diff --git a/src/ontology/efo-edit.owl b/src/ontology/efo-edit.owl
index 18d1ad1e..55f7ea87 100644
--- a/src/ontology/efo-edit.owl
+++ b/src/ontology/efo-edit.owl
@@ -16995,6 +16995,8 @@ Declaration(Class(efo:EFO_0022608))
 Declaration(Class(efo:EFO_0022609))
 Declaration(Class(efo:EFO_0022610))
 Declaration(Class(efo:EFO_0022611))
+Declaration(Class(efo:EFO_0022612))
+Declaration(Class(efo:EFO_0022613))
 Declaration(Class(efo:EFO_0030000))
 Declaration(Class(efo:EFO_0030001))
 Declaration(Class(efo:EFO_0030002))
@@ -204459,6 +204461,24 @@ AnnotationAssertion(oboInOwl:hasExactSynonym efo:EFO_0022611 "cardiac MRI")
 AnnotationAssertion(rdfs:label efo:EFO_0022611 "magnetic resonance imaging of the heart"@en)
 SubClassOf(efo:EFO_0022611 efo:EFO_0004311)
 
+# Class: efo:EFO_0022612 (complicated appendicitis)
+
+AnnotationAssertion(obo:IAO_0000115 efo:EFO_0022612 "Appendicitis characterised by the presence of complications such as localised abscess, peritonitis and perforation.")
+AnnotationAssertion(dc:creator efo:EFO_0022612 "Zoe May Pendlington")
+AnnotationAssertion(dc:date efo:EFO_0022612 "2024-06-06T09:37:06Z"^^xsd:dateTime)
+AnnotationAssertion(oboInOwl:hasDbXref efo:EFO_0022612 "SNOMEDCT:418171008")
+AnnotationAssertion(rdfs:label efo:EFO_0022612 "complicated appendicitis"@en)
+SubClassOf(efo:EFO_0022612 efo:EFO_0007149)
+
+# Class: efo:EFO_0022613 (gangrenous appendicits)
+
+AnnotationAssertion(obo:IAO_0000115 efo:EFO_0022613 "Appendicitis classified as gangrenous due to the presence of necrosis, based on histological examination.")
+AnnotationAssertion(dc:creator efo:EFO_0022613 "Zoe May Pendlington")
+AnnotationAssertion(dc:date efo:EFO_0022613 "2024-06-06T09:39:30Z"^^xsd:dateTime)
+AnnotationAssertion(oboInOwl:hasDbXref efo:EFO_0022613 "SNOMEDCT:50846009")
+AnnotationAssertion(rdfs:label efo:EFO_0022613 "gangrenous appendicits"@en)
+SubClassOf(efo:EFO_0022613 efo:EFO_0007149)
+
 # Class: efo:EFO_0030000 (STARmap)
 
 AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29930089") Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-3090-9894") obo:IAO_0000115 efo:EFO_0030000 "STARmap is an image-based technology for 3D intact-tissue RNA sequencing, which integrates hydrogel-tissue chemistry, targeted signal amplification, and in situ sequencing.")