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Drug Class Breakdown for Different Databases

ARO

Counts
Total descendants 602
Direct descendants 61
Intermediate nodes 33
Leaves 508

Other databases

ARG-ANNOT

Original ID count
bla 1479
agly 193
mls 101
gly 88
flq 74
col 65
tet 60
phe 59
tmt 47
fcyn 30
oxzln 19
rif 9
ntmdz 7
fcd 5
sul 4
fus 1
agly_flqn 1
mupirocin 1
tetracenomycinc 1

Number of unique antibiotic classes: 19

DeepARG

Original ID count
multidrug 4454
beta-lactam 2878
mls 1710
tetracycline 557
fosfomycin 434
aminoglycoside 403
glycopeptide 349
unclassified 313
bacitracin 280
polymyxin 245
fluoroquinolone 159
phenicol 155
sulfonamide 125
diaminopyrimidine 87
rifamycin 40
fosmidomycin 28
peptide 23
tetracenomycin_c 8
nucleoside 6
fusidic-acid 6
triclosan 4
aminocoumarin 3
fusaric-acid 2
antibacterial_free_fatty_acids 2
mupirocin 1
aminoglycoside:aminocoumarin 1
polyamine:peptide 1
acridine_dye 1
pleuromutilin 1
bicyclomycin 1
oxazolidinone 1
nitroimidazole 1

Number of unique antibiotic classes: 32

MEGARes

Original ID count
betalactams 4599
aminoglycosides 800
fluoroquinolones 319
tetracyclines 301
glycopeptides 300
mls 297
drug_and_biocide_resistance 189
phenicol 150
trimethoprim 147
multi-drug_resistance 130
lipopeptides 109
sulfonamides 105
rifampin 74
fosfomycin 70
aminocoumarins 41
mycobacterium_tuberculosis-specific_drug 32
elfamycins 22
metronidazole 21
nucleosides 15
cationic_antimicrobial_peptides 13
fusidic_acid 11
bacitracin 6
drug_and_biocide_and_metal_resistance 6
mupirocin 5
multi-metal_resistance 5
oxazolidinone 4
phenolic_compound_resistance 4
mercury_resistance 4
pleuromutilin 4
thiopeptides 2
tellurium_resistance 2
spiropyrimidinetriones 1
tetracenomycin 1
pactamycin 1
biocide_and_metal_resistance 1
copper_resistance 1
aldehyde_resistance 1

Number of unique antibiotic classes: 37

NCBI

Original ID count
beta-lactam 4579
1026
aminoglycoside 695
tetracycline 241
glycopeptide 236
quinolone 139
phenicol 131
trimethoprim 127
colistin 116
stx2 113
macrolide 81
lincosamide/macrolide/streptogramin 80
efflux 71
fosfomycin 64
arsenic 52
mercury 48
phenicol/quinolone 43
intimin 43
sulfonamide 41
quaternary_ammonium 40
lincosamide 37
copper 26
rifamycin 21
stx1 20
streptogramin 19
lincosamide/macrolide 17
streptothricin 14
macrolide/streptogramin 13
nickel 12
nitroimidazole 10
aminoglycoside/quinolone 10
lincosamide/streptogramin 10
bleomycin 10
phenicol/lincosamide/oxazolidinone/pleuromutilin/streptogramin 9
tellurium 9
copper/silver 8
cadmium 7
lincosamide/pleuromutilin/streptogramin 7
fusidic_acid 7
phenicol/oxazolidinone 4
pleuromutilin 4
mupirocin 3
bacitracin 3
copper/nickel 2
thiostrepton 2
chromate 2
cadmium/cobalt/nickel 2
ionophore 2
silver 2
tuberactinomycin 2
macrolide/phenicol 1
cadmium/lead/zinc 1
tetracenomycin 1
fluoroquinolone 1
lincosamide/pleuromutilin 1
avilamycin 1
gold 1
copper/gold 1
aminoglycoside/phenicol 1
fluoride 1

Number of unique antibiotic classes: 60

SARG

Type count
beta_lactam 4579
multidrug 3388
macrolide-lincosamide-streptogramin 1765
fosfomycin 454
aminoglycoside 406
tetracycline 388
quinolone 337
polymyxin 327
bacitracin 294
vancomycin 201
sulfonamide 133
trimethoprim 122
chloramphenicol 117
novobiocin 94
florfenicol 37
rifamycin 28
other_peptide_antibiotics 15
bleomycin 11
fusidic_acid 10
tetracenomycin_C 8
streptothricin 7
pleuromutilin_tiamulin 5
defensin 5
tunicamycin 4
puromycin 3
mupirocin 3
antibacterial_fatty_acid 2
bicyclomycin 1
factumycin 1
edeine 1

Number of unique antibiotic classes: 30

ResFinder

Class count
Beta-lactam 2016
Aminoglycoside 261
Folate pathway antagonist 163
Tetracycline 161
Quinolone 126
Polymyxin 106
Macrolide, Lincosamide, Streptogramin B 80
Glycopeptide 46
Fosfomycin 42
Amphenicol 41
Macrolide 39
Oxazolidinone, Amphenicol 20
Nitroimidazole 14
Streptogramin A 14
Lincosamide, Streptogramin A, Pleuromutilin 13
Lincosamide 12
Rifamycin 10
Oxazolidinone, Amphenicol, Lincosamide, Streptogramin A, Pleuromutilin 7
Macrolide, Streptogramin B 7
Aminoglycoside, Quinolone 3
Steroid antibacterial 3
Pseudomonic acid 3
Lincosamide, Streptogramin A 3
Amphenicol, Oxazolidinone, Tetracycline 2
Streptogramin B 2
Amphenicol, Quinolone, Folate pathway antagonist 2
Ionophores 2
Pleuromutilin 1
Macrolide, Tetracycline 1
Streptogramin A, Streptogramin B 1
Macrolide, Lincosamide, Streptogramin A, Streptogramin B, Tetracycline 1
Macrolide, Lincosamide 1

Number of unique antibiotic classes: 32

ResFinderFG

1 count
TMP 1670
CYC 1403
TET 833
SXT 643
PEN 538
AMX 535
CHL 475
PIP 292
CAZ 251
AMP 241
GEN 175
ATM 163
TGC 156
FOX 74
CTX 57
CAR 55
AMC 54
TZP 52
KAN 45
FEP 33
CST 21
SPT 12
OXY 11
MIN 11
bLac 9
CDR 9
SIS 9
ERY 8
CEF 6
AZM 5
SMZ 5
TET/AMP 4
STX 4
SDX 4
MEM 3
STG 2
AMK 2
TYL 1
CIP 1
APR 1
STR 1
TZB 1

Number of unique antibiotic classes: 42