSubviews={false}
+                disableKeyboardShortcuts
             />
         </MouseProvider>
     );
diff --git a/src/components/SettlementButton.tsx b/src/components/SettlementButton.tsx
index 5c984af94d1..efe7aa91de1 100644
--- a/src/components/SettlementButton.tsx
+++ b/src/components/SettlementButton.tsx
@@ -113,6 +113,9 @@ type SettlementButtonProps = SettlementButtonOnyxProps & {
 
     /** Callback to open confirmation modal if any of the transactions is on HOLD */
     confirmApproval?: () => void;
+
+    /** Whether to use keyboard shortcuts for confirmation or not */
+    useKeyboardShortcuts?: boolean;
 };
 
 function SettlementButton({
@@ -148,6 +151,7 @@ function SettlementButton({
     enterKeyEventListenerPriority = 0,
     confirmApproval,
     policy,
+    useKeyboardShortcuts = false,
     onPaymentOptionsShow,
     onPaymentOptionsHide,
 }: SettlementButtonProps) {
@@ -322,6 +326,7 @@ function SettlementButton({
                     buttonSize={buttonSize}
                     anchorAlignment={paymentMethodDropdownAnchorAlignment}
                     enterKeyEventListenerPriority={enterKeyEventListenerPriority}
+                    useKeyboardShortcuts={useKeyboardShortcuts}
                 />
             )}
         </KYCWall>