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Temporal viral dynamic #50

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chapuisk opened this issue Sep 27, 2021 · 0 comments
Open

Temporal viral dynamic #50

chapuisk opened this issue Sep 27, 2021 · 0 comments
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enhancement New feature or request epidemiology Anything related to the epidemiological part of the model

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@chapuisk
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Is your feature request related to a problem? Please describe.
For now when an individual enter a state, it acquire all variables value that change once, and nothing (or so) is modified since another state shift happen. For instance when someone enter latent phase, viral load should increase slowly until a threshold is met, triggering state change (in this case becoming infectious); the same way when one enter infectious phase, viral load should quickly shift to its maximum and then decline/explode/etc.

Describe the solution you'd like
Explicitly represent the disease states with viral load temporal dynamic, hence making it possible to anchor test results, state shift and infectiousness on dynamic variable, rather than the state per se

Describe alternatives you've considered
Having various random value to represent heterogeneity between states (more viral load during infectious state) and individuals (more viral load for super spreaders)

Additional context
When considering test failure and, in particular, false negatives, the timing of the test, that should reflect in very contrasting viral load, is quite important !

@chapuisk chapuisk self-assigned this Sep 27, 2021
@chapuisk chapuisk added enhancement New feature or request epidemiology Anything related to the epidemiological part of the model labels Sep 27, 2021
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Labels
enhancement New feature or request epidemiology Anything related to the epidemiological part of the model
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