diff --git a/5.2-Module5_genenmania_web_lab.Rmd b/5.2-Module5_genenmania_web_lab.Rmd index f6ed184..e69ac70 100644 --- a/5.2-Module5_genenmania_web_lab.Rmd +++ b/5.2-Module5_genenmania_web_lab.Rmd @@ -138,7 +138,7 @@ The top functions predicted by GeneMANIA for GRN were related to lysosome and va ### Exercise 1 - STEP 11 (save an image) -start +start **Notes** about biological interpretation of the results: @@ -371,13 +371,9 @@ Drug-interactions and miRNA-target-predictions nodes are displayed in gray. The start -### Exercise 3 - STEP 4 +### Exercise 3 - STEP 4/ STEP5 -start - -### Exercise 3 - STEP 5 - -start +start ### Exercise 3 - STEPS 6 @@ -392,7 +388,9 @@ Drug-interactions and miRNA-target-predictions nodes are displayed in gray. The ### Exercise 3 - STEP 8 -start +start + + start diff --git a/Module6/genemania/images/GM31_v2.png b/Module6/genemania/images/GM31_v2.png new file mode 100644 index 0000000..91ec25d Binary files /dev/null and b/Module6/genemania/images/GM31_v2.png differ diff --git a/Module6/genemania/images/GM35_2.png b/Module6/genemania/images/GM35_2.png new file mode 100644 index 0000000..ba4629a Binary files /dev/null and b/Module6/genemania/images/GM35_2.png differ diff --git a/docs/Module6/genemania/images/GM31_v2.png b/docs/Module6/genemania/images/GM31_v2.png new file mode 100644 index 0000000..91ec25d Binary files /dev/null and b/docs/Module6/genemania/images/GM31_v2.png differ diff --git a/docs/Module6/genemania/images/GM35_2.png b/docs/Module6/genemania/images/GM35_2.png new file mode 100644 index 0000000..ba4629a Binary files /dev/null and b/docs/Module6/genemania/images/GM35_2.png differ diff --git a/docs/genemania_web.html b/docs/genemania_web.html index 19d45cb..e73d548 100644 --- a/docs/genemania_web.html +++ b/docs/genemania_web.html @@ -762,7 +762,7 @@

Force directed layout

Exercise 1 - STEP 11 (save an image)

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Notes about biological interpretation of the results:

A paper describing the interaction between GRN and SORT1 and demonstrates how finding related genes could be relevant for elaborating therapy:

Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency. Lee et al. Hum Mol Genet. 2014 March 15; 23(6): 1467–1478. PMCID:PMC3929086
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Exercise 3 - STEP 4

Exercise 3 - STEP 5

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Exercise 3 - STEPS 6

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Exercise 3 - STEP 7

Exercise 3 - STEP 8

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